Create issue ticket

43 Possible Causes for Almond-Shaped Eyes, Downturned Corners of the Mouth

  • X-Linked Intellectual Disability Type Nascimento

    corners of mouth Enophthalmos Low posterior hairline Macrocephaly Prominent supraorbital ridges Synophrys Thin vermilion border Upslanted palpebral fissure ... ...[familydiagnosis.com] […] type Nascimento (MIM #300860), caused by mutations in UBE2A (MIM *312180), is characterized by craniofacial dysmorphism (synophrys, prominent supraorbital ridges, deep-set, almond-shaped[ncbi.nlm.nih.gov] corners of mouth ; Dry skin ; Echolalia ; Hirsutism ; Hypointensity of cerebral white matter on MRI ; Increased body weight ; Intellectual disability ; Low posterior hairline[mousephenotype.org]

  • Prader-Willi Syndrome

    These include a narrow face, almond-shaped eyes, small-appearing mouth, a thin upper lip with downturned corners of the mouth, and full cheeks.[rarediseases.about.com] The clinical appearance of PWS includes dysmorphic facial features with almond-shaped eyes, a narrow bifrontal diameter, and a thin upper lip; short stature; central obesity[ncbi.nlm.nih.gov] Fig 1: Dysmorphic facial features: high prominent forehead, narrow bifrontal diameter, downturned corners of the mouth, micrognathia.[atlasgeneticsoncology.org]

  • Native American Myopathy

    corners of the mouth, short stature, and marked susceptibility to malignant hyperthermia.[ncbi.nlm.nih.gov] , bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary[eyewiki.aao.org] corners of mouth Downturned corners of the mouth Downturned mouth [ more ] 0002714 Feeding difficulties Feeding problems Poor feeding [ more ] 0011968 Flexion contracture[rarediseases.info.nih.gov]

  • Disorder of Sex Development - Intellectual Disability Syndrome

    Showing of 31 80%-99% of people have these symptoms Deeply set eye Deep set eye Deep-set eyes Sunken eye [ more ] 0000490 Downturned corners of mouth Downturned corners of[rarediseases.info.nih.gov] Children may be born with almond-shaped eyes, a narrowing of the head at the temples, a turned-down mouth and a thin upper lip. Poor sucking reflex.[mayoclinic.org] corners of mouth 59 32 hallmark (90%) Very frequent (99-80%) HP:0002714 12 kyphosis 59 32 hallmark (90%) Very frequent (99-80%) HP:0002808 13 genu valgum 59 32 hallmark ([malacards.org]

  • Brooks Wisniewski Brown Syndrome

    Full cheeks Hypsarrhythmia Brisk reflexes Conductive hearing impairment Brachydactyly Gastroesophageal reflux Recurrent respiratory infections Downturned corners of mouth[mendelian.co] Deeply set eyes and almond shaped palpebral fissures were noted. The inner canthal distance was 2.4 cm (- 1 SD), the outer canthal distance 7.1 cm (-4 SD).[documents.tips] […] fingernails Microcornea Narrow face Postnatal growth retardation Thick vermilion border Sparse hair Nephritis Smooth philtrum Thick eyebrow Eczema Prominent nose Phimosis Wide mouth[mendelian.co]

  • Frontonasal Dysplasia

    […] of the mouth.[ncbi.nlm.nih.gov] Ocular: narrowed eye slits, almond shaped eyes, epicanthal folds (extra eyelid tissue), epibulbar dermoids (benign tumors of the eye), upper eyelid colombas (full thickness[en.wikipedia.org] Facial features were remarkable by nasal deformity with creased ridge and depressed or absent tip, widely spaced eyes, almond-shaped palpebral fissures, and downturned corners[ncbi.nlm.nih.gov]

  • Blepharoptosis - Myopia - Ectopia Lentis Syndrome

    corners of mouth Synophrys Hyperlordosis Infantile muscular hypotonia Upslanted palpebral fissure Kyphosis Long philtrum Abnormality of the skeletal system Right ventricular[mendelian.co] , bushy eyebrows/XLD/SLC9A6/#300243 CK SYNDROME/Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes/XLR/NSDHL/#300831 COCKAYNE SYNDROME/Pigmentary[eyewiki.org] , bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary[eyewiki.aao.org]

  • SHORT Syndrome

    corners of the mouth, micrognathia and prominent (but not typically low-set or posteriorly located) ears.[orpha.net] Congenital neurobehavioral disorder characterized by rounded face, low forehead, almond shaped eyes, squinting, hypogonadism, hypotonia, insatiable appetite leading to obesity[icd10data.com] The corners of the mouth tend to be downturned.[hgfound.org]

  • X-linked Intellectual Disability Type Abidi

    corners of the mouth), and a large head circumference or macrocephaly, 3.) skin abnormalities (generalized hirsutism, dry skin, hair whorls, onychodystrophy especially of[link.springer.com] […] type Nascimento (MIM #300860), caused by mutations in UBE2A (MIM *312180), is characterized by craniofacial dysmorphism (synophrys, prominent supraorbital ridges, deep-set, almond-shaped[ojrd.biomedcentral.com] Facial phenotype is characterized by a broad face, flat midface, synophrys and/or prominent eyebrows, almond shaped eyes, low nasal bridge, prominent columella of the nose[link.springer.com]

  • Hypertelorism and Tetralogy of Fallot

    Dysmorphic features included wide face with brachycephaly, plagiocephaly, hypertelorism, long eyelashes, thin vermilion border, downturned corners of the mouth, low-set ears[genome.jp] Prader-Willi15 (paternal) imprinting or deletionProminent nasal bridge; almond-shaped eyes; thin upper lip; short stature; obesity; small hands and feet;Hyperphagia; hypotonia[dontforgetthebubbles.com] […] with downturned corners, short neck with low posterior hairline, brachycephaly, maxillary hypoplasia, and multiple skeletal anomalies.[en.wikibooks.org]

Further symptoms

Similar symptoms