Create issue ticket

144 Possible Causes for Almond-Shaped Eyes, Muscle Hypotonia, Strabismus

  • Prader-Willi Syndrome

    The clinical appearance of PWS includes dysmorphic facial features with almond-shaped eyes, a narrow bifrontal diameter, and a thin upper lip; short stature; central obesity[ncbi.nlm.nih.gov] Because of weak muscles (hypotonia), the infant is not able to drink from a bottle and may need special feeding techniques or tube feedings until his/her muscles become stronger[rarediseases.about.com] Strabismus was present in 25 (54%) patients: 22 (48%) patients had esotropia and three (7%) had exotropia. Nine patients either received or required strabismus surgery.[ncbi.nlm.nih.gov]

  • Down Syndrome

    Some common physical features of Down syndrome include: A flattened face, especially the bridge of the nose Almond-shaped eyes that slant up A short neck Small ears A tongue[cdc.gov] From Wikidata Jump to navigation Jump to search chromosomal disease characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused[wikidata.org] Periocular infection is a rare complication of strabismus surgery.[ncbi.nlm.nih.gov]

  • Velocardiofacial Syndrome

    […] includes: cleft palate, usually of the soft palate (the roof of the mouth nearest the throat which is behind the bony palate); heart problems; similar faces (elongated face, almond-shaped[healthieryou.com] Distinct physical features sometimes associated with the syndrome include loss of muscle tone (hypotonia), small slender stature, tapered hands and fingers, small head circumference[rarediseases.org] Strabismus occurs in 10-15 percent of patients. Astigmatism, myopia, and hyperopia occur with the same frequency as in the general population.[clinicaladvisor.com]

  • CK Syndrome

    , bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary[eyewiki.aao.org] Muscular dystrophy causes affected infants to have severe hypotonia (low muscle tone), which might be noted as “floppy baby” syndrome.[rarediseases.org] […] disability, seizures, spasticity, atrophy of optic discs, microcephaly, plagiocephaly, skeletal abnormalities, and minor facial anomalies, including a high nasal bridge, strabismus[ncbi.nlm.nih.gov]

  • Dubowitz Syndrome

    Congenital neurobehavioral disorder characterized by rounded face, low forehead, almond shaped eyes, squinting, hypogonadism, hypotonia, insatiable appetite leading to obesity[icd10data.com] Low or weak muscle tone 0001252 Neuroblastoma Cancer of early nerve cells 0003006 Otitis media Middle ear infection 0000388 Pes planus Flat feet Flat foot [ more ] 0001763[rarediseases.info.nih.gov] Ocular problems occur in about 20%: strabismus, blefarophimosis, ptosis, telecanthus and epicanthal folds being the most frequent ones.[ncbi.nlm.nih.gov]

  • Autosomal Dominant Mental Retardation Type 21

    Deletion of chromosome 22; usually de novo but may be inherited in an autosomal dominant manner Cleft palate; congenital heart defect; speech delay; elongated face with almond-shaped[aafp.org] A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia.[mitomap.org] […] rare type of strabismus.[tsbvi.edu]

  • Craniofrontonasal Dysplasia

    Ocular: narrowed eye slits, almond shaped eyes, epicanthal folds (extra eyelid tissue), epibulbar dermoids (benign tumors of the eye), upper eyelid colombas (full thickness[en.wikipedia.org] Some individuals affected by CFND may also have diminished muscle tone (hypotonia), developmental delays, hearing impairment (sensorineural deafness), a sunken chest (pectus[rarediseases.org] All three patients who underwent strabismus surgery showed improvement in ocular alignment postoperatively.[ncbi.nlm.nih.gov]

  • Williams-Beuren Syndrome

    They also have unique pixie-like facial features–almond shaped eyes, oval ears, full lips, small chins, narrow faces, and broad mouths.[autism.com] People with this condition may also have weak muscle tone (hypotonia) and abnormal movements, such as involuntary movements of one side of the body that mirror intentional[ghr.nlm.nih.gov] We undertook this study to evaluate the characteristics of the strabismus in Williams syndrome.[ncbi.nlm.nih.gov]

  • Weaver Syndrome

    I have typical characteristics of Weaver Syndrome; large birth size, accelerated growth, atypical face view (big ears, big tongue, small chin, almond-shaped eyes), tall in[rumeysagelgi.com] Other common symptoms include hypertonia (increased muscle tone, tight muscles) as well as hypotonia (decreased muscle tone, "floppy" muscles) and a hoarse low-pitched cry[encyclopedia.com] […] hypertelorism (96%) large, low-set ears (96%) increased bifrontal diameter (95%) telecanthus (95%) others: long and accentuated philtrum, macrocephaly, dysplastic ears, strabismus[sites.google.com]

  • Wolf-Hirschhorn Syndrome

    15p12 Mental retardation Early failure to thrive followed by compulsive eating disorder and obesity at about 2 yr Decreased muscle mass Small hands and feet Hypogonadism Almond-shaped[alpfmedical.info] Generalized muscle hypotonia was observed at birth.[ncbi.nlm.nih.gov] In all cases exhibiting strabismus, an exodeviation was present.[ncbi.nlm.nih.gov]

Similar symptoms