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35 Possible Causes for Alopecia, Focal Hyperkeratosis on Palms and Soles, Focal Keratoderma of Soles

  • Diffuse Palmoplantar Keratoderma

    […] involving the whole of the palms and soles. [1] : 506-8 [2] : 213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses[like2do.com] The hair is sparse and pale, and the alopecia can be patchy or total. Hair loss may lead to total alopecia by puberty.[ncbi.nlm.nih.gov] Clinically, there is hyperkeratosis on the palms and soles.[indianpediatrics.net]

  • Epidermolysis Bullosa Simplex Type Cockayne-Touraine

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Nail dystrophy, milia atrophic scarring and scarring alopecia are seen.[kissesforkatie.org] Cicatricial JEB• Bistering heal with scarring and result in loss of nails, alopecia, syndactyly and contractures.• Involvement of oral mucosa with stenosis of anterior nares[slideshare.net]

  • Pachyonychia Congenita Type 1

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] Authors, Source MeSH Adult Alopecia Blister Bone Diseases Cataract Child, Preschool Cornea Darier Disease Eye Diseases Female Humans Intellectual Disability Keratosis Leukoplakia[unboundmedicine.com] Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles (palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org]

  • Epidermolysis Bullosa

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Other characteristic features of this condition include alopecia, malformed fingernails and toenails, and irregular tooth enamel.[ghr.nlm.nih.gov] Extracutaneous 4 manifestations include: dystrophy or absence of nails, sparse head hair or alopecia, excessive dental caries, microstomia, mouth ulcers, lingual tip fixation[revistanefrologia.com]

  • Palmoplantar Keratosis

    […] x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms.[en.wikipedia.org] […] of palms and soles, sometimes accompanied by other cutaneous or systemic features.[doi.org] alopecia.[diseaseinfosearch.org]

  • Erythema Palmaris Hereditarium

    […] involving the whole of the palms and soles. [1] :506–8 [2] :213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses of[ipfs.io] […] of palms and soles with honeycombing was absent [Figure 1], [Figure 2], [Figure 3], and [Figure 5].[jdrntruhs.org] Alopecia antibody deficiency Alopecia totalis Alopecia universalis Alopecia-contractures-dwarfism-intellectual disability syndrome Alopecia-epilepsy-pyorrhea-intellectual[se-atlas.de]

  • Lamellar Ichthyosis

    […] and soles ( Lucker et al., 1994 ).For a discussion of phenotypic and genetic heterogeneity of palmoplantar keratoderma, see epidermolytic PPK ( OMIM ).[mendelian.co] Generalized large, dark, platelike scale increased in flexures; erythroderma; ectropion; palmoplantar keratoderma; decreased sweating with heat intolerance Hair: Scarring alopecia[cram.com] […] of the palms and soles - Can be diffuse, focal or punctate - Caused by defects in keratins, which make up the cytoskeleton in epithelial cells Vorner-Unna-Thost type - Diffuse[flashcardbook.com]

  • Pachyonychia Congenita

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] Differential diagnoses include alopecia areata, androgenetic alopecia and traction alopecia/ trichotillomania.[ncbi.nlm.nih.gov] Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles ( palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org]

  • Howell-Evans Syndrome

    Focal keratodermas are palmoplantar keratodermas (PPK) that involve only some areas of the palms or soles, usually over pressure points.[dermnetnz.org] 20 nail dystrophy (found in alopecia areata, LP, PSO, eczema) What diseases are trachyonychia found in?[brainscape.com] […] on the palms and soles (Lucker et al., 1994).[ncbi.nlm.nih.gov]

  • Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] It remains to be elucidated whether diffuse alopecia results from PLEC mutations and/or from environmental factors.[ncbi.nlm.nih.gov] We report a case of EBS-MD with diffuse alopecia.[ncbi.nlm.nih.gov]

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