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20 Possible Causes for Alopecia, Focal Keratoderma of Soles, Hypoplastic Nails

  • Epidermolysis Bullosa

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Hypoplastic enamel formation causes tooth decay. Nail dystrophy and alopecia are also common. They have a normal life expectancy and ability to reproduce.[patient.info] Other characteristic features of this condition include alopecia, malformed fingernails and toenails, and irregular tooth enamel.[ghr.nlm.nih.gov]

  • Diffuse Palmoplantar Keratoderma

    […] involving the whole of the palms and soles. [1] : 506-8 [2] : 213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses[like2do.com] […] dystrophy), Huriez syndrome (scleroatrophic changes on the dorsal aspect of the hands and hypoplastic nails in addition to the PPK).[indianpediatrics.net] The hair is sparse and pale, and the alopecia can be patchy or total. Hair loss may lead to total alopecia by puberty.[ncbi.nlm.nih.gov]

  • Palmoplantar Keratosis

    […] x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms.[en.wikipedia.org] nail changes.[intechopen.com] alopecia.[diseaseinfosearch.org]

  • Lamellar Ichthyosis

    […] and soles ( Lucker et al., 1994 ).For a discussion of phenotypic and genetic heterogeneity of palmoplantar keratoderma, see epidermolytic PPK ( OMIM ).[mendelian.co] […] in Nail Patella syndrome P-posterior iliac horns A-Absent patella T-thickened scapula E- eye-Lester iris L-lunulae, triangular L - gLomerulonephritis Granular cell tumor[brainscape.com] Generalized large, dark, platelike scale increased in flexures; erythroderma; ectropion; palmoplantar keratoderma; decreased sweating with heat intolerance Hair: Scarring alopecia[cram.com]

  • Epidermolysis Bullosa Simplex Type Cockayne-Touraine

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Hypoplastic enamel formation causes tooth decay. Nail dystrophy and alopecia are also common. They have a normal life expectancy and ability to reproduce.[patient.info] Nail dystrophy, milia atrophic scarring and scarring alopecia are seen.[kissesforkatie.org]

  • Howell-Evans Syndrome

    Focal keratodermas are palmoplantar keratodermas (PPK) that involve only some areas of the palms or soles, usually over pressure points.[dermnetnz.org] […] dystrophy), Huriez syndrome (scleroatrophic changes on the dorsal aspect of the hands and hypoplastic nails in addition to the PPK).[indianpediatrics.net] 20 nail dystrophy (found in alopecia areata, LP, PSO, eczema) What diseases are trachyonychia found in?[brainscape.com]

  • Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Hypoplastic enamel formation causes tooth decay. Nail dystrophy and alopecia are also common. They have a normal life expectancy and ability to reproduce.[patient.info] It remains to be elucidated whether diffuse alopecia results from PLEC mutations and/or from environmental factors.[ncbi.nlm.nih.gov]

  • Atrophodermia Vermiculata

    Focal palmoplantar keratoderma is a skin condition characterized by the development of painful blisters and calluses on the soles of the feet and, less commonly, on the palms[findzebra.com] Skin lesion Cicatricial alopecia Ulerythema List of cutaneous conditions[en.wikipedia.org] See also Skin lesion Cicatricial alopecia Ulerythema List of cutaneous conditions[wikidoc.org]

  • Tricho-Oculo-Dermo-Vertebral Syndrome

    focal keratoderma over the soles.[plasticsurgerykey.com] Additional features reported in the isolated case include a narrow palate, hypoplastic nails, eyebrow anomalies, a unilateral simian crease, and poorly formed dermatoglyphics[findzebra.com] (PPK; alopecia congenita with keratosis palmoplantaris, OMIM 104100).[researchgate.net]

  • Cooks Syndrome

    […] on the margins of the palms and soles and focal hyperkeratosis on the dorsum of the hands and feet.[ncbi.nlm.nih.gov] Chapter First Online: 06 December 2014 Abstract Cooks syndrome is a brachydactyly with absent or hypoplastic nails affecting all digits.[link.springer.com] There is a condition called alopecia areata that affects an estimated 4.5 million people in the United States.[metrowestdailynews.com]

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