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21 Possible Causes for Alopecia, Focal Keratoderma of Soles, Jaundice

  • Growth Hormone Deficiency

    Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it can be acquired[ncbi.nlm.nih.gov] The proband is a 5-year-old girl who presented with neonatal hypoglycaemia and prolonged jaundice.[ncbi.nlm.nih.gov] The non-inflammatory type usually will not be complicated by scarring alopecia.[ncbi.nlm.nih.gov]

  • Pachyonychia Congenita Type 1

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] […] stature Global developmental delay Hydrocephalus Renal insufficiency Hypoglycemia Macrotia Hydronephrosis Feeding difficulties in infancy Intellectual disability, moderate Jaundice[mendelian.co] Authors, Source MeSH Adult Alopecia Blister Bone Diseases Cataract Child, Preschool Cornea Darier Disease Eye Diseases Female Humans Intellectual Disability Keratosis Leukoplakia[unboundmedicine.com]

  • Erythema Palmaris Hereditarium

    […] involving the whole of the palms and soles. [1] :506–8 [2] :213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses of[ipfs.io] Chronic Liver Disease can give rise to numerous extrahepatic disorders among which skin disease occupy a central place Jaundice, xerosis, pruritis, pigmentary changes, loss[medical-dictionary.thefreedictionary.com] Alopecia antibody deficiency Alopecia totalis Alopecia universalis Alopecia-contractures-dwarfism-intellectual disability syndrome Alopecia-epilepsy-pyorrhea-intellectual[se-atlas.de]

  • Lamellar Ichthyosis

    […] and soles ( Lucker et al., 1994 ).For a discussion of phenotypic and genetic heterogeneity of palmoplantar keratoderma, see epidermolytic PPK ( OMIM ).[mendelian.co] Generalized large, dark, platelike scale increased in flexures; erythroderma; ectropion; palmoplantar keratoderma; decreased sweating with heat intolerance Hair: Scarring alopecia[cram.com] Horn-Like Projection Hyperkeratosis Hyperpigmentation Hypertrichosis Hypertrophy and Folding of the Skin of the Scalp Hypopigmented Hypopigmented Patches Intertrigo Itching Jaundice[pongpdf.com]

  • Palmoplantar Keratosis

    […] x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms.[en.wikipedia.org] Less commonly the condition may present due to spread elsewhere such as the lungs (breathlessness, cough), liver (jaundice, abdominal swelling due to fluid, ascites), bones[ojrd.biomedcentral.com] alopecia.[diseaseinfosearch.org]

  • Pachyonychia Congenita

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] Avoid in newborns due to the potential for an increase in free bilirubin, jaundice, and development of kernicterus.[simplygoodnaturalfoods.com] Differential diagnoses include alopecia areata, androgenetic alopecia and traction alopecia/ trichotillomania.[ncbi.nlm.nih.gov]

  • Atrophodermia Vermiculata

    Focal palmoplantar keratoderma is a skin condition characterized by the development of painful blisters and calluses on the soles of the feet and, less commonly, on the palms[findzebra.com] […] neuropathy Tremor Gait disturbance Tics Pain Autosomal dominant inheritance Sensory impairment Failure to thrive Growth delay Short stature Generalized amyotrophy Osteoporosis Jaundice[mendelian.co] Skin lesion Cicatricial alopecia Ulerythema List of cutaneous conditions[en.wikipedia.org]

  • Howell-Evans Syndrome

    Focal keratodermas are palmoplantar keratodermas (PPK) that involve only some areas of the palms or soles, usually over pressure points.[dermnetnz.org] It can be characterized by varying degrees of anemia, jaundice, an enlarged spleen, or combinations of these conditions.[pedsinreview.aappublications.org] 20 nail dystrophy (found in alopecia areata, LP, PSO, eczema) What diseases are trachyonychia found in?[brainscape.com]

  • Upper Urinary Tract Infection

    Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles (palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org] Young children sometimes present with irritability, poor feeding, vomiting, or jaundice.[physio-pedia.com] […] palmoplantar keratoderma; see these terms) and disorders manifesting with dystrophic nails such as epidermolysis bullosa, Clouston syndrome (distinguished by the presence of alopecia[orpha.net]

  • Pancytopenia

    Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles ( palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org] .  Weight loss, fever ( Inflammatory or malignancy)  Jaundice ( Hepatitis B or C)  Joint pain (SLE)  History of blood loss 7.[slideshare.net] […] palmoplantar keratoderma; see these terms) and disorders manifesting with dystrophic nails such as epidermolysis bullosa, Clouston syndrome (distinguished by the presence of alopecia[orpha.net]

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