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29 Possible Causes for Alopecia, Focal Keratoderma of Soles, Osteoporosis

  • Growth Hormone Deficiency

    Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it can be acquired[ncbi.nlm.nih.gov] The role of anti-RANK ligand (RANKL) antibody for osteoporosis on hepatitis in patients with aGHD is still unknown.[ncbi.nlm.nih.gov] The non-inflammatory type usually will not be complicated by scarring alopecia.[ncbi.nlm.nih.gov]

  • Epidermolysis Bullosa

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] For some types of EB, the internal mucosa is also affected: nutrition can be compromised, resulting in osteoporosis, and general failure to thrive: quite young children can[debra-international.org] Other characteristic features of this condition include alopecia, malformed fingernails and toenails, and irregular tooth enamel.[ghr.nlm.nih.gov]

  • Diffuse Palmoplantar Keratoderma

    […] involving the whole of the palms and soles. [1] : 506-8 [2] : 213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses[like2do.com] Neurocutaneous melanosis sequence Neuroectodermal melanolysosomal disease Nevoid lentiginosis Nevus elasticus Oculo-cerebro-cutaneous syndrome Oculodermal melanocytosis Osteoporosis[icdlist.com] The hair is sparse and pale, and the alopecia can be patchy or total. Hair loss may lead to total alopecia by puberty.[ncbi.nlm.nih.gov]

  • Erythema Palmaris Hereditarium

    […] involving the whole of the palms and soles. [1] :506–8 [2] :213 Focal Focal palmoplantar keratoderma, a type of palmoplantar keratoderma in which large, compact masses of[ipfs.io] (see also Osteoporosis) 733.0 [737.41] poliomyelitis (see also Poliomyelitis) 138 [737.41] radiation 737.11 tuberculosis (see also Tuberculosis) 015.0 [737.41] Kümmell's[theodora.com] Alopecia antibody deficiency Alopecia totalis Alopecia universalis Alopecia-contractures-dwarfism-intellectual disability syndrome Alopecia-epilepsy-pyorrhea-intellectual[se-atlas.de]

  • Lamellar Ichthyosis

    […] and soles ( Lucker et al., 1994 ).For a discussion of phenotypic and genetic heterogeneity of palmoplantar keratoderma, see epidermolytic PPK ( OMIM ).[mendelian.co] The evidence of severe osteoporosis with hyperparathyroidism secondary to malabsorption suggested the occurrence of celiac disease.[ncbi.nlm.nih.gov] Generalized large, dark, platelike scale increased in flexures; erythroderma; ectropion; palmoplantar keratoderma; decreased sweating with heat intolerance Hair: Scarring alopecia[cram.com]

  • Palmoplantar Keratosis

    […] x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms.[en.wikipedia.org] Some authors also reported other findings, such as microphtalmus, intracranial calcification, arachnodactyly, osteoporosis, abnormal hepatic function, renal abnormalities[clinicadavilla.com.br] alopecia.[diseaseinfosearch.org]

  • Pachyonychia Congenita

    Fig 2: Showing focal keratoderma on soles. Fig 3: Showing pachyonychia in hands and feet. Fig 4: Showing leukoplakia on tongue and angular cheilitis of mouth.[edoj.org.eg] Vigorous use of water jets should be avoided with fractures, known blood clots, bleeding disorders, severe osteoporosis, open wounds, or during pregnancy.[simplygoodnaturalfoods.com] Differential diagnoses include alopecia areata, androgenetic alopecia and traction alopecia/ trichotillomania.[ncbi.nlm.nih.gov]

  • Epidermolysis Bullosa Simplex Type Cockayne-Touraine

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] […] contracture Keratitis Cataract Hearing impairment Paronychia Laryngeal stridor Laryngeal stenosis Stenosis of the external auditory canal Hoarse voice Dehydration Dyspnea Osteoporosis[mendelian.co] Nail dystrophy, milia atrophic scarring and scarring alopecia are seen.[kissesforkatie.org]

  • Palmoplantar Keratoderma-Spastic Paralysis Syndrome

    […] and nail dystrophy" [ 1 ] ) is an autosomal dominant or x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser[en.academic.ru] Radiographs of the hands and feet revealed bone rarefactions and osteoporosis distal to the constrictive rings and an absence of the distal phalanges of the fifth toes.[rbcp.org.br] Alopecia congenita keratosis palmoplantaris 0 *Alopecia/congenital *Keratoderma, Palmoplantar.[reference.md]

  • Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] These supplements may help prevent osteoporosis (thinning bones).[medlineplus.gov] It remains to be elucidated whether diffuse alopecia results from PLEC mutations and/or from environmental factors.[ncbi.nlm.nih.gov]

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