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15 Possible Causes for Alopecia, Focal Keratoderma of Soles, Poor Growth

  • Growth Hormone Deficiency

    Palmoplantar keratoderma (PPK) is a diverse group of disorders, characterized by thickening of the palms and soles, which are subdivided into focal or diffuse; it can be acquired[ncbi.nlm.nih.gov] Patients with NFNS who show poor growth should be evaluated for GHD.[ncbi.nlm.nih.gov] The non-inflammatory type usually will not be complicated by scarring alopecia.[ncbi.nlm.nih.gov]

  • Epidermolysis Bullosa

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Blisters in these areas can make it difficult to eat and lead to nutritional problems or poor growth.[rch.org.au] Other characteristic features of this condition include alopecia, malformed fingernails and toenails, and irregular tooth enamel.[ghr.nlm.nih.gov]

  • Lamellar Ichthyosis

    […] and soles ( Lucker et al., 1994 ).For a discussion of phenotypic and genetic heterogeneity of palmoplantar keratoderma, see epidermolytic PPK ( OMIM ).[mendelian.co] […] soles are also involved - May have nail dystrophy, poor growth, alopecia Congenital ichthyosis treatment - Topical emollients with glycolic acid, lactic acid, urea and glycerin[flashcardbook.com] Generalized large, dark, platelike scale increased in flexures; erythroderma; ectropion; palmoplantar keratoderma; decreased sweating with heat intolerance Hair: Scarring alopecia[cram.com]

  • Epidermolysis Bullosa Simplex Type Cockayne-Touraine

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] In many cases chronic malnutrition, growth retardation and anemia may ensue.[blog.ebinfoworld.com] Nail dystrophy, milia atrophic scarring and scarring alopecia are seen.[kissesforkatie.org]

  • Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] Blisters in these areas can make it difficult to eat and lead to nutritional problems or poor growth.[rch.org.au] It remains to be elucidated whether diffuse alopecia results from PLEC mutations and/or from environmental factors.[ncbi.nlm.nih.gov]

  • Atrophodermia Vermiculata

    Focal palmoplantar keratoderma is a skin condition characterized by the development of painful blisters and calluses on the soles of the feet and, less commonly, on the palms[findzebra.com] Skin lesion Cicatricial alopecia Ulerythema List of cutaneous conditions[en.wikipedia.org] See also Skin lesion Cicatricial alopecia Ulerythema List of cutaneous conditions[wikidoc.org]

  • Upper Urinary Tract Infection

    Pachyonychia congenita Clinical features of pachyonychia congenita Palms and soles Thickened or calloused palms and soles (palmoplantar hyperkeratosis or keratoderma, particularly[dermnetnz.org] In infants and young children, symptoms may be non-specific, such as irritability, vomiting, diarrhoea, refusing food and poor growth.[guiasalud.es] […] palmoplantar keratoderma; see these terms) and disorders manifesting with dystrophic nails such as epidermolysis bullosa, Clouston syndrome (distinguished by the presence of alopecia[orpha.net]

  • Epidermolysis Bullosa Simplex Type Kobner

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] If poor weight gain and reduced growth have occurred because symptoms of EB make eating impossible, surgery can be used to implant a feeding tube into the body through an[your.md] […] areata 140 141 Tinea capitis and kerion 141 142 Traction alopecia and hair pulling 142 143 Ectodermal dysplasias 142 145 Telogen and anagen effluvium 144 146 Pachyonychia[books.google.de]

  • Autosomal Recessive Epidermolysis Bullosa Simplex

    ., belt line) Generalized Generalized Generalized Grouped (herpetiform) No No Sometimes Yes Mucosal Rare Occasionally Occasionally Often Hyperkeratosis of palms & soles (keratoderma[ncbi.nlm.nih.gov] If poor weight gain and reduced growth have occurred because symptoms of EB make eating impossible, surgery can be used to implant a feeding tube into the body through an[your.md] The patient subsequently developed cutaneous atrophy, nail dystrophy, milia and alopecia.[ncbi.nlm.nih.gov]

  • Tricho-Oculo-Dermo-Vertebral Syndrome

    focal keratoderma over the soles.[plasticsurgerykey.com] CD-associated breast malignancy often exhibits poor prognostic features, including higher grade, larger size, aggressive growth patterns, lymph node involvement, and hormone-receptor[pocketdentistry.com] (PPK; alopecia congenita with keratosis palmoplantaris, OMIM 104100).[researchgate.net]

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