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4,038 Possible Causes for Alopecia, High Pitched Voice, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] dysostosis syndrome Skin fragility-woolly hair-palmoplantar keratoderma syndrome Osteopathia striata cranial sclerosis Brachycephalofrontonasal dysplasia Thumb deformity, alopecia[checkrare.com] Speech delays, an unusually soft, high-pitched voice, submucous cleft palate, and velopharyngeal insufficiency were noted in childhood.[ncbi.nlm.nih.gov]

  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Affected individuals displayed telangiectases, alopecia, and other malignancies such as nonmelanoma skin cancer, and less commonly breast cancer and cervical cancer.[preventiongenetics.com] She also displayed high-pitched voice. The age of menarche was 15 years. She had regular menstrual cycles.[termedia.pl]

  • Laron Syndrome

    Young adults have various degrees of alopecia, more pronounced in males.[ncbi.nlm.nih.gov] Clinically, all three presented with the typical craniofacies of Laron syndrome, consisting of prominent forehead and hypoplastic nasal bridge, high-pitched voice, short stature[ncbi.nlm.nih.gov] Ateliotic dwarfism without insulinopenia Congenital malformation syndromes associated with short stature Constitutional short stature Dolichocephalic dwarfism Dwarfism Dwarfism, alopecia[icd9data.com]

    Missing: Wide Space Between the First and Second Toe
  • Congenital Muscular Dystrophy

    Abstract Congenital muscular dystrophies are a group of common genetically determined disorders often transmitted with a recessive mode of inheritance. In recent years, several deficiencies of proteins from the muscle membrane, extra cellular matrix, sarcomere, muscle cytosol and the nucleus have been described to[…][ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Werner Syndrome

    Werner syndrome (WS), such as high-pitched voice, scleroderma, lipoatrophy and atherosclerosis, several cardinal features of WS, including short stature, premature graying/alopecia[ncbi.nlm.nih.gov] The patient had a high-pitched voice, hoarseness, a characteristic bird-like facial appearance with a beak-shaped nose, canities and juvenile cataracts.[ncbi.nlm.nih.gov] Clinical findings include: senile appearance, short stature, grey hair, alopecia, bird-like face, scleroderma-like skin changes, skin ulcers, voice abnormalities, cataracts[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Progeria

    At 18 months of age, irregular pigmentary changes of the abdomen, early occipital alopecia, superficial scalp veins, glyphic nasal tip, absent ear lobules, coarse hair that[ncbi.nlm.nih.gov] voice.[ncbi.nlm.nih.gov] The children usually present in late infancy and early childhood with a characteristic phenotype of alopecia; short stature; abnormal skin, teeth, and nails; beaked nose;[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Seckel Syndrome Type 2

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] retardation syndrome type 3 PGAP2 Hyperphosphatasia with mental retardation syndrome type 4 PGAP3 Hyperphosphatasia with mental retardation syndrome type 5 PIGW Hypogonadism, alopecia[centogene.com] Affected individuals displayed telangiectases, alopecia, and other malignancies such as nonmelanoma skin cancer, and less commonly breast cancer and cervical cancer.[preventiongenetics.com]

  • Wiedemann-Rautenstrauch Syndrome

    Prominent scalp veins are noticeable (made more obvious by alopecia), as well as prominent eyes.[teamcarlyq.com] Infants may have dysphonic, horse cry and older children may have an unusual high-pitched voice.[rarediseases.org] […] physical traits including: A bigger head Large eyes A small lower jaw A thin nose with a "beaked" tip Ears that stick out Veins you can see Slow and abnormal tooth growth A high-pitched[webmd.com]

    Missing: Wide Space Between the First and Second Toe
  • Zinc Deficiency

    Follow-up in 4 months showed no evidence of alopecia, with normal-looking hair.[ncbi.nlm.nih.gov] voice, metallic tinkle, signal, or twitter, then it was a high frequency .[tinnitusformula.com] The characteristic triad of acral and periorificial dermatitis, diarrhea and alopecia was observed in only 6 patients (40%).[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Klinefelter Syndrome

    Sterility (inability to produce live sperm) Overweight Level of activity and endurance lower than others their age Restless sleep patterns, but hard to awake in the morning High-pitched[xxyaware.blogspot.com] […] include: [1] [2] [3] Small, firm testicles Delayed or incomplete puberty with lack of secondary sexual characteristics resulting in sparse facial, body, or sexual hair a high-pitched[rarediseases.info.nih.gov] In severe cases, t hey have relatively high-pitched voices, asexual to feminine body contours as well as breast enlargement, and comparatively little facial and body hair.[anthro.palomar.edu]

    Missing: Wide Space Between the First and Second Toe

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