Create issue ticket

29 Possible Causes for Alpha Interferon Activity Increased, Arthralgia

  • Chronic Fatigue Syndrome

    Individuals with fibromyalgia (FM) and/or chronic fatigue syndrome (CFS) report arthralgias and myalgias.[ncbi.nlm.nih.gov] , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] […] syndrome (CFS) is a condition characterized by impairment of neurocognitive functions and quality of sleep and of somatic symptoms such as recurrent sore throat, muscle aches, arthralgias[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] MUSCULOSKELETAL SYSTEM Musculoskeletal involvement is present in 95% of patients with SLE and manifests as arthralgias, myalgias, or nonerosive inflammatory arthritis. 10[aafp.org] Antimalarials, e.g., hydroxychloroquine, can use to treat arthralgia and skin disease.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    Here we report a case in which an elderly female presented with malar rash, intermittent fever, and arthralgia.[ncbi.nlm.nih.gov] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] Women, on the other hand, suffered from more alopecia, photosensitivity, arthralgia and RP.[doi.org]

  • HIV Infection

    Although some patients with acute HIV-1 infection experience fever, lymphadenopathy, pharyngitis, skin rash, myalgia, arthralgia, and other symptoms, 1-6 a recent prospective[aidsinfo.nih.gov] […] are not generally increased, although expression of IL-1, IL-2, IL-6, IL-12, and interferon-gamma may be elevated.(112) With administration of antiretroviral therapies, these[hivinsite.ucsf.edu] Prospective studies of acute HIV infections show that fever, lymphadenopathy, pharyngitis, diffuse erythematous rash, arthralgia/myalgia, diarrhea, and headache are the commonest[library.med.utah.edu]

  • Drug-Induced Lupus Erythematosus

    Both the arthralgia and fever did not relapse, and anti-ds DNA antibody returned to normal during a follow-up period without treatment.[ncbi.nlm.nih.gov] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] The common features were fever, arthralgia, myalgia, serositis, and the presence of anti-histone autoantibodies.[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov] In addition, these patients may have arthralgia, oligomenorrhea, fluctuating jaundice and cushingoid appearance with striae, hirsutism and acne.[hepatitiscentral.com] There may also be non-specific symptoms like fatigue, malaise, nausea, abdominal discomfort, itching, and arthralgia’s particularly in the small joints. B.[clinicaladvisor.com]

  • Viral Pneumonia

    Retrospective observational reports of combination treatment with ribavirin and pegylated interferon alpha have shown inconsistent results.[clinicaladvisor.com] Adjunct corticosteroids are not recommended and may increase mortality. Mycophenolate demonstrates in vitro activity but was not effective in animal models.[clinicaladvisor.com]

  • Tropical Spastic Paraparesis

    Interferon-alpha and vitamin C are other therapies presenting some benefits in clinical practice, probably due to their anti-viral and immunomodulatory activities observed[eurekaselect.com] Furthermore, inhibitors of histone deacetylase, which increase virus expression but result in a substantial decline in the proviral load, have also been proposed.[eurekaselect.com]

  • Infectious Mononucleosis

    Arthralgias and myalgias occur but are less common than in other viral infectious diseases and are rarely severe.[patient.info] Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] Parainfluenza viruses: sudden myalgia/arthralgia with fever in mild case of tonsillitis. Diphtheria.[lecturio.com]

  • Local Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] She also experienced systemic symptoms including fatigue, arthralgia, malaise, and fever.[mdedge.com] Arthritis in SLE occurs predominately in the hand and knee, yet most joints may be affected. [13] For patients with predominant arthralgias or arthritis, techniques used in[emedicine.medscape.com]

Further symptoms

Similar symptoms