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15 Possible Causes for Alpha Interferon Activity Increased, Chronic Fatigue Syndrome

  • Infectious Mononucleosis

    Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] fatigue syndrome (CFS), and the risks of exercise at various points in the disease process.[ncbi.nlm.nih.gov] These include, but are not limited to, infections in the immunocompromised host, AIDS, Lyme disease, osteomyelitis, endocarditis and chronic fatigue syndrome.[hospitals.jefferson.edu]

  • Chronic Fatigue Syndrome

    , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] Research on the pathophysiology and treatment of chronic fatigue syndrome is reviewed. Chronic fatigue syndrome is diagnosed on the basis of symptoms.[ncbi.nlm.nih.gov] Research on the pathophysiology and treatment of chronic fatigue syndrome is reviewed. RESULTS: Chronic fatigue syndrome is diagnosed on the basis of symptoms.[dx.doi.org]

  • Systemic Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[kaleidoscopefightinglupus.org] Reports pointing to important roles of interferon-alpha, transcription factors, and signaling variations also point to a central role for neutrophils. [21] Genetics There[emedicine.com]

  • HIV Infection

    […] are not generally increased, although expression of IL-1, IL-2, IL-6, IL-12, and interferon-gamma may be elevated.(112) With administration of antiretroviral therapies, these[hivinsite.ucsf.edu] […] indices of immune activation tend to fall, indicating that HIV replication induces the state of high-level activation.(113-117) The plausible hypothesis that HIV-induced[hivinsite.ucsf.edu] […] both TNF and IL-6 levels also are directly correlated with plasma HIV RNA levels.(111) Interestingly, in lymphoid tissue, the primary site of HIV replication, levels of TNF-alpha[hivinsite.ucsf.edu]

  • Chronic Active Hepatitis B

    CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov] Long-term complications Liver cirrhosis Hepatocellular carcinoma ( HCC ) Post‑hepatitis syndrome Chronic fatigue, weakness Nausea, loss of appetite Possible upper quadrant[amboss.com] […] of the smaller dose required and the greater increase in life expectancy of children.[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[kaleidoscopefightinglupus.org] Aphthous ulcers, arthralgia, uveitis Recurrent oral ulcers plus two of the following: eye lesions, genital ulcers, skin lesions Chronic fatigue syndrome Persistent and unexplained[aafp.org]

  • Drug-Induced Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] Other conditions with symptoms similar to lupus include fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome .[northshore.org] Furthermore, chronic use of practolol may cause oculomucocutaneous syndrome, a severe syndrome whose signs include conjunctivitis sicca and psoriasiform rashes, otitis and[wikivisually.com]

  • Human Herpesvirus 6

    , such as interleukin-1β (IL-1β), TNF-α, and alpha interferon (IFN-α), is observed in PBMCs, while NK cell activity associated with IL-15 synthesis is elevated in HHV-6A infection[cmr.asm.org] fatigue syndrome, Lancet, 1991 , vol. 337 (pg. 1346 - 7 ) 22 Viral serologies in patients with chronic fatigue and chronic fatigue syndrome, J Med Virol, 1996 , vol. 50 ([doi.org] Chronic fatigue syndrome (CFS) is an illness currently defined entirely by a combination of non-specific symptoms.[ncbi.nlm.nih.gov]

  • Local Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[mollysfund.org] Reports pointing to important roles of interferon-alpha, transcription factors, and signaling variations also point to a central role for neutrophils. [21] Genetics There[emedicine.medscape.com]

  • Mycobacterium Avium Complex

    Individuals with localized pulmonary MAC infections showed increased activation of monocytes and enhanced monocyte and T-cell tumor necrosis factor alpha (TNF-alpha) production[ncbi.nlm.nih.gov] ("Lady Windermere syndrome", Chest 1992;101:1605 ) AIDS patients have severe infection resembling tuberculosis with impaired T cell immunity; pulmonary involvement is part[pathologyoutlines.com] Genomic DNA from the individual with the brain MAC infection was studied for gamma interferon (IFN-gamma) receptor mutations.[ncbi.nlm.nih.gov]

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