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19 Possible Causes for Alpha Interferon Activity Increased, Endocarditis

  • Systemic Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] Here we describe a case of bacteremia in an infective endocarditis patient with systemic lupus erythematosus (SLE).[ncbi.nlm.nih.gov] Abstract Libman-Sacks endocarditis, one of the most prevalent cardiac presentations of systemic lupus erythematosus, typically affects the aortic or mitral valve; tricuspid[ncbi.nlm.nih.gov]

  • Myocarditis

    The possible modes of action include enhancing natural killer cell activity, inducing production of alpha‐ and gamma‐interferon, improving cardiac microcirculation, and activity[doi.org] (senile) (with calcification) 440.9 myocarditis 429.0 Disease, diseased - see also Syndrome heart (organic) 429.9 with amyloid 277.39 [ 425.7 ] aortic (valve) (see also Endocarditis[icd9data.com] Although cases of histoplasmosis-associated endocarditis and pericarditis have been reported in the literature, cases of histoplasmosis myocarditis are rare.[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] : sterile vegetations on the mitral and aortic valves (rare) pericardial effusion 8 : can be associated with nephritis, Libman-Sacks endocarditis and myocardial dysfunction[radiopaedia.org] […] weight loss multisystem symptoms Examination SKIN: skin and joint involvement common, oral and pharyngeal ulceration, alopcecia CARDIOVASCULAR: pericarditis 15%, myocarditis, endocarditis[lifeinthefastlane.com]

  • Drug-Induced Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] We report a case with typical clinical features of drug-induced lupus erythematosus, together with verrucous endocarditis and pleuropericardial effusion, due to amiodarone[ncbi.nlm.nih.gov] […] due to systemic lupus erythematosus Endocarditis in sle Endocarditis in sle (systemic lupus erythematosus) Glomerular disease due to systemic lupus erythematosus Glomerular[icd9data.com]

  • Infectious Mononucleosis

    Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] These include, but are not limited to, infections in the immunocompromised host, AIDS, Lyme disease, osteomyelitis, endocarditis and chronic fatigue syndrome.[hospitals.jefferson.edu] In EBV infection levels of abnormal circulating Th1 lymphocytes are increased, leading to activation of cell-mediated immunity.[omicsonline.org]

  • Chronic Fatigue Syndrome

    , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] In this latter population, MD appears as a nervous and cardiovascular risk factor more prone to arrhythmias, sudden death, endocarditis, cerebral or visual or inner ear ischaemic[mgwater.com] […] such as disabling lethargy, myalgias, and cognitive impairment, are similar to the effects observed with high dosage treatments of cytokines including interleukin-2 and alpha[aafp.org]

  • HIV Infection

    […] are not generally increased, although expression of IL-1, IL-2, IL-6, IL-12, and interferon-gamma may be elevated.(112) With administration of antiretroviral therapies, these[hivinsite.ucsf.edu] Infective endocarditis occurs almost exclusively in those who use injection drugs.[aafp.org] […] indices of immune activation tend to fall, indicating that HIV replication induces the state of high-level activation.(113-117) The plausible hypothesis that HIV-induced[hivinsite.ucsf.edu]

  • Childhood Dermatomyositis

    Activation of dendritic cells with upregulation of genes induced by type-1 interferon (alpha) in muscle and peripheral blood seems to be central to disease pathogenesis.[ncbi.nlm.nih.gov] M33.90 Dermatopolymyositis, unspecified, organ involvement unspecified 2016 2017 2018 2019 Billable/Specific Code juvenile M33.00 ICD-10-CM Codes Adjacent To M33.00 M32.11 Endocarditis[icd10data.com] Endocarditis; or 6. Sinusitis documented by appropriate medically acceptable imaging. OR B. Stem cell transplantation as described under 114.00E3.[ssa.gov]

  • Local Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] […] or intestines Destruction of red blood cells or anemia of long-term (chronic) disease Fluid around the heart (pericarditis), or inflammation of the heart ( myocarditis or endocarditis[medlineplus.gov] Serious, rare complications are coronary artery vasculitis, valvular involvement, and Libman-Sacks endocarditis.[merckmanuals.com]

  • Singleton Merten Syndrome

    Laboratory evaluation shows increased alpha-interferon ( IFNA1 ) activity with upregulation of interferon signaling and interferon-stimulated gene expression.[mendelian.co] Aims: We report a case of 29 years old male patient who was admitted to our hospital with double mitral and aortic valves endocarditis and staph aureus endocarditis.[thieme-connect.com] Bacterial endocarditis prophylaxis necessary. Caution with use of intravenous induction agents in presence of decreased cardiac output.[accessanesthesiology.mhmedical.com]

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