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15 Possible Causes for Alpha Interferon Activity Increased, Fibromyalgia

  • Chronic Fatigue Syndrome

    Van Houdenhove B, Luyten P: Stress, depression and fibromyalgia. Acta Neurol Belg 2006, 106:149–156. PubMed Google Scholar 31.[doi.org] , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] Hudson JI, Pope HG: Fibromyalgia and psychopathology: is fibromyalgia a form of “affective spectrum disorder.” J Rheumatol 1989, 16 :15–22. Google Scholar 91.[doi.org]

  • Infectious Mononucleosis

    Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] In EBV infection levels of abnormal circulating Th1 lymphocytes are increased, leading to activation of cell-mediated immunity.[omicsonline.org]

  • Systemic Lupus Erythematosus

    The scores in all eight domains of the SF-36 were lower in SLE patients with fibromyalgia than in patients without fibromyalgia and HCs.[ncbi.nlm.nih.gov] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] In fact, lupus is sometimes called "the great imitator" because its symptoms are often like the symptoms of rheumatoid arthritis, blood disorders, fibromyalgia, diabetes,[web.archive.org]

  • Lupus Erythematosus

    The scores in all eight domains of the SF-36 were lower in SLE patients with fibromyalgia than in patients without fibromyalgia and HCs.[ncbi.nlm.nih.gov] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] Ablin, Hagit Cohen, Lily Neumann, Zeev Kaplan and Dan Buskila, Coping styles in fibromyalgia: effect of co-morbid posttraumatic stress disorder, Rheumatology International[doi.org]

  • Drug-induced Lupus Erythematosus

    Secondary fibromyalgia is common. Raynaud's phenomenon occurs in about one fifth of patients but is often mild. Mucocutaneous: Photosensitivity rash.[patient.info] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] Other diseases and conditions that can accompany lupus include fibromyalgia, coronary heart disease, nonbacterial valvular heart disease, pancreatitis, esophagus disease with[rxlist.com]

  • Myocarditis

    Spinal nerve problem Fibromyalgia Chest wall problems Radiculopathy Precordial catch syndrome - another benign and harmless form of a sharp, localized chest pain often mistaken[en.wikipedia.org] The possible modes of action include enhancing natural killer cell activity, inducing production of alpha‐ and gamma‐interferon, improving cardiac microcirculation, and activity[doi.org] There are an increasing number of reports in the medical literature about liver toxicity, renal damage, and even cancer from some Chinese herbal products ( Ishizaki 1996 ;[doi.org]

  • Childhood Dermatomyositis

    His rheumatologist said he has seen a few cases of children with JDM and Fibromyalgia.[globalgenes.org] Activation of dendritic cells with upregulation of genes induced by type-1 interferon (alpha) in muscle and peripheral blood seems to be central to disease pathogenesis.[ncbi.nlm.nih.gov] Dominic was also diagnosed with Fibromyalgia in the fall, which causes him to tire easily and spend time in pain.[globalgenes.org]

  • Local Lupus Erythematosus

    It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[mollysfund.org] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] Concerning other comorbidities not included in the SDI, treatment-required fibromyalgia and arterial hypertension were the most frequent (8.2% and 7.7%, respectively).[journals.plos.org]

  • Chronic Active Hepatitis

    Some patients develop pain in small joints in the body (such as the hand) that may be nearly indistinguishable from symptoms of rheumatoid arthritis, fibromyalgia, or carpal[skylinefamilypractice.net] CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov] At the time of the hemorrhage, plasma-activated complement 5, a known potent intravascular aggregator of granulocytes, increased to 54 ng/ml in one patient and to 29 ng/ml[ncbi.nlm.nih.gov]

  • Waters-West Syndrome

    […] analysis and, preferably, molecular diagnostics since GHB is employed in illicit settings, as well as in an increasing number of clinical situations, including narcolepsy, fibromyalgia[rarediseasesnetwork.org] Laboratory evaluation shows increased alpha-interferon ( IFNA1 ) activity with upregulation of interferon signaling and interferon-stimulated gene expression.[mendelian.co]

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