Create issue ticket

18 Possible Causes for Alpha Interferon Activity Increased, Globulins Increased

  • Infectious Mononucleosis

    Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] , gamma globulin increased less frequently, and beta globulin, which was normal in practically all the cases of infectious mononucleosis, was increased in a considerable number[link.springer.com] […] rate of EBV reactivation after HSCT is expected to increase.[dx.doi.org]

  • Alcoholic Hepatitis

    We analyzed clinical, biological, virological and histological features in two cases where alpha-interferon treatment for HCV-related hepatitis led to a marked increase in[ncbi.nlm.nih.gov] […] serum globulin levels Metabolic Elevated blood ammonia level Hyperglycemia Respiratory alkalosis Hypomagnesemia Hypophosphatemia Hyponatremia Hypokalemia Back to Top Treatment[clevelandclinicmeded.com] […] aminotransferase activities. alpha-interferon as treatment of HCV-related hepatitis seemed to exacerbate acute alcoholic hepatitis despite moderate alcohol consumption.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] […] gamma globulins), cryoglobulins (frequently positive), and direct Comb’s test (frequently positive).[clinicaladvisor.com] Reports pointing to important roles of interferon-alpha, transcription factors, and signaling variations also point to a central role for neutrophils. [21] Genetics There[emedicine.com]

  • Renal Cell Carcinoma

    Beta-D-glucans may promote dendritic cell (DC) maturation; increase interferon gamma (IFN-gamma), tumor necrosis factor alpha (TNF-alpha) and immunoglobulin levels; and may[cancer.gov] […] enhance natural killer (NK) cell activity, potentially boosting anti-tumor host immune responses.[cancer.gov] […] extract A dietary supplement containing an extract of the Basidiomycete fungus Agaricus blazei Murill with potential chemopreventive, antineoplastic and immunopotentiating activities[cancer.gov]

  • Chronic Active Hepatitis B

    CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov] In all patients AST and ALT values returned to normal and there was a fall in serum delta GT and improvement of prothrombin time. an increase of globulins was noted.[ncbi.nlm.nih.gov] The positive anti-HCV antibody common in patients with IACAH is caused by disease related hypergammaglobulinemia and steroid therapy usually leads to decrease in gamma globulin[hepatitiscentral.com]

  • Childhood Dermatomyositis

    Activation of dendritic cells with upregulation of genes induced by type-1 interferon (alpha) in muscle and peripheral blood seems to be central to disease pathogenesis.[ncbi.nlm.nih.gov] Dermatomyositis and polymyositis have been linked to an increased cancer risk. Cancer, if present, generally determines the overall prognosis.[merckmanuals.com] […] dermatomyositis; HLA B8-DRB1*0301 ancestral haplotype is a strong immunogenetic risk factor, and antecedent infections and birth seasonality suggest that environmental stimuli might increase[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis

    CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov] Severe chronic active hepatitis, defined as the presence of a fivefold increase in serum aminotransferases and a twofold rise in gamma globulin for at least 10 weeks, is considered[ncbi.nlm.nih.gov] The positive anti-HCV antibody common in patients with IACAH is caused by disease related hypergammaglobulinemia and steroid therapy usually leads to decrease in gamma globulin[hepatitiscentral.com]

  • Intestinal Tuberculosis

    Expression of growth-related oncogene-alpha was increased in intestinal TB, while expression of interferon-gamma (IFN-) and TLR 4, 5 and 9 was increased in Crohn's disease[ncbi.nlm.nih.gov] Expression of RANTES (regulated upon activation, normal T-cell expressed and secreted) was decreased in Crohn's disease.[ncbi.nlm.nih.gov]

  • Chronic Fatigue Syndrome

    , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] An abnormality of particular interest is reduced sex hormone binding globulin (307).[web.archive.org] […] such as disabling lethargy, myalgias, and cognitive impairment, are similar to the effects observed with high dosage treatments of cytokines including interleukin-2 and alpha[aafp.org]

  • Zinc Deficiency

    Zinc increases the activity of the human cytokine interferon alpha responsible for preventing viral replication.[thetruthaboutcancer.com] The total serum protein concentration and the percentage albumin were normal, while gamma globulin was increased.[ncbi.nlm.nih.gov]

Further symptoms

Similar symptoms