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5,500 Possible Causes for Alpha Interferon Activity Increased, Neutrophil Count Decreased, Thrombocytopenia

  • Infectious Mononucleosis

    They include Granulocytopenia Thrombocytopenia Hemolytic anemia Transient mild granulocytopenia or thrombocytopenia occurs in about 50% of patients; severe cases, associated[merck.com] Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] Corticosteroids may have a role in hastening resolution of some complications, especially upper airway obstruction and possibly immune-mediated anemia and thrombocytopenia[oadoi.org]

  • Systemic Lupus Erythematosus

    Background While thrombopoeitin (TPO) agonists that act to simulate platelet production have been approved for use in steroid-refractory chronic immune thrombocytopenia purpura[ncbi.nlm.nih.gov] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] Normal WBC counts Leukopenia is caused due to decrease in number of WBCs, particularly neutrophils.[news-medical.net]

  • Vitamin B12 Deficiency

    thrombocytopenia were improved by vitamin B12 supplementation alone, with a single session of plasma exchange.[ncbi.nlm.nih.gov] […] lactate dehydrogenase, vasoconstriction, increased platelet aggregation, and abnormal activation of the coagulation followed by microangiopathy as well as neutropenia and thrombocytopenia[ncbi.nlm.nih.gov] […] hypoproliferative megaloblastic anemia with hemolysis (hemoglobin 61g/L, mean corpuscular volume 99fL, reticulocytes 0.8%, haptoglobin undetectable), leukopenia (2.7 109/L), thrombocytopenia[ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Chronic Alcoholism

    Leukopenia and Thrombocytopenia due to direct bone marrow effect, but also from cirrhosis/splenomegaly.[errolozdalga.com] In chronic alcoholism, macrocytosis, thrombocytopenia, prolonged PT, elevated GGT, hyperuricaemia or hypertriglyceridaemia may be found.[rcpa.edu.au] […] continuous Alcoholism, chronic, episodic Cerebral degeneration due to alcoholism Continuous chronic alcoholism Episodic chronic alcoholism Postpartum alcohol dependence Thrombocytopenia[icd10data.com]

    Missing: Alpha Interferon Activity Increased
  • Non-Hodgkin Lymphoma

    In the dose-expansion phase, patients were treated with selinexor at 35 or 60 mg/m 2 The most common grade 3 to 4 drug-related adverse events were thrombocytopenia (47%),[ncbi.nlm.nih.gov] The most common grade 3 adverse events (AEs) were anemia (43%), neutropenia (39%), decreased neutrophil count (32%), febrile neutropenia (31%), decreased white blood cell[onclive.com] Complications Neutropenia, anaemia, thrombocytopenia (secondary to bone marrow infiltration).[patient.info]

    Missing: Alpha Interferon Activity Increased
  • Leukoerythroblastic Anemia

    Acute Erythroblastic Leukemia Anemia, X-Linked, without Thrombocytopenia aplastic anemia Aplastic Anemia, Idiopathic Bone Marrow Failure Syndromes chronic myeloid leukemia[rgd.mcw.edu] THIS IS NOT A TRUE DECREASE BUT RESULTS FROM INCREASED MARGINATION BY NEUTROPHILS.[meddean.luc.edu] […] who presented seven years following apparently successful surgery and adjuvant chemo-radio-therapy, with blood film findings of microangiopathic hemolytic anemia (MAHA), thrombocytopenia[ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Aplastic Anemia

    After the initial appearance of AMI approximately 2 months earlier, he had received conservative treatment/transfusion alone because of severe thrombocytopenia and anemia[ncbi.nlm.nih.gov] The diagnosis usually requires the presence of pancytopenia with a neutrophil count fewer than 1500/ μ L (1.5 10 9 /L), a platelet count fewer than 50,000/ μ L (50 10 9 /L[accessmedicine.mhmedical.com] In women, this can lead to menorrhagia secondary to thrombocytopenia which may require treatment depending on its severity.[ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Leukemia

    Anemia and thrombocytopenia are the major adverse prognostic variables. CLL has no standard staging system.[web.archive.org] […] in the incidence of infection when the neutrophil count increases from less than 0.1 10 9 /L to greater than 0.5 10 9 /L. 11 Although documented infections in HCL patients[bloodjournal.hematologylibrary.org] CASE PRESENTATION: We report a case of a 53 year old patient with T-LGL, Immune-Thrombocytopenia (ITP) and combined antibody deficiency, who presented with fever and reduced[ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Chronic Lymphocytic Leukemia

    Anemia and thrombocytopenia are the major adverse prognostic variables. CLL has no standard staging system.[web.archive.org] : 1500/μL absolute neutrophil count, 100000/μL platelets, 11.0 g/dL hemoglobin or 50% improvement for either of these parameters without transfusions or growth factors.[clinicaltrials.gov] A high lymphocyte count with a low neutrophil count might be caused by lymphoma.[en.wikipedia.org]

    Missing: Alpha Interferon Activity Increased
  • Multiple Myeloma

    KEYWORDS: Multiple myeloma; autoimmun hemolytic anemia; evan s syndrome; thrombocytopenia[ncbi.nlm.nih.gov] […] absolute neutrophil count, decreased phosphorus, anemia, neutropenia, decreased total white blood cell count, decreased platelets, diarrhea, fatigue, thrombocytopenia, pyrexia[investors.amgen.com] Moreover, there was much more largely decreased incidence of grade 3 and higher thrombocytopenia and BIPN in bortezomib SC administration than IV route.[ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased

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