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439 Possible Causes for Alpha Interferon Activity Increased, Patient Appears Chronically Ill

  • Chronic Fatigue Syndrome

    , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] Consistently reported risk factors for poor prognosis are older age, more chronic illness, having a comorbid psychiatric disorder and holding a belief that the illness is[ncbi.nlm.nih.gov] […] such as disabling lethargy, myalgias, and cognitive impairment, are similar to the effects observed with high dosage treatments of cytokines including interleukin-2 and alpha[aafp.org]

  • Systemic Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] Reports pointing to important roles of interferon-alpha, transcription factors, and signaling variations also point to a central role for neutrophils. [21] Genetics There[emedicine.com]

  • Chronic Active Hepatitis B

    CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov] […] of the smaller dose required and the greater increase in life expectancy of children.[ncbi.nlm.nih.gov]

  • Mycobacterium Avium Complex

    Individuals with localized pulmonary MAC infections showed increased activation of monocytes and enhanced monocyte and T-cell tumor necrosis factor alpha (TNF-alpha) production[ncbi.nlm.nih.gov] His physical examination was significant to find an elderly patient with chronic ill dishevelled appearance, using a nasal cannula at 6 L /min.[ijcasereportsandimages.com] Genomic DNA from the individual with the brain MAC infection was studied for gamma interferon (IFN-gamma) receptor mutations.[ncbi.nlm.nih.gov]

  • Intestinal Tuberculosis

    Expression of growth-related oncogene-alpha was increased in intestinal TB, while expression of interferon-gamma (IFN-) and TLR 4, 5 and 9 was increased in Crohn's disease[ncbi.nlm.nih.gov] Expression of RANTES (regulated upon activation, normal T-cell expressed and secreted) was decreased in Crohn's disease.[ncbi.nlm.nih.gov]

  • Substance Abuse Problems

    Abstract Hospital-wide rumors and anecdotal reports had suggested that there was a potentially serious problem of alcohol and drug abuse among the psychiatric patients of this hospital. The authors describe a systematic, evaluative approach which gave direct and detailed information on the nature and extent of[…][ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Chronic Alcoholism

    The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…][ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Iron Deficiency Anemia

    A 19-month-old girl with a history of asthma and atopic dermatitis presented to her pediatrician because of parental concerns of pallor and fatigue. On dietary history, it was discovered that she was a picky eater and consumed 26 oz of homogenous milk daily. Her physical examination was unremarkable aside from[…][ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Diabetes Mellitus

    BACKGROUND: Type 2 Diabetes Mellitus is a serious metabolic disease that is often associated with vascular complications. There are 1.9 million people living with Diabetes in Ethiopia; diabetes mellitus is found to be the ninth leading cause of death related to its complications. Although the rate of vascular[…][ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased
  • Chronic Obstructive Pulmonary Disease

    We report two cases of perioperative rehabilitation for abdominal cancer patients aged 75 years and older with severe chronic obstructive pulmonary disease (COPD). Case 1 was a 75-year-old man with COPD and 52-year history of smoking 30 cigarettes per day. The patient was diagnosed with gastric cancer and[…][ncbi.nlm.nih.gov]

    Missing: Alpha Interferon Activity Increased

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