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27 Possible Causes for Alpha Interferon Activity Increased, Tachycardia

  • Myocarditis

    The possible modes of action include enhancing natural killer cell activity, inducing production of alpha‐ and gamma‐interferon, improving cardiac microcirculation, and activity[doi.org] The most common abnormality seen in myocarditis is sinus tachycardia with non-specific ST segment and T wave changes.[litfl.com] Clinical presentation included: shortness of breath (67%), fever (67%) and tachycardia (58%).[ncbi.nlm.nih.gov]

  • Renal Cell Carcinoma

    Beta-D-glucans may promote dendritic cell (DC) maturation; increase interferon gamma (IFN-gamma), tumor necrosis factor alpha (TNF-alpha) and immunoglobulin levels; and may[cancer.gov] At admission she had hypotension, tachycardia, and was febrile.[elsevier.es] […] enhance natural killer (NK) cell activity, potentially boosting anti-tumor host immune responses.[cancer.gov]

  • Alcoholic Hepatitis

    We analyzed clinical, biological, virological and histological features in two cases where alpha-interferon treatment for HCV-related hepatitis led to a marked increase in[ncbi.nlm.nih.gov] […] bowel movements (melena) abnormally dark or light skin redness on feet or hands paleness light-headedness or fainting, especially with upright posture rapid heart rate (tachycardia[ihv.org] 98.9 HR 104 RR 19 BP 117/67 O2 99% RA Gen: Well-appearing obese female in no acute distress HEENT: PERRL, marked scleral icterus, sublingual icterus, MMM, no lesions CV: Tachycardia[ddxof.com]

  • Chronic Fatigue Syndrome

    , increased interferon activity, cytokine levels, lymphocyte cell markers, or natural killer cells.[aafp.org] KEYWORDS: Autoimmune syndrome induced by adjuvants; Chronic fatigue syndrome; Myalgic encephalomyelitis; Postural orthostatic tachycardia syndrome[ncbi.nlm.nih.gov] […] heart rate dynamic response during the head-up tilt test differs between patients with CFS and healthy controls, supporting the increased prevalence of postural orthostatic tachycardia[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org] […] previously healthy 11-month-old girl referred to our hospital because of fever, leukopenia, and elevated C-reactive protein presented to us with disturbance of consciousness, tachycardia[ncbi.nlm.nih.gov] Postural orthostatic tachycardia syndrome Chronic fatigue syndrome Cancers associated with the Epstein-Barr virus include: Burkitt's lymphoma, Hodgkin's lymphoma and lymphomas[en.wikipedia.org]

  • Zinc Deficiency

    Zinc increases the activity of the human cytokine interferon alpha responsible for preventing viral replication.[thetruthaboutcancer.com] In addition, severely anemic subjects had tachycardia, 2 had dependent edema that cleared after treatment with iron, and 1 had edema associated with hypoalbuminemia.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] Syncope subsequently developed during the postpartum period due to frequent nonsustained polymorphic ventricular tachycardia, suggesting lupus myocarditis.[ncbi.nlm.nih.gov] Vital signs were significantly marked by high fever, tachycardia, and accelerated breathing rate of 37 times per minute.[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com] […] relapse, making the use of mechanical valves a potentially more appropriate option. 46 Rhythm and conduction abnormalities are noted in SLE patients, most commonly sinus tachycardia[journals.lww.com] Reports pointing to important roles of interferon-alpha, transcription factors, and signaling variations also point to a central role for neutrophils. [21] Genetics There[emedicine.medscape.com]

  • Idiopathic Recurrent Pericarditis

    Yan B, Ye S, Chen G, Kuang M, Shen N, Chen S: Dysfunctional CD4 ,CD25 regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing[karger.com] […] electrocardiogram shows diffuse, nonspecific, concave, ST segment elevation in all leads except aVR and V1; also PR segment depression is possible in any lead except aVR; sinus tachycardia[pathologyoutlines.com] Therefore, in patients presenting with chest discomfort, dyspnoea, tachycardia or tachypnoea, cardiac tamponade should be suspected when jugular distension, hypotension or[textbookofcardiology.org]

  • Drug-Induced Lupus Erythematosus

    The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com] This results in a disturbance in the membrane potential and leads to a supraventricular tachycardia which induces failure of the pacemaker.[wikivisually.com] Reports pointing to important roles of interferon-alpha, transcription factors, and signaling variations also point to a central role for neutrophils. [21] Genetics There[emedicine.com]

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