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36 Possible Causes for Alpha Interferon Activity Increased, Thrombocytopenia, Weight Loss

  • Infectious Mononucleosis

    They include Granulocytopenia Thrombocytopenia Hemolytic anemia Transient mild granulocytopenia or thrombocytopenia occurs in about 50% of patients; severe cases, associated[merck.com] Loss Surgery) Cancer (Oncology) Cardiovascular Dentistry Dermatology Diabetes Ear, Nose, and Throat (ENT) Endocrinology, Diabetes and Metabolism Eye Care Fertility Center[uhealthsystem.com] Th1 lineage mostly produce type 2 interleukin (IL-2), interferon-gamma (INF-γ) and tumor necrosis factor-alpha (TNF-α).[omicsonline.org]

  • Systemic Lupus Erythematosus

    Background While thrombopoeitin (TPO) agonists that act to simulate platelet production have been approved for use in steroid-refractory chronic immune thrombocytopenia purpura[ncbi.nlm.nih.gov] loss.[ncbi.nlm.nih.gov] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com]

  • HIV Infection

    As part of the work up for thrombocytopenia, a rapid HIV antibody based assay was done and was negative.[ncbi.nlm.nih.gov] loss.[medicinenet.com] […] are not generally increased, although expression of IL-1, IL-2, IL-6, IL-12, and interferon-gamma may be elevated.(112) With administration of antiretroviral therapies, these[hivinsite.ucsf.edu]

  • Lupus Erythematosus

    […] autoimmune thrombocytopenia).[merckmanuals.com] Many patients with active lupus feel poorly in general and complain of fever, weight loss and tiredness.[my.clevelandclinic.org] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com]

  • Drug-Induced Lupus Erythematosus

    In conclusion, physicians should be alert to the possibility of DILE in patients presenting with thrombocytopenia under a capecitabine and bevacizumab chemotherapy regimen[ncbi.nlm.nih.gov] These symptoms include fever, malaise, weight loss, arthritis, arthralgia and myalgia 3.[medsafe.govt.nz] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.com]

  • Chronic Active Hepatitis

    Onset was signalled by an abrupt and dramatic thrombocytopenia, which was also the only laboratory parameter able to monitor treatment and progression of the disease.[ncbi.nlm.nih.gov] A 27-year-old woman, para 0-1-2-1, presented at 36 weeks' gestation with a 2-week history of malaise, nausea, emesis, diarrhea, and an 18-lb weight loss.[ncbi.nlm.nih.gov] CONCLUSIONS: alpha-interferon therapy for patients with chronic active hepatitis B is cost effective. alpha-Interferon is more cost effective in toddlers than adults because[ncbi.nlm.nih.gov]

  • Malignant Angioendotheliomatosis

    Her serum protein normalized; however, extensive edema persisted, and the degree of thrombocytopenia became severe.[myslide.es] The general signs and symptoms may include weight loss, fatigue, headaches, and frequent infections.[dovemed.com] The generation of polyclonal T-cell cytolytic activity is impaired. Helper (CD4 ) T cells are increased. A lack of immune tolerance is observed in animal lupus models.[emedicine.medscape.com]

  • Alcoholic Hepatitis

    These findings suggest that PAIgG may have been involved in the development of thrombocytopenia in this patient.[ncbi.nlm.nih.gov] When the condition takes a severe turn, the symptoms include loss of appetite, undue fatigue, weight loss due to malnutrition, nausea accompanied by vomiting, fever, confusion[symptoma.com] We analyzed clinical, biological, virological and histological features in two cases where alpha-interferon treatment for HCV-related hepatitis led to a marked increase in[ncbi.nlm.nih.gov]

  • Renal Cell Carcinoma

    Grade 3 or 4 events were for hand-foot syndrome 16%, thrombocytopenia 16% and stomatitis 10% ( 3 ). 3.1.[intjcancermanag.com] I thought the weight loss was stress from the move. I was shocked when they said it was kidney cancer.[votrient.com] Beta-D-glucans may promote dendritic cell (DC) maturation; increase interferon gamma (IFN-gamma), tumor necrosis factor alpha (TNF-alpha) and immunoglobulin levels; and may[cancer.gov]

  • Mycobacterium Avium Complex

    Both leukocytopenia and thrombocytopenia had been noted in the patient's 19-year-old younger brother, who had been living in the same home 5 years earlier, and for whom a[ncbi.nlm.nih.gov] ., Ph.D. 5 Citing Articles Figure 1 An 81-year-old woman was admitted with weight loss (18 kg in 27 months), hemoptysis, and tubular and diffuse granular shadows on her chest[doi.org] Individuals with localized pulmonary MAC infections showed increased activation of monocytes and enhanced monocyte and T-cell tumor necrosis factor alpha (TNF-alpha) production[ncbi.nlm.nih.gov]

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