Alphavirus: Causes & Reasons

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Possible Causes for alphavirus

Viral Arthritis

ENDS About Ross River Virus and Chikungunya Virus Ross River virus is a mosquito-transmitted alphavirus that causes epidemic polyarthritis and bone pain. [scimex.org]

KEYWORDS: Arthritis; alphavirus; arthralgia; hepatitis; parvovirus B19 [ncbi.nlm.nih.gov]

In PNAS, Chen et al. ( 3 ) present evidence that joint pain and associated symptoms of arthritogenic alphavirus infection (in this case a mouse model of RRV) are strikingly [pnas.org]

Ross River Fever

However, the role of complement in alphavirus pathogenesis is less clear. [jvi.asm.org]

Mosquito-borne viral fever [DS: H00382 ] Arthropod-borne viral fever [DS: H00383 ] Description Ross River fever is an infectious disease caused by Ross River virus (RRV), an alphavirus [genome.jp]

In mice, complement has been shown to limit the growth and spread of the Sindbis group alphavirus AR339 ( 20, 22 ). [jvi.asm.org]

Eastern Equine Encephalitis

Rainbow trout sleeping disease virus is an atypical alphavirus. [ncbi.nlm.nih.gov]

We discuss plausible mechanisms as well the potential utility of our LANAC formulation as a pan-alphavirus vaccine. [ncbi.nlm.nih.gov]

KEYWORDS: EEEV; VEEV; alphavirus; live attenuated vaccine; rational design; virulence mechanisms [ncbi.nlm.nih.gov]

Sindbis Virus Infection

J. 2008; 5: 108 A structural and functional perspective of alphavirus replication and assembly Joyce Jose, Jonathan E. Snyder, Richard J. [viralzone.expasy.org]

BACKGROUND: Sindbis virus (SINV) is a mosquito-borne alphavirus found in Eurasia, Africa, and Oceania. [ncbi.nlm.nih.gov]

BACKGROUND: Sindbis virus (SINV) is an arthropod-borne alphavirus that causes rash and arthritis. [ncbi.nlm.nih.gov]

Barmah Forest Virus Infection

Abstract Barmah Forest virus is a mosquito-borne agent (alphavirus) reported to cause both clinical and subclinical infections in New South Wales. [ncbi.nlm.nih.gov]

Diseases and Microbiology Laboratory Services, Westmead, NSW, Australia. linda.hueston@swahs.health.nsw.gov.au Abstract Barmah Forest virus (BFV) is a mosquito borne ( ) ssRNA alphavirus [ncbi.nlm.nih.gov]

Abstract Barmah Forest virus (BFV) is a mosquito borne ( ) ssRNA alphavirus found only in Australia. [cureus.com]

Venezuelan Equine Encephalitis

Abstract Venezuelan equine encephalitis virus (VEEV) is an Alphavirus from the family Togaviridae that causes epizootic outbreaks in equids and humans in Central and South [ncbi.nlm.nih.gov]

Informação e Conhecimento para a Saúde Evolution and spread of Venezuelan equine encephalitis complex alphavirus in the Americas. [pesquisa.bvsalud.org]

Annu Rev Entomol 49 : 141 – 174 Wengler G ( 2009 ) The regulation of disassembly of alphavirus cores. [emboj.embopress.org]

Chikungunya

The T cell immune T cell response to Chikungunya virus (CHIKV), a mosquito-borne Alphavirus of the Togaviridae family responsible for severe musculoskeletal disorders, has [ncbi.nlm.nih.gov]

(Genus) Chikungunya virus (Species) Status accepted Rank Species Parent Alphavirus Fossil range recent only Original description Not documented Taxonomic citation IRMNG [irmng.org]

Immunization with alphavirus VLP vaccines represents a strategy to contain the spread of CHIKV and related pathogenic viruses in humans. [ncbi.nlm.nih.gov]

Western Equine Encephalomyelitis

Abstract The decrease in western equine encephalomyelitis virus (WEEV; Togaviridae, Alphavirus) activity in North America over the past 20-30 years has prompted research to [ncbi.nlm.nih.gov]

PDF - Published Version See Usage Policy. 397Kb Use this Persistent URL to link to this item: Abstract Western equine encephalomyelitis (WEE) virus (Togaviridae: Alphavirus [authors.library.caltech.edu]

Eastern equine encephalitis virus (EEEV) and Western equine encephalitis virus (WEEV) are in the same family Togaviridae, genus Alphavirus. [dhs.wisconsin.gov]

Mayaro-Semliki Forest Virus Disease

Chikungunya virus (CHIKV) is a RNA virus that belongs to the alphavirus genus of the family Togaviridae. [hset.bio-med.ch]

Treatment of alphavirus infections involves mainly supportive therapy measures. [web.stanford.edu]

It is only known to circulate in tropical South America. [1] Virology [ edit ] Mayaro Virus has a structure similar to other Alphavirus. [en.wikipedia.org]

Viral Disease

KEYWORDS: O’nyong-nyong; alphavirus; chikungunya; epidemiology [ncbi.nlm.nih.gov]

Abstract O'nyong nyong virus (ONNV), a mosquito-borne Alphavirus, is primarily transmitted through the bite of Anopheles funestus and Anopheles gambiae mosquitoes, which are [ncbi.nlm.nih.gov]

Polyarthritis

This condition is termed alphavirus polyarthritis syndrome. [en.wikipedia.org]

Hence this condition is called alphavirus polyarthritis syndrome. [byjus.com]

Alphavirus Polyarthritis caused by alphavirus is called “ alphavirus polyarthritis syndrome “. [healthglimmer.com]

Arboviral Infection

O'nyong-nyong virus [GN: T40027 ] ( ssRNA alphavirus) Mayaro virus [GN: T40032 ] ( ssRNA alphavirus) Ross River virus [GN: T40071 ] ( ssRNA alphavirus) Rift Valley fever [genome.jp]

The Arboviruses that cause encephalitis come from three different virus families: Flaviviridae(genus Alphavirus), Togaviridae, and Bunyaviridae. [austincc.edu]

Chikungunya is a re-emerging alphavirus causing massive epidemics in Africa, in the Indian Ocean, and Southeast Asia. [clinicaltrials.gov]

Arbovirus Encephalitis

The major causes of arbovirus encephalitis include the members of the viral families alphavirus (causing Eastern equine encephalitis, Western equine encephalitis, and Venezuelan [medical-dictionary.thefreedictionary.com]

[…] disease or RRV polyarthralgia Alphavirus Barmah Forest virus BFV Use BFV followed by a description of the illness, eg BFV disease or BFV polyarthralgia Alphavirus Chikungunya [health.gov.au]

These arboviruses are enveloped RNA viruses from different families: Togaviridae (genus Alphavirus ), Flaviviridae (genus Flavivirus ), Bunyaviridae (genus Bunyavirus ), and [emedicine.medscape.com]

Acute Respiratory Infection

In addition to dengue fever, about 700 people in Malang had also suffered from Chikungunya, a viral disease, caused by the Alphavirus virus, which is also spread by the Aedes [crofsblogs.typepad.com]

Seronegative Arthritis

An alphavirus, chikungunya virus makes most affected individuals quite ill, and serum IgG and IgM titers persist long after infection. [mdedge.com]

Alphavirus infections generally resolve over three to six months. [uptodate.com]

The diagnosis of alphavirus infection can be made by appropriate serologic testing in travelers from endemic areas with persistent arthritic symptoms. [uptodate.com]

Influenza

[…] sandfly fever and Punta Toro); hantaviruses (Maporal, Dobrava, and Prospect Hill); flaviviruses (yellow fever and West Nile); enteroviruses (polio- and rhinoviruses); an alphavirus [ncbi.nlm.nih.gov]

[…] is also active against a number of arena-, bunya- and flaviviruses, both in vitro and in rodent models, and it has shown potent in vitro activity against members of the alphavirus [ncbi.nlm.nih.gov]

Viral Exanthem

Table 3: Arboviruses divided into clinical presentation/syndrome, geographic region, clinical features and current diagnostic test availability Alphaviruses Exanthems in alphavirus [journals.lww.com]

Alphaviruses Exanthems in alphavirus infections may appear anytime during the course of illness. [journals.lww.com]

West Nile Virus

As a part of a study on flavivirus, alphavirus, and parasite exposure in coastal Kenya, we measured neutralizing antibody against DENV and, to evaluate assay specificity, [ncbi.nlm.nih.gov]

West Nile virus (WNV) infection may mimic either dengue (flavivirus) or chikungunya (alphavirus) like illness. [ncbi.nlm.nih.gov]

On the contrary, the rhabdovirus vesicular stomatitis virus and the alphavirus Semliki Forest virus exert little lipid selection when they acquire their envelopes ( 8 ). [doi.org]

Varicella Zoster Virus Encephalitis

Together with herpes simplex viruses (HSV) 1 and 2, it belongs to the alphavirus family of human herpesviruses. [symptoma.com]

Alphavirus and flavivirus were absent. Similar data were obtained in this study, although, enterovirus, alphavirus or flavivirus were not sought. [scielo.org.co]

Carcinomatous Polyarthritis

This condition is termed alphavirus polyarthritis syndrome. [en.wikipedia.org]

[…] often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus but can also be caused by infection with an alphavirus [en.wikipedia.org]

Alphavirus Polyarthritis Syndrome has an incubation period of 3–21 days, depending on the specific virus, with either a gradual or sudden onset of fever, arthralgias, headache [en.wikipedia.org]

Viral Pleurisy

Approximately five to six types of alphavirus infection cause rheumatic symptoms and fever as major features; all are mosquito-borne. [emedicine.medscape.com]

Alphaviruses may disrupt bone homeostasis, and osteoblasts may contribute to alphavirus-induced arthritis by regulating IL-6 and contribute to bone loss by disrupting the [emedicine.medscape.com]

Pacific islands Mayaro virus – South America Sindbis virus – Europe, Asia, Africa, Australia, and Philippines Barmah Forest virus – Australia Chen and colleagues found that alphavirus [emedicine.medscape.com]

Rubella-Associated Arthritis

The other genus in the family of Togaviridae is Alphavirus. [asmscience.org]

Symptoms common to all alphavirus infections include rhinorrhoea, sore throat, marked lethargy and backache. [antimicrobe.org]

Alphaviruses Diagnosis of alphavirus infection is confirmed by specific serology results. [emedicine.medscape.com]

Marburg Virus Disease

[…] guinea pigs with killed MBGV, live attenuated MBGV, soluble MBGV-GP expressed by baculovirus recombinants, MBGV-GP delivered as a DNA vaccine, or MBGV-GP delivered via an alphavirus [ncbi.nlm.nih.gov]

ICD-10-CM B33.8 Other specified viral diseases Approximate Synonyms Acute infectious lymphocytosis Cervical myalgia, epidemic Disease due to Alpharetrovirus Disease due to Alphavirus [icd9data.com]

Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates. [doi.org]

Postviral Syndrome

Approximately five to six types of alphavirus infection cause rheumatic symptoms and fever as major features; all are mosquito-borne. [emedicine.medscape.com]

Alphaviruses may disrupt bone homeostasis, and osteoblasts may contribute to alphavirus-induced arthritis by regulating IL-6 and contribute to bone loss by disrupting the [emedicine.medscape.com]

Bed Bug Infestation

Persistence of Buggy Creek virus (Togaviridae, Alphavirus) for two years in unfed swallow bugs (Hemiptera: Cimicidae: Oeciacus vicarius). J. Med. [ncbi.nlm.nih.gov]

Stone Lakes virus (family Togaviridae, genus Alphavirus), a variant of Fort Morgan virus isolated from swallow bugs (Hemiptera: Cimicidae) west of the Continental Divide. [ncbi.nlm.nih.gov]

Meningitis

Togavirus Rubella virus Flavivirus West Nile virus Japanese encephalitis virus St Louis encephalitis virus Bunyavirus California encephalitis virus La Crosse encephalitis virus Alphavirus [emedicine.com]

Post Viral Asthenia

Approximately five to six types of alphavirus infection cause rheumatic symptoms and fever as major features; all are mosquito-borne. [emedicine.medscape.com]

Joint pain is reported in infections with hepatitis A virus (HAV), hepatitis B virus (HBV), alphavirus, dengue virus, Epstein-Barr virus, and others. [rheumatologyadvisor.com]

Alphaviruses may disrupt bone homeostasis, and osteoblasts may contribute to alphavirus-induced arthritis by regulating IL-6 and contribute to bone loss by disrupting the [emedicine.medscape.com]

Rift Valley Fever

The observations of VT for other arboviruses in the genera Alphavirus, Flavivirus and Orthobunyavirus are discussed within the context of RVFV. [jgv.microbiologyresearch.org]

This would be consistent with alphavirus assemblies, in which the fusion protein E1 is covered by E2 ( 33, 34 ). Fig. 4. [doi.org]

The overall configuration bears strong similarity ( 22 ) to alphavirus E1 proteins and flavivirus E proteins ( Fig. 1 C and D ) despite the highly divergent sequence of RVFV [doi.org]

Astrovirus

Alphavirus RNA synthesis and non-structural protein functions. J Gen Virol. 2015;96(9):2483–500. [doi.org]

Composition of alphavirus-like replication complexes: involvement of virus and host encoded proteins. Arch Virol. 2002;147(5):875–98. [doi.org]

Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses. Biology Direct. 2015;10:16. [doi.org]

Pruritic Rash

Chikungunya fever is a mosquito-borne illness caused by chikungunya virus (CHIKV), an alphavirus that is part of the Togaviridae family. [academic.oup.com]