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22 Possible Causes for Altered Mental Status, Generalized Dystonia, Lower Motor Neuron Signs - Later

  • Paraneoplastic Syndrome

    Movement disorders include oro-lingual-facial dyskinesias, generalized chorea, oculogyric crisis, dystonia, and rigidity.[clinlabnavigator.com] […] sclerosis Definition / general: Rarely caused by breast cancer 50% develop lower motor neuron signs eventually Retinal degeneration Definition / general: Destruction of photoreceptors[pathologyoutlines.com] mental status to coma.[doi.org]

  • Brain Compression

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Metabolic encephalopathy is the common nonmetastatic cause of altered mental status in cancer patients.[aafp.org] Note motion artifact from altered mental status.[webeye.ophth.uiowa.edu]

  • Subacute Combined Degeneration of Spinal Cord

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Lateral sclerosis is the loss of axons in the lateral columns of the spinal cord (the upper motor neurons of the corticospinal tracts).[britannica.com] ALS, or Lou Gehrig disease, is characterized by muscle wasting due to loss of the ventral-horn cells (the lower motor neurons).[britannica.com]

  • Extrapyramidal Disorder

    In a majority of individuals, dystonia becomes generalized and disabling ( Figure 1B, 1F, 1H ). Progressive dystonia of the trunk may lead to severe dystonic scoliosis.[ncbi.nlm.nih.gov] Clinical phenomena usually consist of a mixture of lower and upper motor neuron signs, dementia, and urinary dysfunction.[jnnp.bmj.com] mental status.[medbullets.com]

  • Constitutional Anemia due to Iron Metabolism Disorder

    [primary TOR1A (DYT1)] G31.82 Leigh's disease G40.301 - G40.319 Generalized idiopathic epilepsy and epileptic syndromes [nonspecific myoclonic epileptic seizures (MERRF)[aetna.com] Often (but not always), patients will have other cardinal features of the disease, including thrombocytopenia, altered mental status, and renal insufficiency.[emedicine.medscape.com] Familial Amyotrophic Lateral Sclerosis (SOD1 Mutation) Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving both the upper motor neurons[aetna.com]

  • Meningeal Disorder

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Metabolic encephalopathy is the common nonmetastatic cause of altered mental status in cancer patients.[aafp.org] […] is bent forwards, backwards, or to the side that are present in normal infants and are incorporated in many bodily movements of normal children and adults tonic seizure generalized[strokecenter.org]

  • Ischemic Peripheral Neuropathy

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] Most importantly, any patient who develops acute severe headache, acute severe hypertension, intractable nausea and vomiting, altered mental status or other evidence of neurologic[cdemcurriculum.com] Lateral sclerosis is the loss of axons in the lateral columns of the spinal cord (the upper motor neurons of the corticospinal tracts).[britannica.com]

  • Spinal Demyelination

    Generalized dystonia (e.g., dystonia musculorum deformans) is an inherited condition in which persistent and often painful twisting and writhing movements of any muscle group[britannica.com] mental status/encephalopathy Hemiparesis Hemisensory loss Reduced visual acuity or blindness in the affected eye(s) Cerebellar findings (ataxia, dysdiadochokinesia) Often[clinicaladvisor.com] Lateral sclerosis is the loss of axons in the lateral columns of the spinal cord (the upper motor neurons of the corticospinal tracts).[britannica.com]

  • Amyotrophic Lateral Sclerosis

    It can be localized to a certain group of muscles or can be generalized (180).[functionalneurology.com] It is one of many motor neuron diseases, but what makes it stand out is that it presents with both upper and lower motor neuron signs.[symptoma.com] Paramedics bring a 26-year-old man to the ED with acute-onset altered mental status. He has a history of back pain. An open, unlabeled pillbox was found.[emedicine.medscape.com]

  • Ataxia-Oculomotor Apraxia Syndrome

    . : Severe generalized dystonia as a presentation of a patient with aprataxin gene mutation . Mov Disord 2003, 18 :1198–1200. PubMed CrossRef Google Scholar 35.[link.springer.com] Patient II-4 of family 3 presents, in addition to the clinical picture of AOA2, an unusual severe lower motor neuron impairment.[jamanetwork.com] Children present with altered mental status, ataxia and behavior changes.[lecturio.com]

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