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43 Possible Causes for Altered Mental Status, Rapid Progression to Disability

  • Alzheimer Disease

    Our findings may reflect the presence of greater comorbidity leading to earlier death among men than among women with AD, 57 or a more rapid progression of AD in women. 58[dx.doi.org] - 61 The inherent survival advantage of women in general may lead women to live longer, tolerating greater disability, than men.[dx.doi.org]

  • Transient Ischemic Attack

    Rapid recognition and response is essential to reduce the risk of disability and death. 4,8,10 As the American Heart Association/American Stroke Association (AHA/ASA) points[journals.lww.com] These include, but are not limited to: Laboratory tests should focus on ruling out metabolic conditions that may mimic TIA (e.g. hypoglycemia causing altered mental status[en.wikipedia.org] […] similar episodes, and absence of nonspecific symptoms such as gastrointestinal distress, chest pain, or shortness of breath. 1 No one can predict which TIAs are likely to progress[journals.lww.com]

  • Primary Progressive Multiple Sclerosis

    Although progression is more rapid, age-related disability milestones are identical to relapsing-onset disease.[ncbi.nlm.nih.gov] A previous analysis of the British Columbia MS database challenged the view that disability progression is rapid in PPMS, but identified few predictors of disease progression[ncbi.nlm.nih.gov] , for which prognosis is considered as poor due to the relatively rapid development of advanced disability as compared with RRMS.[globenewswire.com]

  • Paraneoplastic Syndrome

    progression to severe disability and the absence of regeneration in a sural nerve biopsy.[doi.org] mental status to coma.[doi.org] Rosengart, A young man with altered mental status and new-onset seizures, Journal of the American Academy of Physician Assistants, 26, 10, (34), (2013).[doi.org]

  • Multiple Sclerosis

    progression of disability, more frequent relapses, and worse postrelapse recoveries.[dx.doi.org] CASE REPORT We report on a case of a 45-year-old female multiple sclerosis (MS) patient presenting with acute onset short-term memory loss, altered mental status, inflammatory[ncbi.nlm.nih.gov] Paramedics bring a 26-year-old man to the ED with acute-onset altered mental status. He has a history of back pain. An open, unlabeled pillbox was found.[emedicine.medscape.com]

  • CINCA Syndrome

    Pediatricians should be aware of this rare condition in order to prevent progression to irreversible organ damage and disability.[docksci.com] Two patients had clinical evidence of CNS involvement with irritability and altered mental status.[adc.bmj.com] Rapid clinical response to IL-1 International Journal of Rheumatic Diseases 2014; 17: 346–348 blocking therapy has made it imperative to treat patients early and aggressively[docksci.com]

  • Creutzfeldt Jakob Disease

    The condition is hard to link to a specific symptom, although it is mistaken for CJD because of rapid progression of disability and its common involvement of visual pathways[doi.org] .— Acute cerebellitis is a clinically defined condition most commonly characterized by acute cerebellar ataxia, associated with nausea, headache, and altered mental status[doi.org]

  • Puerperium

    Deterioration Scale (PDS), Interview for Deterioration in Daily Living Activities in Dementia (IDDD), Disability Assessment in Dementia Scale (DADS), Functional Assessment[catsclem.nl] mental status.[contemporaryobgyn.net] Seizures, focal neurologic deficits, altered mental status, and coma are the most common causes of mortality in eclampsia.[ajronline.org]

  • Spinal Demyelination

    progression to disability within several days to weeks, culminating in the need for hospital admission and aggressive therapy for an acute attack. 5 Among fulminant demyelinating[nature.com] mental status/encephalopathy Hemiparesis Hemisensory loss Reduced visual acuity or blindness in the affected eye(s) Cerebellar findings (ataxia, dysdiadochokinesia) Often[clinicaladvisor.com] However, the higher incidence of spinal cord lesions often found in primary progressive multiple sclerosis (PPMS) does contribute to a more rapid development of disability[healthcentral.com]

  • Myelitis

    […] one third remain severely disabled Poor prognostic indicators rapid progression of symptoms back pain spinal shock absent central conduction on somatosensory evoked potential[lifeinthefastlane.com] Bickerstaff’s brainstem encephalitis (BBE) is a rare, autoimmune mediated inflammatory condition, which is associated with opthalmoplegia, altered mental status and ataxia[nature.com] Progression ; Transverse myelitis (TM) The progression is rapid • time to maximal disability is more than 4 hr and fewer than 21 days. A.[slideshare.net]

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