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106 Possible Causes for Altered T-Cell Regulation

  • Hypersensitivity

    It is postulated that these infections exert their effect through critically altering T-helper (Th)1/Th2 regulation, which is supported by the examination of the cytokine[ncbi.nlm.nih.gov] Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J Clin Invest . 2001 Dec. 108(12):1865-73. [Medline] .[emedicine.medscape.com] […] profiles of cord mononuclear cells when exposed to gastrointestinal flora and, furthermore, emerging evidence on the benefits of probiotics on symptoms of atopic dermatitis[ncbi.nlm.nih.gov]

  • Toxoplasmosis

    […] of the cell cycle and opposing regulation of cell growth and death.[nature.com] When we place our findings presented herein in the broad context of diseases and mechanisms of specific diseases, our work indicates T. gondii can cause a dominant alteration[nature.com]

  • Liver Cirrhosis

    On the other hand, natural killer T (NKT) cells, a T cell subset that co-expresses the NK cell marker, regulate immune system by inducing apoptosis of altered hepatocytes.[dx.doi.org]

  • Endometriosis

    […] network of transcriptional regulators for interpreting local metabolic changes resulting in subtype differentiation. 152 T-cell differentiation is altered toward an inflammatory[dx.doi.org] It is noteworthy that nuclear receptors such as RXR and PPAR-γ heterodimerize and it seems that these dimers provide cells such as macrophages with a coordinated and inter-related[dx.doi.org]

  • Chronic Fatigue Syndrome

    T cells.[doi.org] Duddy ME, Alter A, Bar-Or A (2004) Distinct profiles of human B cell effector cytokines: a role in immune regulation? J Immunol 172:3422–3427 PubMed Google Scholar 212.[doi.org] Harris DP, Haynes L, Sayles PC, Duso DK, Eaton SM, Lepak NM, Johnson LL, Swain SL, Lund FE (2000) Reciprocal regulation of polarized cytokine production by effector B and[doi.org]

  • Demyelinating Disease

    We recently described that alteration of the gut microflora can affect a population of Foxp3( )T(reg) cells that regulate demyelination in experimental autoimmune encephalomyelitis[ncbi.nlm.nih.gov]

  • Basal Cell Carcinoma

    For example, in the erythroderma (reddening of the skin) associated with advanced cutaneous T-cell lymphoma, alterations in the regulations of body temperature can result[cancer.gov] In adaptive immunity, antigen-presenting cells engender T-cell responses consisting of increased levels of TH1, TH2, or TH17 cells.[ 9 ] In innate immunity, the immune system[cancer.gov] These functions can be aberrantly regulated in cancer.[cancer.gov]

  • Ovarian Cystic Teratoma

    Malignant transformation of mature cystic teratoma to squamous cell carcinoma involves altered expression of p53- and p16/Rb-dependent cell cycle regulator proteins.[bmccancer.biomedcentral.com] Yoshioka T, Tanaka T. Immunohistochemical and molecular studies on malignant transformation in mature cystic teratoma of the ovary.[bmccancer.biomedcentral.com]

  • Adenomyosis Uteri

    […] network of transcriptional regulators for interpreting local metabolic changes resulting in subtype differentiation. 152 T-cell differentiation is altered toward an inflammatory[doi.org] It is noteworthy that nuclear receptors such as RXR and PPAR-γ heterodimerize and it seems that these dimers provide cells such as macrophages with a coordinated and inter-related[doi.org]

  • Celiac Disease

    McKay FC, Swain LI, Schibeci SD, Rubio JP, Kilpatrick TJ, Heard RN, Stewart GJ, Booth DR (2008) CD127 immunophenotyping suggests altered CD4 T cell regulation in primary progressive[dx.doi.org]

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