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2 Possible Causes for Ambulation Due to Muscle Weakness Impaired

  • Hypophosphatasia

    […] of whom had skeletal involvement, muscle weakness, and/or difficulties with ambulation.[insight.jci.org] In this study, asfotase alfa was administered for the first time to older children (6–12 years old) impaired by the infantile and childhood forms of hypophosphatasia, all[insight.jci.org] Due to the rarity of hypophosphatasia ( 1 ), a concurrent control group was not possible, but evaluation of the primary outcome objective ( 12 ) concerning the radiographic[insight.jci.org]

  • Miyoshi Muscular Dystrophy Type 3

    All the patients are able to ambulate independently, with steppage observed in 50% of cases due to weakness and atrophy in anterior muscle compartments of the lower leg or[frontiersin.org] […] diffuse impairment of all of the calf muscles.[frontiersin.org]

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