Create issue ticket

91 Possible Causes for Ammonia Increased, Respiratory Alkalosis

  • Urea Cycle Disorder

    An increased level of ammonia in the bloodstream, or hyperammonemia, is a symptom associated with metabolic disorders referred to as inborn errors of metabolism.[] […] distress * Respiratory alkalosis * Increased blood ammonia level * Failure to thrive * Constant infant crying * Agitation * Hyperactive behavior * Self-injury * Screaming[] Soon after, seizures, hypotonia (poor muscle tone, floppiness), respiratory distress (respiratory alkalosis), and coma may occur.[]

  • Propionic Acidemia

    OBJECTIVES: The objective of this study was to determine whether N-carbamylglutamate (NCG) reduces plasma levels of ammonia and glutamine and increases the rate of ureagenesis[] While hyperventilation may provoke respiratory alkalosis, most patients present with metabolic acidosis due to further metabolic disturbances.[] Alkalosis Urea cycle disorders Metabolic Profiles Organic and Amino Acid Disorders Metabolic Profiles Organic and Amino Acid Disorders Newborn screening is available dependent[]

  • Carbamoyl Phosphate Synthetase Deficiency

    They may rapidly progress to respiratory alkalosis as ammonia increases with cerebral edema, seizures, loss of reflexes, hypothermia, apnea, and coma.[] Neonatal onset results in clinical features that include irritability, vomiting, lethargy, seizures, neonatal hypotonia; respiratory alkalosis; hyperammonemia; coma, and death[] Biochemically, a highly elevated blood ammonia level was found together with an increased plasma level of the amino acids mainly involved in ammonia detoxication.[]

  • Psychogenic Hyperventilation

    Causes of Respiratory Alkalosis 1.[] ammonia and glutamine, and hypoxemia from the formation of small intrapulmonary shunts (ie: hepatopulmonary syndrome) - increased respiratory drive Neurologic/Psychogenic[] (metabolic acidosis and respiratory alkalosis).[]

  • Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

    Blood ammonia increased from high normal values to 975, 990, and 750 mumol/liter (normal less than 70) and urinary orotic acid from trace to 539, 494, and 1296 mumol/mmol[] The neonatal presentation usually begins a few days after birth with lethargy, somnolence, refusal to feed, vomiting, tachypnea with respiratory alkalosis, and/or seizures[] Increased levels of ammonia, ornithine and homocitrulline were demonstrated in blood and cerebrospinal fluid.[]

  • Alcoholic Liver Disease

    alkalosis Hypomagnesemia Hypophosphatemia Hyponatremia Hypokalemia Back to Top Treatment The foundation of therapy for ALD is abstinence.[] The main factor involved in causing the encephalopathy is an increase in ammonia levels in the brain.[] Examples include: Hepatic encephalopathy: Increased ammonia levels due to the liver's inability to process and metabolize proteins in the diet can cause confusion, lethargy[]

  • Acute Liver Failure

    These substances include false neurotransmitters, ammonia, increased gamma-aminobutyric acid receptor activity, and increased circulating levels of endogenous benzodiazepine-like[] Metabolic: Metabolic and respiratory alkalosis may occur early. If shock develops, metabolic acidosis can supervene.[] To eliminate the source of increased ammonia, you’ll likely administer lactulose, a cathartic that will increase bowel movements.[]

  • Reye Syndrome

    Signs of metabolic derangement include elevated serum amino acid levels, acid-base disturbances (usually with hyperventilation, mixed respiratory alkalosis–metabolic acidosis[] The coma deepens even further, seizures develop, respiratory failure occurs, the blood level of ammonia increases, and death generally ensues.[] An initial metabolic acidosis is associated with a compensatory respiratory alkalosis (1,3). The EEG shows diffuse arrhythmic delta activity (1).[]

  • Acidosis

    The production of IMP results from an increased activity of the AMP deaminase reaction, which is activated by acidosis and produces IMP and ammonia (NH 4 ); AMP H « IMP NH[] […] patients who have respiratory alkalosis, the tidal volume and/or respiratory rate may need to be decreased.[] Renal ammonia genesis: Ammonium ions (NH4 ) are produced in the proximal tubule from glutamine metabolism.[]

  • Hyperammonemia Type 3

    As has been indicated above, the central nervous system is most sensitive to increased concentrations of ammonia.[] The presence of respiratory alkalosis in a sick, hyperammonemic neonate or infant is an indicator of an underlying urea cycle defect since it is an uncommon finding in an[] Ammonia levels may be factitiously increased if the tourniquet is too tight for a long period.[]

Further symptoms

Similar symptoms