Amylase Increased: Causes & Reasons

Possible Causes for Amylase Increased

In clinical practice, patients showing increased postoperative systemic amylase concentrations appear to frequently develop POPF. [ncbi.nlm.nih.gov]

On postoperative day (POD) 7, the drain amylase level increased up to 37,460 IU/l. Computed tomography (CT) revealed peripancreatic fluid collections. [ncbi.nlm.nih.gov]

One patient had an asymptomatic, self-limiting (48 hours) increase in serum amylase and lipase after injection. [ncbi.nlm.nih.gov]

Pancreatic Injury

However, when subgroups of patients were studied, the frequency of increased amylase levels decreased significantly in patients with chronic obstructive pancreatitis and in [ncbi.nlm.nih.gov]

In IV and IG groups, serum amylase was increased without morphological signs of AP compared with healthy controls. [ncbi.nlm.nih.gov]

amylase or lipase levels resulted in substantial misclassification of disease. [nejm.org]

Acute Pancreatitis

Lab Increased amylase, increased lipase. Management Supportive bowel rest with parenteral nutrition. [medical-dictionary.thefreedictionary.com]

The combination of lipase and amylase did not increase diagnostic accuracy. Serum lipase is recommended for diagnosis of AP, both early and late in the disease. [ncbi.nlm.nih.gov]

Urine amylase: In the same way, amylase excretion in the urine is also evident. Serum lipase: An increase in serum lipase correlates well with the disease. [symptoma.com]

Pancreatitis

These include: Increased blood amylase level Increased serum blood lipase level (a more specific indicator of pancreatitis) Increased urine amylase level Other blood tests [pennmedicine.org]

Our meta-analysis has demonstrated that both CTLA-4 inhibitors alone and combination treatment of nivolumab and ipilimumab could increase the risk of amylase or lipase elevation [ncbi.nlm.nih.gov]

These tests are: Serum amylase. An increase of amylase in the blood usually indicates pancreatitis. Serum lipase. [healthlinkbc.ca]

Chronic Pancreatitis

In further confirmation of the plasticity of ASCs, ASCs co-cultured with acinar cells in a Transwell system differentiated into amylase + cells with increased expression of [ncbi.nlm.nih.gov]

[…] serum amylase level Increased serum lipase level Serum trypsinogen Tests that may show the cause of pancreatitis include: Serum IgG4 (for diagnosing autoimmune pancreatitis [nlm.nih.gov]

[…] amounts are normal Diarrhea, nausea, and vomiting Fatty or oily stools Pale or clay-colored stools Exams and Tests Tests to diagnose pancreatitis include: Fecal fat test Increased [ufhealth.org]

Mumps

Increased total activity of serum amylase in 79% of patients was due to increased S-type amylase. [ncbi.nlm.nih.gov]

One or both may also be requested when a doctor wants to monitor a patient to find out whether treatment is working and whether amylase levels are increasing or decreasing [web.archive.org]

However, in 39% of patients there was also a markedly increased P-type serum amylase. [ncbi.nlm.nih.gov]

Macroamylasemia

Serum amylase activity tends to increase within a few hours after the onset of pancreatitis. [clinlabnavigator.com]

Abstract We report hyperamylasemia, macroamylasemia, and a markedly increased amylase clearance/creatinine clearance ratio in a patient with renal cell carcinoma. [ncbi.nlm.nih.gov]

Amylase increases may occur postoperatively, resulting in increased S-type and P-type isoamylases; however, an increase in salivary amylase is more common. [emedicine.medscape.com]

Biliary Peritonitis

[…] organisms; increased amylase ; increased mononuclear cells and decreased glucose occur in tuberculous peritonitis Leukocytosis – up to 50,000/ul with 80-90% neutrophils ; [diagnose-me.com]

Fasting blood glucose levels and increases in serum amylase, lipase, and glucose levels may be useful, but are usually not apparent until late. [ghrnet.org]

Diagnosis and Tests Laboratory findings: Ascitic fluid – turbid, bloody, may contain fat globules; increased WBC ; Gram's stain and aerobic and anaerobic cultures show multiple [diagnose-me.com]

Acute Alcohol Intoxication

More marked increases, especially if lipase (amylase is less specific) is elevated > 2-fold, suggest bile duct obstruction. [msdmanuals.com]

On the other hand, there are patients, in course of acute cholecystitis, with mild increase of amylase, AST, ALT, bilirubin caused by papillary passage of sludge, pus, and [intechopen.com]

Passage of a stone through the biliary tract increases aminotransferases (ALT, AST). [msdmanuals.com]

Gastroduodenal Perforation

To determine if there might be significant correlation between an increase in amylase and some of the other factors associated with ulcer perforation, a study was made of [ncbi.nlm.nih.gov]

An elevated serum amylase may accompany duodenal perforation after ERCP and may give the impression of pancreatitis and lead to a delay in diagnosis with an increase in mortality [sites.google.com]

Abstract Elevated serum amylase is a frequent concomitant of perforated gastroduodenal ulcer. [ncbi.nlm.nih.gov]

Sialolithiasis

Blood testing While blood cell count – increased levels suggestive of infection C-Reactive protein increased – sign of infection Serum amylase increased – another sign of [mddk.com]

Tobacco smoking has been shown to result in an increased cytotoxic activity of saliva, a decreased polymorphonuclear phagocytic ability, and a reduction of salivary amylase [jamanetwork.com]

Pancreatic Abscess

[…] in white blood cells (leukocytosis) increased blood levels of amylase (a pancreatic enzyme) severe stomach pain nausea and vomiting Tonsils fever sore throat difficulty speaking [healthline.com]

Plasma lipase levels are increased and are a specific marker of pancreatitis. It differentiates acute pancreatitis from other causes of hyperamylasemia. [ijpmonline.org]

[…] symptoms Mouth floor (a phlegmon here is also called Ludwig’s angina ) dental pain fatigue ear pain confusion swelling of tongue and neck difficulty breathing Pancreas fever increase [healthline.com]

Acute Cholecystitis

More marked increases, especially if lipase (amylase is less specific) is elevated > 3-fold, suggest bile duct obstruction. [msdmanuals.com]

More marked increases, especially if lipase (amylase is less specific) is elevated > 2-fold, suggest bile duct obstruction. [merckmanuals.com]

Passage of a stone through the biliary tract increases aminotransferases (alanine, aspartate). [msdmanuals.com]

Pancreatic Pseudocyst

Laboratory tests showed increased serum and urine amylases. [ncbi.nlm.nih.gov]

Regarding the patient’s clinical course, because his laboratory data at admission showed an increased serum level of amylase (160 U/L, normal range 30-120 U/L), normal white [casereports.in]

[…] in serum amylase levels. [joplink.net]

Endoscopic Retrograde Cholangiopancreatography

Clinical findings, increase serum amylase of threefold or more (> 900IU/L), increased CRP level, and leukocyte count with no signs of cholangitis. [doi.org]

[…] in serum amylase level (4 h) or a 3-fold increase (24 h) above the upper normal limit. [scielo.br]

[…] in the serum amylase level at least three times the normal within 24 hours after ERCP[3] Incidence Pancreatitis is the most common complication associated with ERCP. [wikidoc.org]

Perforated Peptic Ulcer

[…] no it does not ,increased amylase is senitive,but not specific for pancreatitis, increased levels are seen in acute pancreatitis, chronic pancreatitis, pesudocyst, ascitis [usmleforum.com]

trauma, cancer ,biliary diseases, perforated ulcer, chronic liver disease, ectopic pregnancy ,peritonitis ,.In non pancreatic disease, increased amylase does not leads acute [usmleforum.com]

Diabetic Ketotic Coma

Creatine kinase - rhabdomyolysis may also exist (also increased in myocardial infarction). Amylase - if pancreatitis is suspected. Blood cultures. 12-lead ECG. CXR. [patient.info]

Unfortunately, increased serum amylase, which may be released from extrapancreatic tissues, is not definitive for the diagnosis of pancreatitis in DKA. [endocrinologyadvisor.com]

Bulimia Nervosa Purging Type

Although she gradually increased her body weight, she decided to binge-eat and searched for vomiting methods on the internet. [ncbi.nlm.nih.gov]

After five weeks of inpatient treatment, she was discharged at a weight of 35.4 kg with a blood potassium level of 3.8 mEq/L, and a blood amylase level of 95 U/L. [ncbi.nlm.nih.gov]

Acute Intermittent Porphyria

Increases of serum amylase and lipase, as well as mild pancreatic edema on ultrasonography, were noted during the acute attack of AIP, suggesting concomitant acute pancreatitis [ncbi.nlm.nih.gov]

Mesenteric Infarction

Serum amylase was normal. The haemoglobin concentration was stable at this stage. [pmj.bmj.com]

Laboratory tests showed an increased leukocyte count of 12000 /µL with left shift (Neut: 87%). [ispub.com]

Kougias et al., noted that in animal models, D dimer increased within 30 minutes from onset of intestinal ischemia and showed a time dependant increase. [clinicaladvisor.com]

Pancreatic Ductal Stone

Elevated levels—meaning at least a threefold increase—is a sign of pancreatitis. [nyulangone.org]

Blood and Stool Tests Your doctor may draw a small amount of blood to check the levels of the digestive enzymes amylase and lipase. [nyulangone.org]

Pancreatic Adenocarcinoma

Elevated levels should drop with successful treatment; subsequent increases indicate progression. Amylase and lipase levels are usually normal. [msdmanuals.com]

Systemic Lupus Erythematosus

Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology 135, 194–204 (2008). 18. [dx.doi.org]

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of Toll-like receptor 4. J. Exp. Med. 209, 2395–2408 (2012). 17. Lammers, K. M. et al. [dx.doi.org]

Sjögren Syndrome

Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology 135, 194–204 (2008). 18. [dx.doi.org]

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of Toll-like receptor 4. J. Exp. Med. 209, 2395–2408 (2012). 17. Lammers, K. M. et al. [dx.doi.org]

Splenic Rupture

This, in turn, may result in increased morbidity and even mortality. [ispub.com]

Therefore, spontaneous splenic rupture should be considered in the differential diagnosis in any patient presenting with a raised amylase and is haemadynamically unstable. [ispub.com]

Postcholecystectomy Syndrome

This is the increase in the normal amounts of a digestive enzyme, serum amylase. [howshealth.com]

Chronic Alcoholism

Of five chronic alcoholics with acute skeletal muscle necrosis (rhabdomyolysis) three developed acute heart failure with disturbances of rhythm and conduction. Symptoms came on abruptly after a period of intensified drinking. Myocardial infarction, thiamine deficiency, and cobalt intoxication were excluded. Probably[…] [ncbi.nlm.nih.gov]

Chronic Kidney Insufficiency

Abstract Anemia is a major problem in patients with chronic kidney insufficiency. The development of recombinant human erythropoietin has enabled physicians to correct this anemia. Although anemia has not been considered to be a common or important contributor to congestive heart failure, anemia of any cause can[…] [ncbi.nlm.nih.gov]

Small Bowel Obstruction

We describe a case of ischemia complicating acute small-bowel obstruction in which retrospective on-demand spectral analysis using dual-layer spectral detector computed tomography (CT) provided a higher degree of confidence pertaining to the diagnosis. Dual-layer spectral detector CT enables retrospective[…] [ncbi.nlm.nih.gov]

Appendicitis

Appendicitis Definition Appendicitis is an inflammation of the appendix, which is the small, finger-shaped pouch attached to the beginning of the large intestine on the lower-right side of the abdomen. Appendicitis is a medical emergency, and if left untreated, the appendix may rupture and cause a potentially fatal[…] [encyclopedia.com]