Alzheimer Disease
Abstract The brains of Alzheimer's disease sufferers are characterized by amyloid plaques and neurofibrillary tangles.[doi.org]
Zinc has actually been shown to reduce the toxic effect of the amyloid plaques by changing the amyloid proteins into a shape that is less harmful to the brain.[alzheimers.org.uk]
Immunisation of patients with Alzheimer's disease with full-length amyloid-beta peptide (Abeta(42)) can clear amyloid plaques from the brain.[ncbi.nlm.nih.gov]
Amyloidosis
Because of this close link, gradual accumulation of A β into amyloid plaques has been reported in brain areas with intense neuronal activity, including cortical regions that[ncbi.nlm.nih.gov]
We present a 71-year-old man that presented to our department because of exuberant purpuric plaques in the anogenital area as the first manifestation of an amyloid light-chain[ncbi.nlm.nih.gov]
Neuropathological examination during end-stage disease showed the deposition of prion protein in the form of frequent cortical amyloid plaques, cerebral amyloid angiopathy[doi.org]
Secondary Amyloidosis
Seite 451 - Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked[books.google.de]
Nodules/Plaques of amyloid can be seen in the epi/endocardium Micro: Seen in the coronary vessels or surrounding them.[ilovepathology.com]
In the United Kingdom, a nuclear medicine scan using radiolabeled SAP (serum amyloid P component) has been developed; it is not available elsewhere.[clinicaladvisor.com]
Systemic Amyloidosis
Amyloid 13, 20–23 (2006). 60. Burns, M. P. et al. Co-localization of cholesterol, apolipoprotein E and fibrillar Aβ in amyloid plaques. Mol. Brain.[doi.org]
Amyloid cutaneous infiltrative lesions like papules, nodules, or plaques with a serous-hemorrhagic aspect were found in the eyelids, neck and retroauricular region, among[ncbi.nlm.nih.gov]
Amyloid 13, 20–23 (2006). [ PubMed ] [ Google Scholar ] Burns M. P. et al. Co-localization of cholesterol, apolipoprotein E and fibrillar Aβ in amyloid plaques. Mol.[ncbi.nlm.nih.gov]
Amyloidosis in Familial Mediterranean Fever
Amyloid — A waxy translucent substance composed mostly of protein, that forms plaques (abnormal deposits) in the brain.[medical-dictionary.thefreedictionary.com]
Amyloidosis — Accumulation of amyloid deposits in various organs and tissues in the body such that normal functioning of an organ is compromised.[medical-dictionary.thefreedictionary.com]
Creutzfeldt Jakob Disease
[…] in addition to disease duration, in generating white matter PrP-amyloid plaques in p-CJDMM1.[ncbi.nlm.nih.gov]
KEYWORDS: Creutzfeldt-Jakob disease; MV2K C; cerebellum; single unglycosylated band; small amyloid plaques[ncbi.nlm.nih.gov]
Microscopically visible kuru-type amyloid plaques were found in 5% of patients with Creutzfeldt-Jakob disease, 75% of those with kuru, and 100% of those with Gerstmann-Sträussler-Scheinker[ncbi.nlm.nih.gov]
Hepatosplenic Amyloidosis
Harry L. Ioachim, L. Jeffrey Medeiros Lippincott Williams & Wilkins, 2009 - 680 من الصفحات Now in its Fourth Edition, this comprehensive, practical, and thoroughly illustrated reference offers valuable guidance in the diagnostic interpretation of lymph node biopsies. It provides encyclopedic coverage of all the various[…][books.google.com]
Gingivitis
[…] of AD-like plaques, and results in alveolar bone loss compared to control hAPP-J20 mice ( 15 ).[doi.org]
In transgenic mice overexpressing mutated human amyloid precursor protein (hAPP-J20), oral infection with P. gingivalis impairs cognitive function, increases the deposition[doi.org]
Mild Cognitive Impairment
plaque distribution from autopsy studies of Alzheimer's disease.[ncbi.nlm.nih.gov]
Amyloid plaques visible in the brain. Public Health Image Library/Wikimedia Commons.[theconversation.com]
These changes have been observed in autopsies and include abnormal clumps of beta-amyloid plaques and microscopic protein clumps of tau associated with Alzheimer’s disease[belmarrahealth.com]
Periodontitis
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice.[doi.org]
Although there have been hundreds of drug trials in the last 15 years, none have been shown to prevent the stickly amyloid plaques and misfolded proteins which stop brain[telegraph.co.uk]
The senile plaques are primarily composed of β-amyloid (Aβ) peptide, which is a 39–43 amino acidic peptide formed upon proteolytic processing, by β- and γ-secretases (Haass[ncbi.nlm.nih.gov]