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32 Possible Causes for Amyloidosis, Polyclonal Hyperglobulinemia

  • Castleman Disease

    The treatment of amyloidosis secondary to CD remains to be uncertain.[ncbi.nlm.nih.gov] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov] , hypoalbuminemia, polyclonal hypergammaglobulinemia, leukocytosis, thrombocytosis or splenomegaly. 1,4 In contrast to the localized form, the clinical course of the multicentric[scielo.br]

  • Primary Myelofibrosis

    Abnormalities of humoral immunity: variety of autoantibodies and circulating immune complexes may be detected and amyloidosis may develop.[patient.info] Polyclonal hyperglobulinemia may be present. Patients with sporadic idiopathic or familial pulmonary hypertension have significant marrow fibrosis.[patient-help.com] A variety of autoantibodies and circulating immune complexes may be detected, and amyloidosis may develop.[emedicine.medscape.com]

  • Hyperproteinemia

    : A Review JAHA 2012 Key learning points: Patients presenting with multiorgan derangement should be screened for amyloidosis.[imreference.com] (just like hyperprotenemia) (1) hemoconc (2) inflammation (3) B-lymphocyte neoplasia how do you differentiate between inflammatory and neoplastic Hyperglobulinemia?[memorize.com] More serious underlying conditions include: bone marrow problems, immune system disorders like HIV/AIDS, monoclona gammopathy, multiple myeloma, and amyloidosis.[reference.com]

  • Multicentric Castleman's Disease

    hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org] It is quite rare to diagnose interstitial nephritis and secondary amyloidosis during the course of Castleman's disease (CD).[ncbi.nlm.nih.gov] Patients with MCD may reveal raised serum C-reactive protein level, polyclonal hyperglobulinemia, anemia of microcytic hypochromic nature, low albumin level, and high cholesterol[lungindia.com]

  • MALT Lymphoma

    Localized (primary) pulmonary amyloidosis associated with pulmonary low-grade B cell lymphoma is rarely occurred.[ncbi.nlm.nih.gov] Not only MALT lymphoma, but also SjS can cause secondary hyperglobulinemia. Indeed, immunoelectrophoresis-serum test showed a polyclonal pattern of hyperglobulinemia.[ncbi.nlm.nih.gov] Systemic amyloid light chain amyloidosis (AL amyloidosis) is usually seen in association with a plasma cell disorder.[ncbi.nlm.nih.gov]

  • Polyclonal Hypergammaglobulinemia

    NOS ( R77.1 ) monoclonal gammopathy (of undetermined significance) ( D47.2 ) Excludes2 transplant failure and rejection ( T86 .-) D89.0 Polyclonal hypergammaglobulinemia[icd10coded.com] She was diagnosed with AL amyloidosis and treated with bortezomib-based chemotherapy, readily leading to the hematological response fulfilling the criteria of very good partial[jstage.jst.go.jp] Aids in the diagnosis and monitoring of multiple myeloma, lymphocytic neoplasms, Waldenstrom's macroglobulinemia, amyloidosis, light chain deposition disease and connective[pathology.med.umich.edu]

  • Rosai-Dorfman Disease

    DISEASE ASSOCIATIONS CHARACTERIZATION AMYLOIDOSIS Rosai-Dorfman disease and generalized AA amyloidosis: a case report.[thedoctorsdoctor.com] hyperglobulinemia.[ncbi.nlm.nih.gov] The typical clinical features of this disease include bilateral painless lymphadenopathy, fever, and polyclonal hyperglobulinemia.[jdrntruhs.org]

  • IgG4-Related Retroperitoneal Fibrosis

    Other conditions that may simulate RPF include periaortic hematoma and amyloidosis.[emedicine.medscape.com] hyperglobulinemia.[hematologyandoncology.net] […] ureteric obstruction and either acute kidney injury or chronic kidney disease - eg, retroperitoneal abscess, periaortic haematoma, pelvic surgery, radiation therapy and amyloidosis[patient.info]

  • Hyperglobulinemic Purpura

    Other immunologic abnormalities include a polyclonal hyperglobulinemia and positive tests for cryoglobulins; these cryoglobulins may contain monoclonal IgMK proteins.[enotes.tripod.com] […] after trauma: a case report and discussion of the rate of progression to systemic amyloidosis.[doximity.com] NOS (R77.1) monoclonal gammopathy (of undetermined significance) (D47.2) Excludes2: transplant failure and rejection (T86.-) D89.0 Polyclonal hypergammaglobulinemia Benign[en.wikisource.org]

  • Idiopathic Cryoglobulinemia

    (see Amyloidosis, [[Amyloidosis]]): produces both distal RTA and proximal RTA Cryoglobulinemia (see Cryoglobulinemia, [[Cryoglobulinemia]]) Multiple Myeloma (see Multiple[mdnxs.com] NOS ( R77.1 ) monoclonal gammopathy (of undetermined significance) ( D47.2 ) Excludes2 transplant failure and rejection ( T86 .-) D89.0 Polyclonal hypergammaglobulinemia[icd10coded.com] M-protein related Sensory-Motor Axonal Demyelination More commonly IgG or IgA General patterns of neuropathy in myeloma without amyloidosis Onset: Before or after diagnosis[neuromuscular.wustl.edu]

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