Anarthria: Causes & Reasons

Possible Causes for Anarthria

Locked-in syndrome is a state of preserved consciousness in the setting of quadriplegia, anarthria, and usually also includes lateral gaze palsy. [ncbi.nlm.nih.gov]

The characteristics of the syndrome are quadriplegia and anarthria with preservation of consciousness. [bmj.com]

Upper lid and vertical eye movements are usually preserved in patients with the "locked-in" syndrome, a condition manifested by anarthria, spastic quadriparesis, and intact [ncbi.nlm.nih.gov]

Amyotrophic Lateral Sclerosis

AAC use is associated with improved quality of life and mood in people with severe dysarthria/anarthria ( Caligari, Godi, Guglielmetti, Franchignoni, & Nardone, 2013 ; Korner [doi.org]

[…] individual course of the disease, progressive muscle weakness is virtually inevitable in most patients and may finally lead to tetraplegia, chronic respiratory failure, anarthria [dovepress.com]

Traumatic Brain Injury

The immediate effects of traumatic brain injury include cell injury or death, neurovascular disruption, neurotransmitter dysfunction, and biochemical imbalance. The most common neurological finding in traumatic brain injury is loss of consciousness. The Glasgow Coma Scale (GCS) is used to assess consciousness and the[…] [symptoma.com]

Stroke

OBJECTIVE: ed to investigate the association between blood pressure and acute phase stroke lethality in a Brazilian intensive care unit. METHODS: This was an observational, prospective cohort study of hemorrhagic and ischemic stroke intensive care patients. The primary outcome was all-cause mortality during the[…] [ncbi.nlm.nih.gov]

Infantile-Onset Ascending Hereditary Spastic Paralysis

During the first decade of life, the disease progressed to tetraplegia, anarthria, dysphagia, and slow eye movements. [ncbi.nlm.nih.gov]

Thymidine Kinase 2 Deficiency

Dysphagia and speech disturbances are common late-onset manifestations resulting in weight loss and anarthria in severe cases. [ncbi.nlm.nih.gov]

Adult-Onset Dystonia - Parkinsonism

Yoshikuni Mizuno, Abraham Fisher, Israel Hanin Springer Science & Business Media, 31.03.2002 - 566 Seiten 1h The 5 International Conference on the Progress in Alzheimer's Disease and Parkinson's 51 1 Disease took place from March 31 to April 5 \ 2001 in Kroto, Japan. This international 1 conference was organized as a[…] [books.google.de]

Pseudobulbar Palsy

The patient presented with sudden onset of dysphagia, anarthria, and glossplegia. [ncbi.nlm.nih.gov]

Disorders of articulation [ 2 ] This is also called dysarthria or anarthria. [patient.info]

[Case Reports] Ugeskr Laeger. 2022 07 11; 184(28)Zarifkar P, Amiri M, Hansen KUL Sudden onset anarthria and dysphagia without lateralised neurologic symptoms should prompt [unboundmedicine.com]

Foix-Alajouanine Syndrome

Postoperatively, we observed the mouth half open, drooling saliva, inability to move her tongue and anarthria. [content.sciendo.com]

The next day she became acutely altered with anarthria, difficulty speaking, and stiff facial muscles. [academic.oup.com]

[…] examination results were significant for volitional paralysis of his bilateral upper and lower face, including the orbicularis oculi, orbicularis oris, and masseter muscles, anarthria [jamanetwork.com]

Receptive Aphasia

Brain stem stroke may lead to bilateral signs with dysarthria or anarthria. [aacknowledge.org.uk]

Strictly speaking, the words anarthria and aphasia mean a total absence of ability to form speech or language but they are often used when dysarthria and dysphasia would be [aacknowledge.org.uk]

Oligoastrocytoma

Abstract The clinical and histological characteristics of oligodendroglioma and oligoastrocytoma were investigated in patients, mainly adults with supratentorial tumors, who were treated with surgery and radiotherapy, and with chemotherapy for recurrent, anaplastic tumors, or both. The median survival time was 13.2[…] [ncbi.nlm.nih.gov]

Foix-Chavany-Marie Syndrome

Abstract Anarthria and bilateral central facio-linguovelo-pharyngeo-masticatory paralysis with "automatic voluntary dissociation" are the clinical hallmarks of Foix-Chavany-Marie [ncbi.nlm.nih.gov]

Over the hospital stay, the patient’s motor function improved but her anarthria persisted. [journals.iupui.edu]

The patient’s symptoms included anarthria, weakness of bilateral masseters, and lateral/medial pterygoids without dysphagia. [journals.iupui.edu]

Hypokinetic Dysarthria

Broussolle E., Bakchine S., Tommasi M., Laurent B., Bazin B., Cinotti L. et al., 1996, Slowly progressive anarthria with late anterior opercular syndrome: A variant form of [siba-ese.unisalento.it]

Juvenile GM2-Gangliosidosis

The mean age of onset of speech problems was 7.0 ± 5.6 years, with a mean time of progression to anarthria of 5.6 ± 5.3 years. [ncbi.nlm.nih.gov]

The mean time progression from mild dysarthria to anarthria was 5.6 ± 5.3 years (range: 1–14 years). Speech deterioration in jGM2. Shown are the means ± SDs. [ncbi.nlm.nih.gov]

The mean interval from the progression of mild dysarthria to severe dysarthria was 2.4 years (range: 0.5–7.0 years) and from severe dysarthria to anarthria was 3.2 years [ncbi.nlm.nih.gov]

Aicardi-Goutières Syndrome Type 3

Patient 1 was an 18‐year‐old female with spastic quadriplegia and anarthria. [onlinelibrary.wiley.com]

Manifestations included spastic quadriplegia and anarthria but preserved intellect and increased iron signal in the basal ganglia. [onlinelibrary.wiley.com]

Both had spastic quadriplegia, anarthria, preserved cognitive function, absent leukoencephalopathy or brain calcifications but evidence of excess iron accumulation in the [onlinelibrary.wiley.com]

Complete Locked-in Syndrome

[…] muscles Paralysis of all 4 limbs and torso ( quadriplegia ) → spasticity, ↑ deep tendon reflexes, positive bilateral Babinski's sign Bulbar palsy : inability to speak ; ( anarthria [amboss.com]

The symptoms are tetraplegia, double-sided facial paresis, anarthria/dysarthrophonia, dysphagia and reactive involuntary laughing and crying. [naric.com]

Progressive Bulbar Paralysis

[…] elderly women seem to be the predominant group of patients that suffer from progressive bulbar palsy and usually the first manifestation is progressive dysarthria (or even anarthria [symptoma.com]

Gangliosidosis

Dysarthria/anarthria (97%) is frequent, and eye movements are normal. Bone marrow examination may show Gaucher‐like foam cells (39%). [onlinelibrary.wiley.com]

He developed dystonic posturing of both lower limbs by 13 years of age, which progressed to anarthria, blepharospasm, cervical, and truncal dystonia by the age of 16 years [neurologyindia.com]

Her subsequent clinical course over the years is characterized by progressive spastic-dystonic tetraparesis with anarthria with marked oromotor dystonia. [movementdisorders.org]

ATP1A3-Related Neurologic Disorders

A previously healthy child presented at 20 months with transient afebrile episodes accompanied by abnormal ocular movement, anarthria, generalized hypotonia, paresis-dystonia [frontiersin.org]

Aicardi-Goutières Syndrome Type 2

Manifestations included spastic quadriplegia and anarthria but preserved intellect and increased iron signal in the basal ganglia. [onlinelibrary.wiley.com]

[…] describe two siblings (sister and brother) diagnosed with AGS2 in their second decade, who exhibited static encephalopathy since 1 year of age with spastic quadriplegia and anarthria [onlinelibrary.wiley.com]

PLA2G6-Associated Neurodegeneration

Three years after the onset of motor symptoms, he was confined to a wheelchair with anarthria, and he was totally dependent on assistance from others in daily living activities [bmcneurol.biomedcentral.com]

Neurodegeneration with Brain Iron Accumulation

From our series of patients one patient with PKAN and a progressive severe dystonic syndrome, cerebellar ataxia, retinitis pigmentosa and eventual anarthria had a novel combination [ncbi.nlm.nih.gov]

Kufor-Rakeb syndrome (KRS) • Caused by mutations in the ATP13A2 gene • Parkinsonism, anarthria, spastic paraparesis, and pyramidal tract signs • Facial-faucial finger mini-myoclonus [slideshare.net]

Clinical features of KRS include prominent parkinsonism (hypomimia, rigidity, festination, and bradykinesia), anarthria, spastic paraparesis, and pyramidal tract signs. [ajnr.org]

Kufor-Rakeb Syndrome

[…] behavior Psychotic episodes Dementia Hallucinations Seizures Spasticity Parkinsonism Myoclonus Hyperreflexia Rigidity Postural instability Akinesia Hypokinesia Paraparesis Anarthria [familydiagnosis.com]

[…] facies; [Eyes]; Supranuclear gaze palsy; Oculogyric dystonic spasms NEUROLOGIC: [Central nervous system]; Parkinsonism; Hypokinesia; Akinesia; Mask-like facies; Rigidity; Anarthria [genome.jp]

[…] rigidity 0002063 Slow saccadic eye movements Slow eye movements 0000514 30%-79% of people have these symptoms Abnormality of finger Abnormalities of the fingers 0001167 Anarthria [rarediseases.info.nih.gov]

Rolandic Epilepsy

During seizures, patients are unable to control their mimic musculature and may suffer from anarthria. [symptoma.com]

Sialorrhea (excessive saliva flow) and anarthria (a loss of control of the muscles that control speech, resulting in the inability to utter words) are common. [epilepsyqueensland.com.au]

Arrest of speech is a form of anarthria. The child is unable to utter a single intelligible word and attempts to communicate with gestures. [en.wikipedia.org]

Secondary Parkinsonism

This is a case report of a 53 year old right handed man with progressive anarthria and secondary Parkinsonism over a period of six years. [ncbi.nlm.nih.gov]

Spastic Quadriplegic Cerebral Palsy Type 2

The disease progressed to tetraplegia, anarthria, dysphagia, and slow eye movements in the second decade. [neurology.org]

During the first decade of life, the disease progresses to tetraplegia, anarthria, dysphagia, and slow eye movements. [cmm.ucsd.edu]

GM2 Gangliosidosis

The mean age of onset of speech problems was 7.0 +/- 5.6 years, with a mean time of progression to anarthria of 5.6 +/- 5.3 years. [ncbi.nlm.nih.gov]

He developed dystonic posturing of both lower limbs by 13 years of age, which progressed to anarthria, blepharospasm, cervical, and truncal dystonia by the age of 16 years [neurologyindia.com]

Her subsequent clinical course over the years is characterized by progressive spastic-dystonic tetraparesis with anarthria with marked oromotor dystonia. [movementdisorders.org]

Vertebral Artery Thrombosis

[…] vertebrobasilar artery (VBA) territory is affected, the most likely cause is occlusion of the basilar artery, which may, in turn, promote ischemia of the pons, quadriplegia, and anarthria [symptoma.com]

Basilar Artery Thrombosis

Diagnosis of LIS hinges on the clinical prerequisites of quadriplegia or quadriparesis and the inability to speak (anarthria) with preservation of consciousness and eye movements [intjem.springeropen.com]

Ischemic damage to the pontine pyramidal tracts creates the devastating locked-in syndrome characterized by quadriplegia, anarthria, and preserved consciousness. 1 Extended [stroke.ahajournals.org]

This can cause pontine damage resulting in “Locked-In Syndrome” (quadriplegia, anarthria, preserved consciousness). 13, 15 Distal basilar artery occlusion is most commonly [westjem.com]

Despite progression to anarthria, autopsy studies show that anarthria can occur in the absence of significant involvement of the hypoglossal nucleus. [emedicine.medscape.com]

[…] parkinsonism and ALS with dementia of the Alzheimer type.65,66 Atypical presentations were reported, such as bvFTD with chorea and supranuclear gaze palsy, and progressive anarthria [text-br.123dok.com]

Dynamic, spontaneous speech output progressively declines, resulting in anarthria and mutism. A subset of patients presents with rapidly progressive aphasia. [emedicine.medscape.com]