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90 Possible Causes for Anemia, Bicytopenia, Hepatosplenomegaly

  • Gaucher Disease

    We report here the case of a young woman with hepatosplenomegaly, leukopenia, and thrombocytopenia.[ncbi.nlm.nih.gov] A patient known for hepatosplenomegaly with hyperferritinemia, anemia, and thrombocytopenia was admitted for Lewy body dementia and bullous pemphigoid.[ncbi.nlm.nih.gov] Abstract A 38-year-old female patient was diagnosed with anemia for 3 years.[ncbi.nlm.nih.gov]

  • Pancytopenia

    We present case of two Syrian refugee infants with severe vitamin B12 deficiency with pancytopenia, hepatosplenomegaly and leukoerythroblastosis.[ncbi.nlm.nih.gov] […] of bicytopenia and pancytopenia.[ijpmonline.org] Pancytopenia is most commonly seen in aplastic anemia. In aplastic anemia, our immune system attacks the healthy cells of bone marrow.[differencebetween.net]

  • Castleman Disease

    For multicentric disease: multi-region CT bilateral hilar and mediastinal lymphadenopathy centrilobular nodules diffuse abdominal lymphadenopathy hepatosplenomegaly ascites[radiopaedia.org] Investigations showed bicytopenia, nephrotic range proteinuria with hypoalbuminemia, hypogammaglobulinemia, and features of hyaline-vascular type Castleman disease in a lymph[ncbi.nlm.nih.gov] Laboratory findings were consistent with anemia of inflammation. Direct antiglobulin test was positive without any other evidence of autoimmune anemia.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Most of them had anemia, fever, and hepatosplenomegaly on admission.[ncbi.nlm.nih.gov] Patients with primary myelofibrosis may have pancytopenia or bicytopenia and in that respect mimic patients with oligoblastic leukemia (myelodysplasia [MDS]; see Chap. 88)[patient-help.com]

  • Mantle Cell Lymphoma

    Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement.[icd9data.com] Further investigation revealed bicytopenia with splenomegaly and elevated serum creatinine.[ncbi.nlm.nih.gov] A 79-year-old woman with a 3-month history of bruising and heavy menorrhagia presented with ongoing vaginal bleeding, symptomatic anemia, and a right thigh hematoma.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    Physical examination showed jaundice, hepatosplenomegaly, and peripheral facial nerve palsy in addition to dermal nodules.[ncbi.nlm.nih.gov] A 43-year-old female presented with leukocytosis and bicytopenia.[ncbi.nlm.nih.gov] Classic features of ALL include neutropenia, anemia and thrombocytopenia.[symptoma.com]

  • Acute Myelocytic Leukemia

    In all three patients, radionuclide imaging with technetium-99m sulfur colloid showed hepatosplenomegaly, decreased liver uptake, and increased splenic activity.[ncbi.nlm.nih.gov] However, it is not clear whether this autoantibody in AML patients induces frank hemolysis (autoimmune hemolytic anemia, AIHA), as seen in lymphoid neoplasms.[ncbi.nlm.nih.gov] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[bloodjournal.hematologylibrary.org]

  • Autoimmune Hemolytic Anemia

    A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Cold antibody hemolytic anemia is common among the elderly, while warm antibody hemolytic anemia affects all age groups.[symptoma.com] Autoimmune bicytopenia in pulmonary tuberculosis. Report of a pediatric case. Respir Med CME 2008;1:281-3. 9. Safe IP, O'brien C, Ferreira FR, Souza ML, Ramasawmy R.[jahjournal.org]

  • Follicular Lymphoma

    Splenomegaly is present in approximately 50% of patients at presentation, and hepatosplenomegaly may occur.[emedicine.com] In addition, the presence of an autoimmune bicytopenia and a Klinefelter syndrome complicated the clinical context of the patient.[ncbi.nlm.nih.gov] We report a 65-year old patient with autoimmune hemolytic anemia (AIHA) complicated by a follicular lymphoma (FL) in situ and other B-cell clones in the spleen.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Due to presenting complaint of bleeding diathesis and absence of hepatosplenomegaly, the case was undiagnosed for CML until the patient reported to us.[ncbi.nlm.nih.gov] In contrast to patients with RA and only dyserythropoiesis, patients with multilineage dysplasia have bicytopenia or pancytopenia, a higher incidence of cytogenetic abnormalities[doi.org] We report a case of a chronic myeloid leukemia patient showing progressive bone marrow fibrosis and anemia during imatinib therapy.[ncbi.nlm.nih.gov]

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