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595 Possible Causes for Anemia, Dyspnea, Erythrocytosis

  • Paraneoplastic Syndrome

    Three types of paraneoplastic anemias may be described, as follows: Chronic anemia resulting from an anti-erythropoietin factor, reduction in mean red blood cell (RBC) life[emedicine.medscape.com] Review of systems was significant for hemoptysis, dyspnea on exertion and dull achy left anterior chest and shoulder pain.[healio.com] Erythrocytosis is common in cancers of the liver, kidney, adrenal glands, lung, thymus, and CNS as well as in gynecologic tumors and myosarcomas.[emedicine.medscape.com]

  • Myeloproliferative Disease

    Abstract Here is reported the case of an elderly woman that, after surgical intervention, showed an important anemia, leucocytosis and thrombocytopenia.[ncbi.nlm.nih.gov] .  35 y/o previously healthy man  9 month history of tachycardia and dyspnea on exertion  Dec. 2011, dyspnea becomes more severe  Hospitalized in Miami when found to have[slideshare.net] These data suggest that erythrocytosis and granulocytosis in JAK2(V617F) mice are the net result of a complex interplay between cell intrinsic and extrinsic factors.[ncbi.nlm.nih.gov]

  • Post-Polycythemia Vera Myelofibrosis

    Myelofibrosis patients with ASXL1 lesions were more likely to have received anemia-directed therapy compared to those without lesions [15/26 (58%) versus 11/39 (23%); P 0.02[ncbi.nlm.nih.gov] Grade 3 AEs included anemia (n 3), neutrophil decrease (n 2), amylase increase (n 2), lipase increase (n 2), diarrhea (n 2), colitis (n 1), dyspnea (n 1), pneumonia (n 1),[hematologytimes.com] We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man[ncbi.nlm.nih.gov]

  • Thalassemia

    We identified two causes of hemolytic anemia (congenital erythropoietic porphyria and alpha thalassemia) in this patient.[ncbi.nlm.nih.gov] He presented with chest discomfort and progressive dyspnea. Early echocardiogram showed mild pericardial effusion.[ncbi.nlm.nih.gov] Following extensive cardiological and neurological investigation, it was felt that significant erythrocytosis was the most likely cause.[ncbi.nlm.nih.gov]

  • Eisenmenger Syndrome

    The patients usually present with cyanosis, erythrocytosis, clubbing of fingers, syncope, arrhythmias, bleeding disorders and anemia.[symptoma.com] […] elevated in ES patients and fell significantly with sildenafil therapy that was associated with improved exercise tolerance, implying thereby a role of J receptors in producing dyspnea[ncbi.nlm.nih.gov] When bunazosin was stopped, the erythrocytosis increased, but when it was resumed, the erythrocytosis and general fatigue diminished.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[ncbi.nlm.nih.gov] Dyspnea, tachycardia and dizziness are experienced in case of severe anemia.[symptoma.com] The laboratory findings showed leuko-and erythrocytosis, increased levels of urea-BUN (32 mmol/l) and creatinine (766 mmol/l) as well as uric acid (920 mmol/l).[ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    , may have basophils, platelets Anemia, leukocytosis, or nl platelets platelets, often abnormal Dimorphic RBC, platelets Macrocytic anemia, or nl platelets Marrow Myeloids[surgpathcriteria.stanford.edu] A 52-year-old African American male with ET presented with chest pain, shortness of breath, and dyspnea on exertion.[ncbi.nlm.nih.gov] […] at diagnosis and for patients who subsequently develop thrombocytosis, leukocytosis, or erythrocytosis during follow-up, even for CML patients in complete cytogenetic response[ncbi.nlm.nih.gov]

  • High Output Heart Failure

    Anemia causes cutaneous pallor and fatigability which overlaps with that induced by the heart failure, peripheral vasodilatation caused by vascular nitric oxide synthase and[symptoma.com] After the procedure, dyspnea was improved and procedure related complication was not seen.[ncbi.nlm.nih.gov] VEGF, also increases the EPO concentrations in a dose-dependent manner. 71 Likewise, transgenic mice carrying both human renin and human angiotensinogen have persistent erythrocytosis[revespcardiol.org]

  • Methemoglobinemia

    RESULTS: Six cases of methemoglobinemia, one case of methemoglobinemia, with concomitant hemolytic anemia, and one case of hemolytic anemia were identified.[ncbi.nlm.nih.gov] Methemoglobinemia can cause life-threatening hypoxia associated with cyanosis and dyspnea not responsive to oxygen.[ncbi.nlm.nih.gov] erythrocytosis.[nature.com]

  • Autoimmune Hemolytic Anemia

    Autoimmune haemolytic anaemia Autoimmune hemolytic anemia NOS (disorder) Autoimmune hemolytic anemia ANEMIA, AUTOIMMUNE HEMOLYTIC AIHA AHA edit English autoimmune hemolytic[wikidata.org] The patient suddenly developed hematuria and dyspnea on exertion while receiving adalimumab treatment.[ncbi.nlm.nih.gov] While hemolysis can be a lifelong asymptomatic condition, it most often presents as anemia when erythrocytosis cannot match the pace of red cell destruction.[aafp.org]

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