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2,092 Possible Causes for Anemia, Hepatomegaly, Jaundice

  • Infectious Mononucleosis

    We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement.[ncbi.nlm.nih.gov] The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults.[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    […] spread to other parts of the body then the following symptoms may be experienced by the individual: Low back pain or pain in the pelvis to bone metastasis Abdominal pain and jaundice[epainassist.com] An anemia-inducing substance (AIS) was found as a protein, with a molecular weight of 50,000 on SDS electrophoresis gel, that decreased the osmotic resistance of erythrocytes[ncbi.nlm.nih.gov] Laboratory findings showed no abnormalities, except for a slightly elevated C-reactive protein value and iron deficiency anemia.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Although the severe obstructive jaundice requiring endoscopic therapy following cholecystectomy was complicated, critical intravascular hemolysis and thrombosis were not observed[ncbi.nlm.nih.gov] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com] Anemia work-up revealed a misunderstood association of a hemolytic anemia with a negative direct antiglobulin test and iron deficiency.[ncbi.nlm.nih.gov]

  • Congenital Toxoplasmosis

    Because biliary atresia can coexist with either congenital infection or inborn errors of metabolism, evaluation for an obstructive etiology of jaundice in infants with a recognized[ncbi.nlm.nih.gov] During the first month of life, physical examination was normal in 34.5%, and for those with clinical signs and symptoms, the main manifestations were hepatomegaly and/or[ncbi.nlm.nih.gov] […] ascites with persistent anemia during the first week of life.[ncbi.nlm.nih.gov]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] The presence of hepatomegaly was a statistically significant predictor for poor physical QOL (OR   8.5, p   0.02).[ncbi.nlm.nih.gov] Beta-thalassemia and sickle cell anemia are two of the most common diseases related to the hemoglobin protein.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[hopkinsmedicine.org] Additional autopsy findings included cardiomegaly with a heart weight of 450 gm (312 78), right atrial and right ventricular chamber dilatation, and hepatomegaly with a liver[ncbi.nlm.nih.gov] Sickle cell anemia is an autosomal recessive disorder.[themedicalbiochemistrypage.org]

  • Malaria

    A 5-year-old immunocompetent girl presented with fever, jaundice, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] Patients with heavy hepatocyte load may present with hepatomegaly.[symptoma.com] AL treatment of severe malaria can cause delayed hemolytic anemia.[ncbi.nlm.nih.gov]

  • Alpha Thalassemia

    Hereditary spherocytosis (HS) is a common inherited hemolytic anemia characterized by heterogeneous clinical presentations with variable degrees of anemia, jaundice, splenomegaly[ncbi.nlm.nih.gov] Concurrent alpha thalassemia might be a protective trait against significant hepatomegaly in sickle cell anaemia patients more than 60 months of age at Mulago hospital.[ncbi.nlm.nih.gov] Two hundred six patients with hypochromic microcytic anemia were evaluated for alpha thalassemia.[ncbi.nlm.nih.gov]

  • Fetal Erythroblastosis

    This can indicate why a baby may appear jaundiced or anemic.[prezi.com] Also, the newborn will be anemic and pale and present splenomegaly and hepatomegaly, caused by extramedullary hematopoiesis. Portal hypertension has the same cause.[symptoma.com] Ultrasonography may reveal hepatomegaly, abdominal enlargement, ascites, or signs of hydrops fetalis.[quizlet.com]

  • Pernicious Anemia

    Jaundice: There is mild jaundice caused by the excessive breakdown of hemoglobin due to ineffective erythropoiesis in the bone marrow.[symptoma.com] Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Hepatomegaly and splenomegaly may be present.[patient.info]

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