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393 Possible Causes for Anemia, Hepatomegaly, Leg Edema

  • Liver Cirrhosis

    Cardinal symptoms include fasting hypoglycemia, lactic acidosis and hepatomegaly as well as neutropenia.[ncbi.nlm.nih.gov] Glycated hemoglobin (HbA1c) is a widely used marker of glycemic control but can be affected by hemolytic anemia.[ncbi.nlm.nih.gov] A 65-year-old male with liver cirrhosis of alcoholic etiology was admitted to hospital with bilateral leg edema, ascites, and marked weakness.[ncbi.nlm.nih.gov]

  • Castleman Disease

    Examination revealed pallor; generalized edema; axillary, cervical, and inguinal lymphadenopathy; hypertension; and hepatomegaly.[ncbi.nlm.nih.gov] Laboratory findings were consistent with anemia of inflammation. Direct antiglobulin test was positive without any other evidence of autoimmune anemia.[ncbi.nlm.nih.gov] […] swelling (edema) Skin rashes The symptoms of MCD usually come on gradually.[sylvant.com]

  • Amyloidosis

    Hepatic involvement is common, but the clinical manifestations are usually mild with hepatomegaly and an elevated alkaline phosphatase level.[ncbi.nlm.nih.gov] CASE REPORT We present a case of gelsolin amyloidosis in a male of African descent with an atypical clinical presentation including fevers, skin rash, polyneuropathy, and anemia[ncbi.nlm.nih.gov] This may result in a condition called nephrotic syndrome, where there is excess protein in the urine and the lower legs can become swollen (also called “edema”).[amyloidosis.org]

  • Hereditary ATTR Amyloidosis

    Common physical findings in advanced disease include the following: Cachexia Peripheral edema Hepatomegaly Purpura Orthostatic hypotension Impaired sensation and/or strength[emedicine.medscape.com] Microalbuminuria, heavy proteinuria and progressive renal failure that leads to insufficiency is seen in patients with kidney deposits, but also anemia, since EPO production[symptoma.com] Support stockings may be recommended for patients with leg edema (swelling).[ttrstudy.com]

  • ALK+ Histiocytosis

    Hepatomegaly manifests in upper abdominal distension, tenderness or pain, loss of appetite, and the formation of edema.[symptoma.com] Fever, splenomegaly and hepatomegaly are the most common early findings; b. Lymph node enlargement, skin rash, and neurologic abnormali ties may also occur.[hopkinsmedicine.org] When infants present with anemia, thrombocytopenia, and hepatosplenomegaly, this entity should be included in the differential diagnosis along with hemophagocytic lymphohistiocytosis[ncbi.nlm.nih.gov]

  • Congestive Heart Failure

    Right upper quadrant sonogram revealed hepatomegaly of 15 cm, trace amount of perihepatic ascites, pericholecystic fluid, and also thickened edematous gallbladder wall with[ncbi.nlm.nih.gov] Anemia management has been demonstrated to be cost-effective.[ncbi.nlm.nih.gov] Complications include swelling of the legs (edema), kidney problems and fluid in the lungs.[hopkinsmedicine.org]

  • Heart Failure

    A physical examination revealed a systolic murmur, which was best audible in the right parasternal side, ascites, and hepatomegaly.[ncbi.nlm.nih.gov] After providing supportive treatment, the heart failure symptoms disappeared and her anemia had improved.[ncbi.nlm.nih.gov] The weakening of the heart's pumping ability causes Blood and fluid to back up into the lungs The buildup of fluid in the feet, ankles and legs - called edema Tiredness and[medlineplus.gov]

  • Systemic Amyloidosis

    Examination and tests in this patient also revealed anemia, hepatomegaly, infiltrative cardiomyopathy, polyneuropathy and immunoglobulin l deposition, favoring a diagnosis[ncbi.nlm.nih.gov] During this observation period, the level of IgE gradually increased and, at 2 years after the initial diagnosis, bilateral leg edema and ascites with marked hepatosplenomegaly[ncbi.nlm.nih.gov] Key words: AL Amyloidosis, Proteinuria, Hepatomegaly Advertisement Journal of Contemporary Medical Education SUBMIT YOUR ARTICLE NOW[scopemed.org]

  • Hepatitis

    Findings include: hepatomegaly 15.5 cm at the midclavicular line 4 possible decreased attenuation around the portal system and at the hepatic hilum (periportal edema) possible[radiopaedia.org] RATIONALE: We report a complicated case of cholestatic hepatitis with suspected autoimmune hemolytic anemia (AIHA) and copper toxicity syndrome after HSCT and donor lymphocyte[ncbi.nlm.nih.gov] (called "edema") Bruising or bleeding easily Vomiting of blood or black material; passage of black, tarry stools Changes in mental status and sleep disturbances What causes[hepfi.org]

  • Chronic Lymphocytic Leukemia

    […] of the left zygomatic region; anterior nasal bleeding; pustulous non-itching lesions at the cervical region and posterior thorax; enlarged bilateral axillary lymph nodes; hepatomegaly[ncbi.nlm.nih.gov] Approximately 5-10% of CLL is complicated by autoimmune cytopenia (AIC), such as autoimmune hemolytic anemia (AIHA).[ncbi.nlm.nih.gov] My giant belly was mostly a collection of tumorous lymph nodes that had fused together into larger tumorous masses, and this led to edema in the legs, feet, and, ahem, scrotum[clldiary.blogspot.com]

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