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2,176 Possible Causes for Anemia, Hepatomegaly, Thrombocytopenia

  • Infectious Mononucleosis

    A 49-year-old man with diabetic mellitus suffered from IM with fever, pharyngitis, parotiditis with lymphadenopathies, thrombocytopenia and splenomegaly.[ncbi.nlm.nih.gov] The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] […] characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor, icterus or bronzing of the skin, a moderate degree of splenomegaly, and sometimes hepatomegaly[medical-dictionary.thefreedictionary.com] Anemia work-up revealed a misunderstood association of a hemolytic anemia with a negative direct antiglobulin test and iron deficiency.[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    A rapidly progressive anemia and thrombocytopenia dictated a splenectomy.[ncbi.nlm.nih.gov] However, loss of appetite due to hepatomegaly is not the only condition that causes ASM patients to lose weight: Mast cells also infiltrate the intestinal walls, which causes[symptoma.com] A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing cholangitis[ncbi.nlm.nih.gov]

  • Congenital Toxoplasmosis

    The immediate cause of death was cardiorespiratory failure with antecedent cause of liver failure, renal insufficiency with thrombocytopenia.[ncbi.nlm.nih.gov] During the first month of life, physical examination was normal in 34.5%, and for those with clinical signs and symptoms, the main manifestations were hepatomegaly and/or[ncbi.nlm.nih.gov] […] ascites with persistent anemia during the first week of life.[ncbi.nlm.nih.gov]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] In case of hepatomegaly, the liver extends to more than 3 cm below the right costal margin of the newborn.[symptoma.com] Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Malaria

    […] describ the case of a young soldier who, after returning from Central Africa, presented a fever associated with petechial purpura and gingivorrhagia, hemogram showed deep thrombocytopenia[ncbi.nlm.nih.gov] Patients with heavy hepatocyte load may present with hepatomegaly.[symptoma.com] AL treatment of severe malaria can cause delayed hemolytic anemia.[ncbi.nlm.nih.gov]

  • Gaucher Disease

    Medical examination showed slight splenomegaly (250 62 mm), thrombocytopenia (platelets 51 109/L), anemia (Hb levels 107 g/L), and β-glucocerebrosidase activity (GBA) in leukocytes[ncbi.nlm.nih.gov] After 4years of ERT, therapeutic goals for thrombocytopenia and splenomegaly had been achieved in 100% of patients; goals for anemia and hepatomegaly had been achieved in[ncbi.nlm.nih.gov] Gaucher disease is a common inborn error of metabolism leading to widespread chronic inflammation and often thrombocytopenia.[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    This is the second description of pernicious anemia associated with autoimmune thrombocytopenia.[ncbi.nlm.nih.gov] Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Pernicious anemia (Biermer's anemia, Addison's anemia) is a type of megaloblastic anemia, due to an inability to absorb vitamin B12 (cobalamin).[symptoma.com]

  • Chronic Lymphocytic Leukemia

    There is no or little evidence of anemia or thrombocytopenia.[symptoma.com] […] of the left zygomatic region; anterior nasal bleeding; pustulous non-itching lesions at the cervical region and posterior thorax; enlarged bilateral axillary lymph nodes; hepatomegaly[ncbi.nlm.nih.gov] Approximately 5-10% of CLL is complicated by autoimmune cytopenia (AIC), such as autoimmune hemolytic anemia (AIHA).[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    We are reporting a 4-year-old child who was received for investigation for persistent anemia, prolonged fever, and thrombocytopenia.[ncbi.nlm.nih.gov] Hepatomegaly and liver dysfunction may be found in 20% of patients.[symptoma.com] Here, we describe a patient with HCL who initially presented with pancytopenia and received a diagnosis of aplastic anemia.[ncbi.nlm.nih.gov]

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