Create issue ticket

813 Possible Causes for Anemia, Hepatosplenomegaly, Leukopenia, Monocytosis

  • Infectious Mononucleosis

    Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[ncbi.nlm.nih.gov] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] Abstract Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults.[ncbi.nlm.nih.gov] […] by EBV and of which monocytosis is a finding.[en.wikipedia.org]

  • Chronic Myelomonocytic Leukemia

    Affected individuals present with monocytosis, cytopenias, and extramedullary manifestations like lymphadenopathy and hepatosplenomegaly.[symptoma.com] Not having enough normal white blood cells (leukopenia) can lead to frequent or severe infections .[cancer.org] Abstract Here is reported the case of an elderly woman that, after surgical intervention, showed an important anemia, leucocytosis and thrombocytopenia.[ncbi.nlm.nih.gov] The diagnosis of CMML requires absolute monocytosis ( 1000/μL) in addition to other criteria outlined by the World Health Organization (WHO) classification.(1) Monocytosis[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    Abdominal discomfort is a common symptom, resulting from hepatosplenomegaly.[orpha.net] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[ncbi.nlm.nih.gov] Here, we describe a patient with HCL who initially presented with pancytopenia and received a diagnosis of aplastic anemia.[ncbi.nlm.nih.gov] […] neoplastic hematopoietic disorders, such as lymphoma, myelodysplastic syndromes, multiple myeloma, aplastic anemia, severe megaloblastic anemia, severe lymphocytosis, severe monocytosis[ncbi.nlm.nih.gov]

  • Gaucher Disease

    Abstract The hematologist is at the forefront of specialists to whom patients with Gaucher disease present because of cytopenia and hepatosplenomegaly.[ncbi.nlm.nih.gov] Spleen enlargement and bone marrow replacement cause anemia, thrombocytopenia, and leukopenia.[en.wikipedia.org] Type 1 Gaucher disease (GD1) is characterized by thrombocytopenia, anemia, an enlarged spleen, and liver as well as bone complications (Erlenmeyer flask deformity, osteoporosis[ncbi.nlm.nih.gov] The phenotype was unusually severe with congenital ichthyosis, hepatosplenomegaly, muscular hypotonia, myoclonus and respiratory failure.[ncbi.nlm.nih.gov]

  • Aggressive Systemic Mastocytosis

    The patient was a 37-week-old male, born by caesarean section owing to hepatosplenomegaly and ascites diagnosed in utero, who exhibited extensive cutaneous and systemic manifestations[ncbi.nlm.nih.gov] In fact, bone marrow failure is associated with cytopenias and patients suffering from anemia, leukopenia, or thrombocytopenia may present with pallor, weakness, and fatigue[symptoma.com] Abstract A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing[ncbi.nlm.nih.gov] Respective clinical findings (so called C-Findings) include cytopenias, osteolysis (or osteoporosis) with pathologic fractures, hepatosplenomegaly with impaired liver function[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    Hepatosplenomegaly and laboratory evidence of mild to moderate hepatic dysfunction are the predominant features, with increased aminotransferases and alkaline phosphatase[doi.org] Fever, nausea, vomiting, abdominal pain, leukopenia, thrombocytopenia, coagulopathy, and a marked rise in serum transaminase levels are invariably present.[ncbi.nlm.nih.gov] Ribavirin side effects may be more prominent, and include anemia, skin problems, or breathing problems. Difficulties with sleeping may also be seen with ribavirin.[patients.gi.org] […] autopsy due to nonspecific clinical features Better survival in children than adults ( J Hepatol 2011;55:1222 ) Laboratory Sudden, marked elevation of ALT or AST, fever, leukopenia[pathologyoutlines.com]

  • Systemic Lupus Erythematosus

    Drugs causing leukopenia Some drugs may lead to leukopenia.[news-medical.net] Anemia is a common finding in children with systemic lupus erythematosus (SLE).[ncbi.nlm.nih.gov] She was diagnosed with SLE with pernicious anemia and iron deficiency anemia. The rare association of SLE with pernicious anemia was reported previously in few patients.[ncbi.nlm.nih.gov] A persistent positive antinuclear factor of either speckled or homogeneous pattern with a titer greater than 1:50, leukopenia, thrombocytopenia, or a false-positive Wassermann[doi.org]

  • Rocky Mountain Spotted Fever

    Some individuals with RMSF may also develop abnormal enlargement of the liver and/or spleen (hepatosplenomegaly).[rarediseases.org] Leukopenia, thrombocytopenia, elevated hepatic transaminase levels, and mild anemia are characteristic laboratory findings in anaplasmosis.[doi.org] Laboratory evaluation may demonstrate hyponatremia, anemia, thrombocytopenia, abnormal liver enzymes, and elevated coagulation tests.[ncbi.nlm.nih.gov] Oral formulations of chloramphenicol are not available in the United States, and use of this drug carries the potential for other adverse risks, such as aplastic anemia and[cdc.gov]

  • Acute Myelocytic Leukemia

    In all three patients, radionuclide imaging with technetium-99m sulfur colloid showed hepatosplenomegaly, decreased liver uptake, and increased splenic activity.[ncbi.nlm.nih.gov] The consolidation treatment was the same in both arms but caused significantly more leukopenia and thrombocytopenia in patients previously treated with HIDAC-3-7 induction[ncbi.nlm.nih.gov] However, it is not clear whether this autoantibody in AML patients induces frank hemolysis (autoimmune hemolytic anemia, AIHA), as seen in lymphoid neoplasms.[ncbi.nlm.nih.gov] Symptoms include splenomegaly, monocytosis with granulocytosis, and thrombocytopenia. leukemia cu tis leukemia with leukocytic invasion of the skin marked by pink, reddish[medical-dictionary.thefreedictionary.com]

  • Leukemia

    An additional eight features were present in a third to a half of children: recurrent infections (49%), fatigue (46%), limb pain (43%), hepatosplenomegaly (42%), bruising[ncbi.nlm.nih.gov] Common side effects of Besponsa include low levels of platelets (thrombocytopenia), low levels of certain white blood cells (neutropenia, leukopenia), infection, low levels[fda.gov] ( 3 ) with or without lymphadenopathy, hepatomegaly, splenomegaly, or anemia.[web.archive.org] No other obvious cause for Leukocytosis (e.g. infection, Corticosteroid s) Step 1: Consider secondary causes based on white cell count differential Monocyte predominance (monocytosis[fpnotebook.com]

Similar symptoms