Create issue ticket

1,130 Possible Causes for Anemia, Hepatosplenomegaly, Leukopenia, Monocytosis

  • Infectious Mononucleosis

    Both cases involved young adults presenting with fever, pharyngitis, lymphadenopathy, hepatosplenomegaly, and atypical lymphocytosis confirmed by serologic tests, liver biopsy[] Leukopenia and thrombocytopenia are not uncommon.[] Infectious mononucleosis (IM) is a rare cause of aplastic anemia in adults.[] For excessive monocyte counts more generally, see monocytosis .[]

  • Hairy Cell Leukemia

    Abdominal discomfort is a common symptom, resulting from hepatosplenomegaly.[] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[] Here, we describe a patient with HCL who initially presented with pancytopenia and received a diagnosis of aplastic anemia.[] […] neoplastic hematopoietic disorders, such as lymphoma, myelodysplastic syndromes, multiple myeloma, aplastic anemia, severe megaloblastic anemia, severe lymphocytosis, severe monocytosis[]

  • Chronic Myelomonocytic Leukemia

    Hepatosplenomegaly (in most cases).[] Not having enough normal white blood cells (leukopenia) can lead to frequent or severe infections .[] Here is reported the case of an elderly woman that, after surgical intervention, showed an important anemia, leucocytosis and thrombocytopenia.[] The diagnosis of CMML requires absolute monocytosis ( 1000/μL) in addition to other criteria outlined by the World Health Organization (WHO) classification.(1) Monocytosis[]

  • Aggressive Systemic Mastocytosis

    The patient was a 37-week-old male, born by caesarean section owing to hepatosplenomegaly and ascites diagnosed in utero, who exhibited extensive cutaneous and systemic manifestations[] In fact, bone marrow failure is associated with cytopenias and patients suffering from anemia, leukopenia, or thrombocytopenia may present with pallor, weakness, and fatigue[] A rapidly progressive anemia and thrombocytopenia dictated a splenectomy.[] Respective clinical findings (so called C-Findings) include cytopenias, osteolysis (or osteoporosis) with pathologic fractures, hepatosplenomegaly with impaired liver function[]

  • Primary Myelofibrosis

    The main clinical manifestations of PMF are anemia, bleeding, hepatosplenomegaly, fatigue, and fever.[] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[] Most of them had anemia, fever, and hepatosplenomegaly on admission.[] […] malignant clone in PMF and are associated with unfavorable disease features and poor prognosis which is independent of currently established prognostic scoring system and monocytosis[]

  • Malaria

    A 5-year-old immunocompetent girl presented with fever, jaundice, hepatosplenomegaly and pancytopenia.[] Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients.[] AL treatment of severe malaria can cause delayed hemolytic anemia.[] Laboratory tests showed anaemia (haemoglobin 11.4 g/dl), severe thrombocytopaenia (platelets 30 10(9)/mm(3)), leukopenia (3650/mm(3)), lymphocytopenia (650/mm(3)).[]

  • Leukemia

    Hepatosplenomegaly and lymphadenopathy are rare in adults with acute myelogenous leukemia, but are present in about 50% of adults with acute lymphoblastic leukemia. 12 Central[] Common side effects of Besponsa include low levels of platelets (thrombocytopenia), low levels of certain white blood cells (neutropenia, leukopenia), infection, low levels[] The patient does not have an enlarged liver or spleen, anemia, or low levels of platelets.[] No other obvious cause for Leukocytosis (e.g. infection, Corticosteroid s) Step 1: Consider secondary causes based on white cell count differential Monocyte predominance (monocytosis[]

  • Gaucher Disease

    The hematologist is at the forefront of specialists to whom patients with Gaucher disease present because of cytopenia and hepatosplenomegaly.[] Decreased platelet counts (thrombocytopenia) as well as low hemoglobin (anemia) and decreased white blood cell counts (leukopenia) result in easy bruisability and hence black-and-blue[] A 38-year-old female patient was diagnosed with anemia for 3 years.[] The phenotype was unusually severe with congenital ichthyosis, hepatosplenomegaly, muscular hypotonia, myoclonus and respiratory failure.[]

  • Systemic Lupus Erythematosus

    Hepatosplenomegaly can come and go with disease activity.[] Drugs causing leukopenia Some drugs may lead to leukopenia.[] She was diagnosed with SLE with pernicious anemia and iron deficiency anemia. The rare association of SLE with pernicious anemia was reported previously in few patients.[] The most common laboratory finding was anemia, found in 22 (69%) of cases.[]

  • Brucellosis

    Brucellosis is a systemic zoonotic infectious disease that may cause fever, fatigue, sweating, arthritis, hepatosplenomegaly, cytopenia, and lymphadenopathy.[] Leukopenias associated with thrombocytopenia were observed. BMA showed to be normal.[] Also, Coombs-positive autoimmune hemolytic anemia as a result of the disease is comparatively rare when considering the other frequent hematologic complications.[] Anemia and leukopenia were defined as hemoglobin levels and leukocyte counts below the standard values in terms of ages, thrombocytopenia as thrombocyte counts below 150,000[]

Similar symptoms