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245 Possible Causes for Anemia, Hypopigmented Macule, Skin Patch

  • T-Cell Lymphoma

    One week after her first visit, hypoxemia, ascites, and Coomb test-positive autoimmune hemolytic anemia had newly appeared in addition to worsened fever, hepatosplenomegaly[ncbi.nlm.nih.gov] Early CTCL often lacks the histologic criteria necessary for a definitive diagnosis. 5 PVA presents as atrophic, hypopigmented and hyperpigmented macules and patches with[aafp.org] Many of these patients will have mild involvement in the skin (“patches” or “thin plaques”) with an excellent outcome and low likelihood of the skin condition worsening or[jamanetwork.com]

  • Klinefelter Syndrome

    In this manuscript, we report the first patient who suffered from Klinefelter syndrome with aplastic anemia and hyperprolactinemia.[ncbi.nlm.nih.gov] Early lesions which are erythematous/bullous evolve over time into warty lesions, hyperpigmented swirls/macules, and atrophic hypopigmented streaks.[ncbi.nlm.nih.gov] Testosterone is given by injection or through a skin patch or gel. The treatment usually continues throughout a man's life but does not help infertility .[cigna.com]

  • Cutaneous T-Cell Lymphoma

    Although several reports indicate the relationship between EF and hematological disorders such as aplastic anemia, polycythemia vera, or myelomonocytic leukemia, the association[ncbi.nlm.nih.gov] Early CTCL often lacks the histologic criteria necessary for a definitive diagnosis. 5 PVA presents as atrophic, hypopigmented and hyperpigmented macules and patches with[aafp.org] Early disease presents as limited skin patches or plaques and exhibits an indolent behavior.[ncbi.nlm.nih.gov]

  • Spondyloenchondrodysplasia

    We also noted that six individuals had clinical manifestations of autoimmunity (auto-immune thrombocytopenic purpura, auto-immune hemolytic anemia, auto-immune thyroiditis[ncbi.nlm.nih.gov] Phenotypes Autoimmune thrombocytopenia ; Autosomal recessive inheritance ; Cellular immunodeficiency ; Combined immunodeficiency ; Decrease in T cell count ; Hypermelanotic macule[mousephenotype.org] […] retardation and cerebral calcifications) or autoimmune manifestations, such as immune thrombocytopenic purpura, systemic lupus erythematosus (see these terms) hemolytic anemia[orpha.net]

  • Pityriasis Alba

    Iron deficiency anemia is also included in the theory behind the etiology of Pityriasis Alba.[healthh.com] Pityriasis alba (PA) is a relatively common skin disorder usually seen in children and young adults characterized by the presence of superficial hypopigmented macules.[ncbi.nlm.nih.gov] Pityriasis alba’s patches of white skin appear most frequently on the cheeks.[healthblurbs.com]

  • Amyloidosis

    CASE REPORT We present a case of gelsolin amyloidosis in a male of African descent with an atypical clinical presentation including fevers, skin rash, polyneuropathy, and anemia[ncbi.nlm.nih.gov] Hyperpigmented and hypopigmented macules on (A) lower legs, (B) back and waist, (C) waist.[en.wikipedia.org] , purple patches around the eyes, an irregular heartbeat or numbness/tingling or pain in the hands, feet or wrists.[houstonmethodist.org]

  • Dyskeratosis Congenita

    At King Faisal Specialist Hospital and Research Center, the most common entity referred for allogeneic hematopoietic cell transplantation (HCT) is Fanconi anemia, followed[ncbi.nlm.nih.gov] The hypopigmented macules showed no discernible erythema upon rubbing or the local application of heat.[ncbi.nlm.nih.gov] Dyskeratosis congenita (DC) is a rare genodermatosis characterised by a classic triad of dystrophic nails, reticular skin pigmentation and mucous membrane leukoplakic patches[ncbi.nlm.nih.gov]

  • Leprosy

    Twenty-four patients (3.2%) stopped dapsone intake due to adverse effects, of whom 16.6% due to severe anemia. One case of sulfone syndrome was reported.[ncbi.nlm.nih.gov] Features which may be seen in leprosy include: Skin lesions - hypopigmented macules and plaques (common), papules and nodules (rare) Neurological involvement - damage to small[patient.info] The multibacillary type has larger and more numerous skin nodules, and multiple skin patches, which often shows thickening, loss of sensation and lightening of skin coloration[news-medical.net]

  • Vitiligo

    (pernicious anemia), or thyroid disorders, including hyperthyroidism and hypothyroidism.[avrf.org] Vitiligo is signified by acquired white or hypopigmented macules or patches.[symptoma.com] In dark-skinned people the vitiligo patches are obvious since they contrast with normal skin.[drugs.com]

  • Cronkhite-Canada Syndrome

    A 54-year-old woman, diagnosed as MDS the prior year after evaluation of anemia, visited our hospital with the chief complaint of epigastric discomfort.[ncbi.nlm.nih.gov] macules or leukoderma on the palms, soles, upper limbs, chest Blisters Nail dystrophy ( onycholysis , koilonychia ) and onychomadesis (loss of nails ) Dry mouth and loss[dermnetnz.org] The signs and symptoms of Cronkhite-Canada Syndrome include: Alopecia (loss of hair) Abdominal pain and cramps Hyperpigmentation (large patches of dark spots on the skin or[dovemed.com]

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