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2,661 Possible Causes for Anemia, Leukopenia, Oral Ulcers, Thrombocytopenia

  • Chemotherapy

    The main outcomes were improvement in chemotherapy-induced grade 3/4 marrow suppression (leukopenia, neutropenia, anemia, and thrombocytopenia) or gastrointestinal toxicities[ncbi.nlm.nih.gov] Then, the oral ulcer disappeared and the HFS was controlled by dose adjustment, oral vitamin B6, and hand cream application.[ncbi.nlm.nih.gov] The patient presented with abdominal pain, haematochezia, acute anaemia and thrombocytopenia. CT of the abdomen and pelvis revealed SISBH.[ncbi.nlm.nih.gov] Hematological toxicities of Grade 3/4 were leukopenia 50%, neutropenia 68%, and febrile neutropenia 18%.[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    We are reporting a 4-year-old child who was received for investigation for persistent anemia, prolonged fever, and thrombocytopenia.[ncbi.nlm.nih.gov] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[ncbi.nlm.nih.gov] Because of the overlap between their symptoms, like oral ulcerations, skin lesions, arthritis and constitutional findings, HCL and BD may mimic each other.[ncbi.nlm.nih.gov] Here, we describe a patient with HCL who initially presented with pancytopenia and received a diagnosis of aplastic anemia.[ncbi.nlm.nih.gov]

  • Severe Aplastic Anemia

    She recovered completely, but her thrombocytopenia persisted. Six weeks later she became pancytopenic. A bone marrow aspirate and biopsy showed severe aplastic anemia.[ncbi.nlm.nih.gov] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[msdmanuals.com] Aplastic anemia is a rare, serious disease characterized by hypocellular bone marrow and pancytopenia in the peripheral blood.[ncbi.nlm.nih.gov] Stable mixed chimerism and mild thrombocytopenia, but no active hepatitis continued. At age 13, abdominal pain was a sign of massive tumor.[ncbi.nlm.nih.gov]

  • Hypersplenism

    The laparoscopic splenic vessels ligation is a feasible option for treating hypersplenism and thrombocytopenia in children.[ncbi.nlm.nih.gov] Unfortunately, these patients may become intolerant to this therapy when it is complicated by hypersplenism with leukopenia and/or thrombocytopenia.[ncbi.nlm.nih.gov] ulcerations . complications of References S u m m a r y Supervised by: Thank You hypersplenism 7 Differences between hypersplenism and other causes of pancytopenia Pancytopenia[prezi.com] Although splenomegaly in children with sickle cell anemia is common, massive enlargement associated with thrombocytopenia and very severe anemia is rare.[jamanetwork.com]

  • Vitamin B12 Deficiency

    […] lactate dehydrogenase, vasoconstriction, increased platelet aggregation, and abnormal activation of the coagulation followed by microangiopathy as well as neutropenia and thrombocytopenia[ncbi.nlm.nih.gov] He had a severe hypoproliferative megaloblastic anemia with hemolysis (hemoglobin 61g/L, mean corpuscular volume 99fL, reticulocytes 0.8%, haptoglobin undetectable), leukopenia[ncbi.nlm.nih.gov] The presence of oral signs and symptoms, including glossitis, angular cheilitis, recurrent oral ulcer, oral candidiasis, diffuse erythematous mucositis and pale oral mucosa[ncbi.nlm.nih.gov] There are many types of anemia. Vitamin B12 deficiency anemia is a low red blood cell count due to a lack (deficiency) of vitamin B12 .[mountsinai.org]

  • Acute Myelocytic Leukemia

    The clinical presentation was similar in all three, with acute onset of hepatomegaly and thrombocytopenia in the absence of significant transaminasemia or icterus.[ncbi.nlm.nih.gov] After completion of streptozotocin therapy, the patient had progressive leukopenia.[ncbi.nlm.nih.gov] However, it is not clear whether this autoantibody in AML patients induces frank hemolysis (autoimmune hemolytic anemia, AIHA), as seen in lymphoid neoplasms.[ncbi.nlm.nih.gov] During the postoperative course, both respiratory failure and severe thrombocytopenia progressed.[ncbi.nlm.nih.gov]

  • Congenital Acquired Immune Deficiency Syndrome

    Hepatitis Nephropathy Persistent fever lasting more than one month Neutropenia ( 1,000/µL), thrombocytopenia ( 100,000/µL) or anemia ( 8 g/dL).[symptoma.com] They both can present with a combination of symptoms including fevers, rashes, weight loss, joint pain, anemia, leukopenia, proteinuria, vasculitis, etc.[ped-rheum.biomedcentral.com] Resistant thrush, oral ulcers and conjunctivitis. Diarrhoea and malabsorption. Failure to thrive and delayed or incomplete recovery from illness. 7.[slideshare.net] The neonate had mild anemia but no other signs of congenital CMV infection.[experts.umn.edu]

  • Castleman Disease

    The side effects, essentially sustained thrombocytopenia, were mild in both cases.[ncbi.nlm.nih.gov] Grade- 3 AEs at least possibly attributed to siltuximab were leukopenia, lymphopenia, and a serious AE of polycythemia (n 1 each).[ncbi.nlm.nih.gov] A 36-year-old woman suffering from oral ulcerations, skin rash, and dyspnea was suspected of having paraneoplastic pemphigus.[ncbi.nlm.nih.gov] Laboratory findings were consistent with anemia of inflammation. Direct antiglobulin test was positive without any other evidence of autoimmune anemia.[ncbi.nlm.nih.gov]

  • Leukopenia

    […] risk of both leukopenia and thrombocytopenia.[ncbi.nlm.nih.gov] The prognosis of leukopenia depends upon the cause, duration of leukopenia, as well as age of the patient.[symptoma.com] However, serious cases can lead to oral ulcers, stomatitis, pneumonias and liver abscesses.[eatingdisorders.com] Anemia occurred in 87 (9.5%) subjects and leukopenia in 224 (22.9%).[ncbi.nlm.nih.gov]

  • Protein Losing Enteropathy

    The diagnosis of SLE was based on the presence of: malar rash, oral ulcers, thrombocytopenia, antinuclear antibodies, IgM anticardiolipin antibody, and lupus anticoagulant[ncbi.nlm.nih.gov] […] lesions 1 (6) Oral ulceration 1 (6) Fever 12 (75) Raynaud's phenomenon 5 (31) Cutaneous vasculitis 4 (25) Alopecia 2 (13) Proteinuria a 7 (44) Neuropsychiatric disease 2 (13) Leukopenia[academic.oup.com] Investigations revealed iron deficiency anemia which was treated with intravenous iron sucrose leading to resolution of both the anemia as well as symptoms of protein-losing[ncbi.nlm.nih.gov] Gastro-intestinal (GI) manifestations are oral ulcers, dysphagia and abdominal pain caused by autoimmune peritonitis/intestinal vasculitis.[ncbi.nlm.nih.gov]

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