Anhidrosis: Causes & Reasons

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Possible Causes for Anhidrosis

Horner's Syndrome

[…] rocigonzagua@gmail.com Abstract Horner's syndrome (oculosympathetic paresis) is characterised by the classic triad of ipsilateral palpebral ptosis, pupillary miosis and facial anhidrosis [ncbi.nlm.nih.gov]

Abstract Horner's syndrome is the triad of miosis, ptosis, and anhidrosis, resulting from disruption of the sympathetic pathways. [ncbi.nlm.nih.gov]

This classically produces a triad of signs including miosis, hemifacial anhidrosis and partial ptosis. [prep4medicine.com]

Ectodermal Dysplasia

Ectodermal dysplasias are rare conditions with a triad of hypotrichosis, anodontia and anhidrosis. [ncbi.nlm.nih.gov]

CASE REPORT: We describe a case of Allgrove Syndrome presenting with anhidrosis and peculiar dental features resembling those of Ectodermal Dysplasia (ED). [ncbi.nlm.nih.gov]

We could speculate that hypohidrosis or anhidrosis itself might impair skin barrier function and contribute to atopic diathesis. [ncbi.nlm.nih.gov]

Miliaria

Experimental production in volunteers. ( 6062874 ) SULZBERGER M.B....Wiley H.S. 1967 47 Miliaria and anhidrosis. II. [malacards.org]

Tropical anhidrotic asthenia is a skin condition, a rare form of miliaria, with long-lasting poral occlusion, which produces anhidrosis and heat retention. [en.wikipedia.org]

Anhidrosis develops in the affected sites and may last weeks. If generalized, anhidrosis can lead to hyperpyrexia and heat exhaustion. [emedicine.com]

Fabry Disease

Six patients sought consultation because of anhidrosis, considered of unclear cause, and angiokeratomas diagnosed as petechiae. [ncbi.nlm.nih.gov]

Dermal manifestations of Fabry disease include cutaneous vascular lesions (angiokeratomas) and abnormal sweating (anhidrosis or, more commonly, hypohidrosis). [emedicine.medscape.com]

Anhidrosis or hypohidrosis may occur causing heat and exercise intolerance. [orpha.net]

Dysautonomia

Management[edit] The treatment options for hypohidrosis and anhidrosis is limited. [en.wikipedia.org]

For example, in Sj ö gren syndrome, dry mouth and eyes along with anhidrosis are typically the initial symptoms in affected patients. [emedicine.medscape.com]

Idiopathic causes: chronic idiopathic anhidrosis. [patient.info]

Thallium Poisoning

[…] poisoning, Mees lines (transverse white lines on the nails) appear in the nail plate. [22] Other dermatologic findings include crusted eczematous lesions, hypohidrosis, anhidrosis [emedicine.medscape.com]

[…] nails) appear in the nail plate. [22] Other dermatologic findings include well-demarcated hyperkeratosis of the palms and soles, crusted eczematous lesions, hypohidrosis, anhidrosis [emedicine.medscape.com]

Other findings may include crusted eczematous lesions, hypohidrosis (reduced sweating), anhidrosis (absence of sweating), palmar erythema, painful glossitis (sore tongue) [dermnetnz.org]

Diabetic Neuropathy

(up to 20%) Dysphagia with delayed gastric emptying, nausea/vomiting Constipation/diarrhoea Urinary retention/overflow incontinence Neuropathic oedema Gustatory sweating Anhidrosis [nhshighland.scot.nhs.uk]

Gustatory sweating, anhidrosis. Tends to be associated with peripheral neuropathy. People with both types 1 and 2 are affected. [patient.info]

Hypotension

[…] parkinsonian features cerebellar ataxia weight loss resting tachycardia or impaired heart rate variation abnormal GI motility erectile dysfunction and lack of ejaculation anhidrosis [online.epocrates.com]

[…] evaluation might involve an autonomic reflex screen (to evaluate adrenergic, sudomotor and cardiovagal function), thermoregulatory sweat test (to evaluate the distribution of anhidrosis [rarediseases.org]

A sweat test showed about 50% anhidrosis. Norepinephrine level was about 30 units lower supine than upright. [dizziness-and-balance.com]

Urticaria

Watanabe, Treatment of patients with acquired idiopathic generalized anhidrosis, British Journal of Dermatology, 168, 2, (430-432), (2012). Valerie A. [doi.org]

Small wheals on the skin, especially in any areas scratched during the reaction General Anhidrosis, or reduced sweating ability. [cholinergicurticaria.net]

Nishigori, Steroid treatment can improve the impaired quality of life of patients with acquired idiopathic generalized anhidrosis, British Journal of Dermatology, 172, 2, [doi.org]

Brachial Plexus Injury

[…] commonly in brachial plexus injuries, resulting, respectively, in ipsilateral diaphragmatic paralysis and Horner syndrome (miosis, partial ptosis, slight enophthalmos and anhidrosis [pedsinreview.aappublications.org]

Review Topic QID: 4750 1 The injury has likely resulted in the avulsion of several nerve roots 2 Physical exam would likely reveal drooping of his left eyelid and anhidrosis [orthobullets.com]

Avulsion or damage of the C8 and T1 nerve roots from which the cervical sympathetic chain arises cause Horner syndrome, which is characterized by ptosis, meiosis, anhidrosis [thenerve.net]

Lumbosacral Plexus Disorder

Earlier in the course of autonomic neuropathy, patients might notice reduced or absent sweating (i.e., anhidrosis) often in a distal-to-proximal gradient. [clevelandclinicmeded.com]

This is most often secondary to anhidrosis in the limbs and thorax and reflects compensatory hyperhidrosis in the restricted areas that maintain normal sweating. [clevelandclinicmeded.com]

Hypothyroidism

It results in mental deficiency. hypothyroidism diminished thyroid hormone production and symptoms of thyroid insufficiency (e.g. generalized anhidrosis) hypothyroidism, n [medical-dictionary.thefreedictionary.com]

Adie Syndrome

Tonic pupil, areflexia, and segmental anhidrosis: two additional cases of Ross syndrome and review of the literature Michael Weller, Helmut Wilhelm, Norbert Sommer, Johannes [semanticscholar.org]

Diabetic Peripheral Neuropathy

Gustatory sweating, anhidrosis. Tends to be associated with peripheral neuropathy. People with both types 1 and 2 are affected. [patient.info]

Leprosy

Skin denervation leads to anhidrosis and poor autonomic function, as a result of which ulceration and secondary infection occurs. [news-medical.net]

[…] lesions - hypopigmented macules and plaques (common), papules and nodules (rare) Neurological involvement - damage to small nerves to the skin, producing reduced sensation and anhidrosis [patient.info]

With time, the peripheral anesthesia becomes extensive and there is almost complete anhidrosis of the limbs. [internationaltextbookofleprosy.org]

Hereditary ATTR Amyloidosis

Other system involvement Autonomic nervous system involvement includes anhidrosis, sexual impotence, disturbances of gastrointestinal motility (most commonly diarrhea alternating [ncbi.nlm.nih.gov]

Stroke

Beyond F.A.S.T. – Other Symptoms You Should Know Sudden NUMBNESS or weakness of face, arm, or leg, especially on one side of the body Sudden CONFUSION, trouble speaking or understanding speech Sudden TROUBLE SEEING in one or both eyes Sudden TROUBLE WALKING, dizziness, loss of balance or coordination Sudden[…] [strokeassociation.org]

Malignant Neoplasm of the Lung

A primary or metastatic malignant neoplasm involving the lung. [from NCI ] Etiology Eur J Cardiothorac Surg 2017 Dec 1;52(6):1041-1048. doi: 10.1093/ejcts/ezx272. PMID: 28950348 Behr J, Bendstrup E, Crestani B, Günther A, Olschewski H, Sköld CM, Wells A, Wuyts W, Koschel D, Kreuter M, Wallaert B, Lin CY, Beck J, Albera C[…] [ncbi.nlm.nih.gov]

Hashimoto Thyroiditis

History Hypothyroidism is usually insidious in onset, with signs and symptoms slowly progressing over months to years. Most commonly, patients do not relate a history suggestive of transient hyperthyroidism secondary to increased T4 and T3 levels resulting from thyrocyte destruction. The time course is influenced[…] [emedicine.medscape.com]

Plant Poisoning

Overview Practice Essentials More than 270 plant species have been identified as having hypoglycemic potential. Many of these plants are used in developing countries in the treatment of diabetes. The most well known of these plants are listed below: Herb fenugreek ( Trigonella foenum-graecum ) Bitter melon gourd ([…] [emedicine.medscape.com]

Autonomic Neuropathy

1型遺伝性感覚性自律神経性ニューロパチー 4型遺伝性感覚性自律神経性ニューロパチー Autosomal Dominant Neuropathy Hereditary Sensory Radicular Congenital Insensitivity to Pain with Anhidrosis Congenital Pain Insensitivity [lsd-project.jp]

Abstract We describe a case of hereditary sensory and autonomic neuropathy (HSAN) type II in a child with a penetrating foot ulcer, acral sensory impairment, and anhidrosis [ncbi.nlm.nih.gov]

We report on a 10-year-old girl with anhidrosis and insensibility to pain, but no severe mental retardation or self-mutilation, diagnosed as hereditary sensory and autonomic [ncbi.nlm.nih.gov]

Systemic Scleroderma

BACKGROUND: Patients with systemic scleroderma exhibit a noticeable slowing of blood cell velocities or even stasis in the capillaries of the skin. In this study the effects of transdermally applied prostaglandin PGE1 ethyl ester on nutritive cutaneous perfusion and on Raynaud's symptoms were investigated. PATIENTS[…] [ncbi.nlm.nih.gov]

Aortic Aneurysm

Ann Thorac Surg. 2017 May;103(5):e437-e440. doi: 10.1016/j.athoracsur.2016.10.013. Author information 1 Department of Cardiovascular Surgery, Okamura Memorial Hospital, Shizuoka, Japan. Electronic address: hmr0705m@gmail.com. 2 Department of Cardiovascular Surgery, Okamura Memorial Hospital, Shizuoka, Japan. 3 Department[…] [ncbi.nlm.nih.gov]

Peroneal Nerve Paralysis

Abstract Adequate hemostasis is extremely important in extensor reconstruction of the knee and possibly all knee injury. Hemarthrosis postoperatively contributes to postoperative discomfort and may increase the risk of infection. Hematoma formation is also responsible for neurovascular complications. Peroneal[…] [ncbi.nlm.nih.gov]

Hereditary Sensory Neuropathy

Anhidrosis. [ncbi.nlm.nih.gov]

Sweat gland investigations showed significant hypohidrosis or anhidrosis although the sweat glands were normal microscopically. [ncbi.nlm.nih.gov]

Anhidrosis was documented by the starch-iodine test. [ijpd.in]

Harlequin Syndrome

Bilateral Adie's tonic pupil with anhidrosis and hyperthermia. Arch Neurol 1984; 41 : 342–343. PubMed Google Scholar 12. Vanasse M, Molina-Negro P, Saint-Hilaire JM. [link.springer.com]

The result is usually unilateral lack of flushing and anhidrosis [ 2 ] ( Figure 1 ). [ncbi.nlm.nih.gov]

This was thought to be due to Ross’s syndrome (Adie’s syndrome with anhidrosis). [doi.org]

Tonic Pupil

Two patients are described with the triad of tonic pupil, hyporeflexia and segmental anhidrosis (Ross syndrome). [ncbi.nlm.nih.gov]

Faden AI, Chan P, Mendoza E (1982) Progressive isolated segmental anhidrosis. Arch Neurol 39:172–175 PubMed Google Scholar 5. [link.springer.com]

Full Text Introduction In 1958, Alexander Ross described a case with anhidrosis and Adie's syndrome. [journalofoptometry.org]

Neurological Disorder

There is ample evidence that pinpoints neurological disorders as one of the greatest threats to public health. There are several gaps in understanding the many issues related to neurological disorders, but we already know enough about their nature and treatment to be able to shape effective policy responses to[…] [who.int]

Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

CLINICAL REPORT Anesthesia in a patient with congenital insensitivity to pain and anhidrosis Anestesia en paciente con insensibilidad congénita al dolor y anhidrosis Carlos [scielo.br]

Congenital — Congenital Insensitivity to Pain with Anhidrosis — Hereditary Sensory Autonomic Neuropathy, Type 4 — HSAN 4 — Insensitivity to Pain, Congenital, with Anhidrosis [mesh.kib.ki.se]

Anhidrosis was documented by the starch-iodine test. [ijpd.in]

Channelopathy-Associated Congenital Insensitivity to Pain

Congenital insensitivity to pain with anhidrosis. [pediatricneurosciences.com]

Symptoms Symptoms of Congenital insensitivity to pain with anhidrosis appear usually at birth or during infancy. [flipper.diff.org]

Congenital insensitivity to pain and anhidrosis. [ijoonline.com]