Anisocoria: Causes & Reasons

Possible Causes for Anisocoria

The causes of anisocoria are diverse and varied. Traditionally, physiologic anisocoria shows equal asymmetry in light and dark conditions. [emedicine.medscape.com]

Our case is highlighted by the initial presentation of an isolated anisocoria, initially believed to represent an Adie's tonic pupil as interpreted by pharmacologic testing [ncbi.nlm.nih.gov]

[…] may have simple anisocoria secondary to the effect of certain drugs eg. pseudo-ephedrine or serotonin reuptake inhibitors, and the anisocoria (like physiological anisocoria [lifeinthefastlane.com]

Anisocoria

Anisocoria is unequal pupil sizes. Anisocoria itself does not cause symptoms. [merckmanuals.com]

Degree of anisocoria is about the same in the dark. [webeye.ophth.uiowa.edu]

The small pupil is abnormal if the anisocoria is worse in the dark and the larger pupil is abnormal if the anisocoria is worse in the light when compared to dark conditions [symptoma.com]

Triple A Syndrome

No hypotonia optic atrophy, ataxia, microcephaly M Both Same No Dumic (1987) [11] M Glucocorticoid Sensory Hyperkeratosis of palms polyneuropathy, and soles, insufficient anisocoria [hon.ch]

[…] severity of neurologic and autonomic dysfunction in Triple-A syndrome is quite variable, including hyperreflexia, impaired visual evoked potentials, optic nerve atrophy, anisocoria [genedx.com]

People with triple A syndrome often experience abnormal sweating, difficulty regulating blood pressure, unequal pupil size (anisocoria), and other signs and symptoms of autonomic [ghr.nlm.nih.gov]

Exfoliation Syndrome

Anisocoria, Physiologic (Anisocoria) Anisometropia Anisometropic Amblyopia (Amblyopia) Anophthalmia (Anophthalmos) Anophthalmos Anterior Ischemic Optic Neuropathy (Optic [provisu.ch]

Allergic) Amaurosis Fugax Amaurosis (Blindness) Amblyopia Ametropia (Refractive Errors) Angiogenesis, Corneal (Corneal Neovascularization) Angioid Streaks Aniridia Aniseikonia Anisocoria [provisu.ch]

Intracranial Hemorrhage

Initial emergency room evaluation found the patient to have anisocoria with a fixed and dilated right pupil and demonstrated evidence of decorticate posturing. [ncbi.nlm.nih.gov]

There were 4 hours after patient back to neurosurgical intensive care unit (NICU), patient appeared anisocoria (R/L:4.0/2.5 mm), bilateral light reflexes disappeared, then [ncbi.nlm.nih.gov]

[…] may include the following: [ citation needed ] Hypertension, fever, or cardiac arrhythmias Nuchal rigidity Subhyaloid retinal hemorrhages Altered level of consciousness Anisocoria [en.wikipedia.org]

Coma

He was managed nonoperatively and discharged with a Glasgow Coma Scale score of 15, only to return 3 days later with obtundation, fixed downward gaze, anisocoria, and absent [ncbi.nlm.nih.gov]

[…] computed tomography, CTA computed tomography angiography, EEG electroencephalogram, SAH Subarachnoid hemorrhage The Coma Neuro Exam Carefully examine the eyes (Vertical Skew, Anisocoria [emcrit.org]

If one pupil is dilated, other causes of anisocoria should be considered; they include past ocular trauma, certain headaches, and use of a scopolamine patch (if the drug comes [merckmanuals.com]

Alacrima - Achalasia - Mental Retardation

People with triple A syndrome often experience abnormal sweating, difficulty regulating blood pressure, unequal pupil size (anisocoria), and other signs and symptoms of autonomic [ghr.nlm.nih.gov]

More variable features include hypotonia, gait abnormalities, anisocoria, and visual or hearing deficits. [mendelian.co]

Brain Stem Herniation

and 2.2 to 2.4 gm/kg if they had anisocoria. [neupsykey.com]

Preoperative improvement in anisocoria was also significantly better in the high-dosage group. [neupsykey.com]

Of the 7 patients with an initial SBP of less than 60 mm Hg, 2 (29%) had anisocoria, all had absent corneal reflexes, and all were flaccid. [neupsykey.com]

Subdural Hematoma

The period from losing consciousness to brain herniation presenting as anisocoria was very short-only 30 minutes in our patient. [ncbi.nlm.nih.gov]

But the CT after 48 hours showed edema around the contusion and uncal herniation with anisocoria (Figure 2(b)). [hindawi.com]

Anisocoria was present in 7.5% of patients on admission. [scielo.br]

Stroke

Decreased levels of consciousness, hypertension, bradycardia and anisocoria may indicate a pathological rise of intracranial pressure due to cerebral edema. [symptoma.com]

Traumatic Brain Injury

[…] or is slow to do so.[50] Cushing's triad, a slow heart rate with high blood pressure and respiratory depression is a classic manifestation of significantly raised ICP.[9] Anisocoria [en.wikipedia.org]

Paradoxical Embolism

Increased neurological distress was suggested by anisocoria with areactive left mydriasis and body‑part pyramidal syndrome. [docksci.com]

Intracranial Hypertension

At the beginning of uncal herniation, indicated by anisocoria, the mean 1-CBF of the IC abruptly decreased from 33.7 to 19.6 ml/100g/min (n=16). [ousar.lib.okayama-u.ac.jp]

Varicella

[…] cataracts, chorioretinitis, optic atrophy Other neurological disorder: damage to cervical and lumbosacral spinal cord, motor/sensory deficits, absent deep tendon reflexes, anisocoria [en.wikipedia.org]

Brain Concussion

A concussion is an injury to the brain that results in temporary loss of normal brain function. It usually is caused by a blow to the head. In many cases, there are no external signs of head trauma. Many people assume that concussions involve a loss of consciousness, but that is not true. In many cases, a person[…] [aans.org]

Diabetic Autonomic Neuropathy

BACKGROUND: Diabetic autonomic neuropathy (DAN) results in increased morbidity and mortality. The early diagnosis of DAN can be difficult and is commonly evaluated using cardiac autonomic function tests as a surrogate. However, they are not widely available, have limited sensitivity and specificity, and can be[…] [ncbi.nlm.nih.gov]

Cervical Spondylosis

[…] stockdevil_666 7212 x 5384 stockdevil_666 3421 x 5131 imagepointfr 2620 x 3930 stockdevil_666 4327 x 6401 imagepointfr 2620 x 3930 imagepointfr 2620 x 3930 stockdevil_666 3668 x 3668 stockdevil_666 3432 x 4210 imagepointfr 2620 x 3930 stockdevil_666 6000 x 4000 stockdevil_666 3421 x 5131 Draw05 2250 x 2746[…] [sp.depositphotos.com]

Cluster Headache

Abstract Cluster headache is a rare disorder that is more common in adult male patients. It has a unique phenotype of unilateral, severe, to very severe headaches lasting 15 to 180 min with ipsilateral autonomic symptoms. Time to correct diagnosis can be protracted. A number of treatment options exist for the[…] [ncbi.nlm.nih.gov]

Migraine without Aura

Abstract The effect of 30 min voluntary toothclenching was studied in 48 patients with common migraine, randomized in two groups. Group 1 performed low-level tension at 5% and group 2, high-level tension at 30% of the individual maximum, as judged by surface EMG from the temporal muscle. Pericranial muscle[…] [ncbi.nlm.nih.gov]

Brain Neoplasm

Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring[…] [ncbi.nlm.nih.gov]

Multiple Sclerosis

Dr. Carla Rossotti (left), a general practitioner, and her health care team leave the home of the their patient, 37-year-old Osvaldo Daniel Martinez. He has the symptoms of a degenerative disease, Rossotti says, but he needs a neurologist's evaluation before he can get proper treatment. Sarah Varney/Kaiser Health[…] [npr.org]

Guillain-Barré Syndrome

Home British & World English Guillain–Barré syndrome Guillain–Barré syndrome noun mass noun Medicine An acute disorder of the peripheral nerves, often preceded by a respiratory infection, causing weakness and often paralysis of the limbs. Origin 1916: named after Georges Guillain (1876–1961) and Jean Barré[…] [en.oxforddictionaries.com]

Postictal State

Epilepsy Behav. 2010 Oct;19(2):146-50. doi: 10.1016/j.yebeh.2010.06.022. Epub 2010 Aug 14. Author information 1 Columbia Comprehensive Epilepsy Center, New York, NY 10032, USA. cwb11@columbia.edu Abstract The postictal state can be particularly confusing when occurring in association with sleep. Some seizures tend to occur[…] [ncbi.nlm.nih.gov]

Ophthalmic Nerve Disorder

Anisocoria, Physiologic (Anisocoria) Anisometropia Anisometropic Amblyopia (Amblyopia) Anophthalmia (Anophthalmos) Anophthalmos Anterior Ischemic Optic Neuropathy (Optic [provisu.ch]

Differential diagnosis Anisocoria: Essential anisocoria Adie pupil (long-standing) Argyll-Robertson pupil Chronic anterior uveitis Pupillary sphincter tear Unilateral use [eyewiki.org]

Physical exam revealed a non-obese woman with anisocoria with the right pupil dilated and slightly less reactive to light than the left pupil. [healio.com]

Oculomotor Nerve Paralysis

Anisocoria, Physiologic (Anisocoria) Anisometropia Anisometropic Amblyopia (Amblyopia) Anophthalmia (Anophthalmos) Anophthalmos Anterior Ischemic Optic Neuropathy (Optic [provisu.ch]

Anisocoria. The Eyes Have It. University of Michigan Kellogg Eye Center http://www.kellogg.umich.edu/theeyeshaveit/symptoms/anisocoria.html 5. [neuro-ophthalmology.stanford.edu]

Malaria

What Are the Different Types of Malaria Parasites? Five species of Plasmodium (single-celled parasites) can infect humans and cause illness: Plasmodium falciparum (or P. falciparum) Plasmodium malariae (or P. malariae) Plasmodium vivax (or P. vivax) Plasmodium ovale (or P. ovale) Plasmodium knowlesi (or P. knowlesi)[…] [stanfordhealthcare.org]

Fibromuscular Dysplasia

ICD-10-CM Codes › I00-I99 Diseases of the circulatory system › I70-I79 Diseases of arteries, arterioles and capillaries › I77- Other disorders of arteries and arterioles › Arterial fibromuscular dysplasia 2016 2017 2018 2019 Billable/Specific Code I77.3 is a billable/specific ICD-10-CM code that can be used to indicate a[…] [icd10data.com]

Horner's Syndrome

Anisocoria that is NOT associated with or due to an underlying medical condition is called physiologic anisocoria. [aapos.org]

In these topics Anisocoria [msdmanuals.com]

Approximately 20% of the population has anisocoria. The amount of anisocoria can vary from day-to-day and can even switch eyes. [aapos.org]

Holmes-Adie Syndrome

Background Anisocoria, or unequal pupil sizes, is a common condition. [emedicine.medscape.com]

Anisocoria. American Academy of Ophthalmology. EyeSmart® Eye health. https://www.aao.org/eye-health/diseases/anisocoria-5. Accessed November 17, 2022. [eyewiki.aao.org]

Pharmacological testing of anisocoria. [scielo.br]

Zygadenus Poisoning

Toxicoscordion paniculatum. Synonym : Zigadenus paniculatus. (Desert Death Camas) Melanthiaceae (False Hellebore Family) formerly Liliaceae (Lily Family) Semi-desert, foothills. Openings, woodlands, shrublands. Spring. Butler Wash, Utah, April, 22, 2015. Toxicoscordion paniculatum, Toxicoscordion venenosum, and Anticlea[…] [swcoloradowildflowers.com]