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26 Possible Causes for Anisocoria, Severe Peripheral Motor Neuropathy, Slow Pulse

  • Diabetic Autonomic Neuropathy

    Bradycardia did not respond to atropine. Postoperative autonomic nervous function tests showed advanced autonomic neuropathy.[ncbi.nlm.nih.gov] Diabetic autonomic neuropathy is a subgroup of diabetic neuropathy, a group of nerve diseases affecting the peripheral nerves outside the brain and spinal cord.[columbianeurology.org] Cardiac autonomic neuropathy (CAN) has been linked to resting tachycardia, postural hypotension, orthostatic bradycardia and orthostatic tachycardia (POTTS), exercise intolerance[ncbi.nlm.nih.gov]

  • Diphtheria

    Adverse Event: Six hours after starting midazolam infusion he started developing pulsus bigeminus and bradycardia and eventual death after two hours.[ncbi.nlm.nih.gov] Systemic absorption of the toxin can result in acute renal failure, neuropathy (cranial, palatal or peripheral motor) and cardiomyopathy, resulting in early death or later[www2.health.vic.gov.au] Heart Damage : Diphtheria toxins can cause inflammation of heart muscles (myocarditis), slow heartbeat (bradycardia), congestive heart failure, or sudden death.[immunizationinfo.com]

  • Guillain-Barré Syndrome

    He subsequently developed severe bradycardia and refractory hypotension, which initially responded to dopamine infusion.[ncbi.nlm.nih.gov] Acute Motor Axonal Neuropathy (AMAN) No sensory deficits Associated with epidemics following C. jejuni enteritis.[pedemmorsels.com] Sensory nerve involvement (80%) Pain (90%) Parenthesis, numbness and tingling Loss vibratory, touch, and pain sensation Ataxia Autonomic system involvement Tachycardia and bradycardia[symptoma.com]

  • Acute Pandysautonomia

    A 33-year-old white man developed premature presbyopia and anisocoria as initial manifestations of acute pandysautonomia.[ncbi.nlm.nih.gov] . • Clinical variants may include associated encephalitis, sensory or sensorimotor neuropathy, and segmental autonomic disorders such as isolated ileus, unexplained bradycardia[medlink.com] […] demyelinating neuropathy motor as well as sensory component and responding to IVIG.[ispub.com]

  • Neuropathy

    Anisocoria and impaired pupillary light reflexes indicate parasympathetic damage and may be isolated, as in Adie’s syndrome, or direct a more careful search for autonomic[jnnp.bmj.com] […] abdominal pain, nausea, vomiting, malabsorption, fecal incontinence, gastroparesis, diarrhoea, constipation Cardiovascular system: disturbances of heart rate (tachycardia, bradycardia[en.wikipedia.org] Traumas, such as from motor vehicle accidents, falls or sports injuries, can sever or damage peripheral nerves.[mayoclinic.org]

  • Ophthalmoplegia

    Ophthalmoplegia reversed much earlier and more significantly when compared to anisocoria.[ijo.in] This week, we are doing another crossover episode, in which we return to cardiac arrhythmias — specifically, bradycardia.[roshreview.com] Peripheral neuropathy may affect sensory, motor, reflex, or blood vessel function.[rarediseases.org]

  • Miller-Fisher Syndrome

    Hadjivassiliou M. 2015 45 Miller-Fisher syndrome associated with unilateral cerebral white matter lesions. ( 26377988 ) Xu Y....Liu L. 2015 46 Atypical Miller Fisher Syndrome with Anisocoria[malacards.org] We report a case of MFS with severe bradycardia and asystole treated initially with an external permanent (temporary-permanent) pacemaker with a transvenous, active fixation[ncbi.nlm.nih.gov] In addition to peripheral neuropathy CNS involvement, exclusive or more marked in posterior fossa, occurs not infrequently.[moh-it.pure.elsevier.com]

  • Spastic Ataxia with Congenital Miosis

    Differential diagnosis Anisocoria: Essential anisocoria Adie pupil (long-standing) Argyll-Robertson pupil Chronic anterior uveitis Pupillary sphincter tear Unilateral use[eyewiki.aao.org] On the side of the cardiovascular sy stem: temporary bradycardia, tachycardia, arrhythmia, heart rate, tides.[onhealthing.com] Patients may initially present with predominant peripheral neuropathy or with seizures.[clinicalgate.com]

  • Chronic Progressive External Ophthalmoplegia

    Anisocoria, Physiologic (Anisocoria) Anisometropia Anisometropic Amblyopia (Amblyopia) Anophthalmia (Anophthalmos) Anophthalmos Anterior Ischemic Optic Neuropathy (Optic[provisu.ch] […] muscle weakness, cataracts and migraine 48 62 None COX deficient/no RRF LRPCR c.671T G p.Ile224Ser 6 No 9 Severe PEO, ptosis, mild dysphagia, fatigue, ataxia, glaucoma, bradycardia[doi.org] Peripheral neuropathy may affect sensory, motor, reflex, or blood vessel function.[rarediseases.org]

  • Peripheral Motor Neuropathy

    Anisocoria and impaired pupillary light reflexes indicate parasympathetic damage and may be isolated, as in Adie’s syndrome, or direct a more careful search for autonomic[jnnp.bmj.com] […] abdominal pain, nausea, vomiting, malabsorption, fecal incontinence, gastroparesis, diarrhoea, constipation Cardiovascular system : disturbances of heart rate ( tachycardia, bradycardia[en.wikipedia.org] peripheral neuropathy primarily affecting motor neurons.[ncbi.nlm.nih.gov]

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