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95 Possible Causes for Anisopoikilocytosis, Microcytic Anemia

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  • Thalassemia

    Blood analysis shows reduced Hb levels ( 7 g/dl), mean corpuscular volume (MCV) 50 70 fl, and mean corpuscular Hb (MCH) 12 20 pg, anisopoikilocytosis and presence of erythroblasts[orpha.net] On the basis of limited descriptions in the literature, the disease is reported as a mild microcytic anemia with an uncomplicated course.[ncbi.nlm.nih.gov] Peripheral smear shows target cells, teardrop RBCs, polychromasia, moderate anisopoikilocytosis, and basophilic stippling.[clinicaladvisor.com]

  • Sideroblastic Anemia

    Showing marked anisopoikilocytosis, basophilic stippling, polychromasia and nRBCs.[imagebank.hematology.org] The characteristic hypochromic, microcytic anemia typically becomes manifest in the first three decades of life.[ncbi.nlm.nih.gov] Sideroblastic anemia is a rare cause of microcytic hypochromic anemia.[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disease characterized by congenital hypochromic microcytic anemia, low transferrin saturation,[ncbi.nlm.nih.gov] Patients have hypochromic microcytic anemia refractory to oral iron and are only partially responsive to parenteral iron administration.[ncbi.nlm.nih.gov] The biological assessment initially showed a profound microcytic, aregenerative, iron deficiency anemia.[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Red cell morphology in the peripheral blood may be normal or macrocytic with anisopoikilocytosis.[clinicaladvisor.com] Patients have a microcytic anemia with very low transferrin saturation and are refractory to oral iron.[merckmanuals.com] These are pale and small and are called microcytic RBCs.[news-medical.net]

  • Haemoglobin E Disease

    Aggarwal et al also [6] found microcytic hypochromic picture with anisopoikilocytosis in HbE trait.[medresearch.in] In homozygotes, a mild microcytic anemia with prominent target cells exists. Diagnosis of Hb E disorders is by Hb electrophoresis.[merckmanuals.com] The peripheral blood picture showed severe anisopoikilocytosis of the red blood cells (RBCs) with the presence of a fair number of microcytes, target cells, tear drop cells[jdrntruhs.org]

  • Extramedullary Hematopoiesis

    […] granulocyte and megakaryocytic series along with fibrillary and adipose elements Click here to view Further confirmation done by the peripheral blood film, which showed mild anisopoikilocytosis[lungindia.com] Her admission workup showed microcytic anemia.[ncbi.nlm.nih.gov] Her past medical history was significant for chronic anemia. Physical examination revealed a pansystolic murmur radiating to the left axilla.[ncbi.nlm.nih.gov]

  • Chediak Higashi Syndrome

    Peripheral blood smear showed anisopoikilocytosis, microcytic anemia and pancytopenia. Giant granules were present in the neutrophils granulocytes and eosinophils.[slideshare.net] Peripheral blood smear showed anisopoikilocytosis, microcytic anemia and pancytopenia. Giant granules were present in the neutrophils granulocytes and eosinophils.[slideshare.net]

  • Refractory Anemia

    There can also be abnormal platelets (large, giant or hypogranular) and red cell anisopoikilocytosis. Blasts are commonly present.[imagebank.hematology.org] Microcytic anemia refractory to usual supplementation is an important clue to an alternative diagnosis.[ncbi.nlm.nih.gov] […] prognostic group Median survival is 16-40 months RAEB-2 High-risk group Median survival is 9-20 months MICROSCOPIC PATHOLOGY Cytologic Features Peripheral blood Anemia with anisopoikilocytosis[basicmedicalkey.com]

  • Microcytosis

    MD What does Milld hypochromasia microcytosis anisopoikilocytosis with ovalocytes means ... MD . Mild microcytosis .[healthcaremagic.com] Anemia need not be present. If there is an anemia, the anatomical diagnosis is “microcytic anemia”; otherwise, it is “a microcytic red cell picture.” ...[link.springer.com] Iron deficiency anemia is the most common type of anemia in microcytosis patients, followed by TT-induced anemia and other microcytic anemia.[ncbi.nlm.nih.gov]

  • Beta Thalassemia

    Peripheral smear from a patient with beta-zero thalassemia major showing more marked microcytosis (M) and anisopoikilocytosis (P) than in thalassemia minor.[emedicine.medscape.com] Clinical signs were compatible with severe microcytic anemia requiring bi-monthly blood transfusions.[ncbi.nlm.nih.gov] Peripheral blood smear Red blood cells (RBCs) can be hypochromic and there can be marked microcytosis and anisopoikilocytosis, target cell formation and basophilic stippling[clinicaladvisor.com]

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