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76 Possible Causes for Anisopoikilocytosis, Microcytic Anemia

  • Iron Deficiency Anemia

    Abstract Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disease characterized by congenital hypochromic microcytic anemia, low transferrin saturation[ncbi.nlm.nih.gov] Patients have hypochromic microcytic anemia refractory to oral iron and are only partially responsive to parenteral iron administration.[ncbi.nlm.nih.gov] ; iron deficiency anemia; microcytic anemia; β-Thalassemia (β-thal)[ncbi.nlm.nih.gov]

  • Thalassemia

    Blood analysis shows reduced Hb levels ( 7 g/dl), mean corpuscular volume (MCV) 50 70 fl, and mean corpuscular Hb (MCH) 12 20 pg, anisopoikilocytosis and presence of erythroblasts[orpha.net] On the basis of limited descriptions in the literature, the disease is reported as a mild microcytic anemia with an uncomplicated course.[ncbi.nlm.nih.gov] Peripheral smear from a patient with beta-zero thalassemia major showing more marked microcytosis (M) and anisopoikilocytosis (P) than in thalassemia minor.[emedicine.medscape.com]

  • Hemoglobin Bart's Disease

    Peripheral smear shows target cells, teardrop RBCs, polychromasia, moderate anisopoikilocytosis, and basophilic stippling.[clinicaladvisor.com] Microcytic anemia is characterized by smaller-than-normal red cells due to decreased production of hemoglobin.[nejm.org] -Mild, microcytic, hypochromic anemia and splenomegaly.[quizlet.com]

  • Myelodysplasia

    Red cell morphology in the peripheral blood may be normal or macrocytic with anisopoikilocytosis.[clinicaladvisor.com] Patients have a microcytic anemia with very low transferrin saturation and are refractory to oral iron.[merckmanuals.com] Patients with XLSA had a microcytic congenital anemia associated with the presence of ringed sideroblasts in the bone marrow.[doi.org]

  • Sideroblastic Anemia

    Showing marked anisopoikilocytosis, basophilic stippling, polychromasia and nRBCs.[imagebank.hematology.org] The characteristic hypochromic, microcytic anemia typically becomes manifest in the first three decades of life.[ncbi.nlm.nih.gov] Abstract Sideroblastic anemia is a rare cause of microcytic hypochromic anemia.[ncbi.nlm.nih.gov]

  • Thalassemia Minor

    Peripheral smear from a patient with beta-zero thalassemia major showing more marked microcytosis (M) and anisopoikilocytosis (P) than in thalassemia minor.[emedicine.medscape.com] Abstract Iron deficiency anemia (IDA) and thalassemia minor are two of the most common causes of microcytic anemias worldwide.[ncbi.nlm.nih.gov] The peripheral smear showed hypochromic, microcytic anemia with poikilocytes and target cells. Sickling was absent and osmotic fragility was decreased.[jpgmonline.com]

  • Microcytic Anemia

    The peripheral smear generally reveals hypochromic red cells with significant anisopoikilocytosis, which is reflected in a high red cell distribution width (RDW).[merckmanuals.com] Typical causes of microcytic anemia include: Childhood Iron deficiency anemia, by far the most common cause of anemia in general and of microcytic anemia in particular Thalassemia[en.wikipedia.org] Microcytic anemia is a common category of anemia. Iron deficiency anemia is the most common type of microcytic anemia and is also the most common anemia.[ncbi.nlm.nih.gov]

  • Alpha Thalassemia

    Histologic Findings Peripheral blood smear may reveal target cells, microcytosis, hypochromia, and anisopoikilocytosis.[emedicine.medscape.com] MATERIAL AND METHODS: Two hundred six patients with hypochromic microcytic anemia were evaluated for alpha thalassemia.[ncbi.nlm.nih.gov] Peripheral smear shows target cells, teardrop RBCs, polychromasia, moderate anisopoikilocytosis, and basophilic stippling.[clinicaladvisor.com]

  • Haemoglobin E Disease

    The peripheral blood picture showed severe anisopoikilocytosis of the red blood cells (RBCs) with the presence of a fair number of microcytes, target cells, tear drop cells[jdrntruhs.org] Hb E disease (homozygous Hb E, Hb EE) is also a benign disorder with a mild microcytic anemia (average MCV 62 fl, Hgb 12 g/dl).[path.upmc.edu] In homozygotes, a mild microcytic anemia with prominent target cells exists. Diagnosis of hemoglobin E disorders is by hemoglobin electrophoresis.[merckmanuals.com]

  • Hemoglobin E-Thalassemia

    The peripheral blood picture showed severe anisopoikilocytosis of the red blood cells (RBCs) with the presence of a fair number of microcytes, target cells, tear drop cells[jdrntruhs.org] Hb E disease (homozygous Hb E, Hb EE) is also a benign disorder with a mild microcytic anemia (average MCV 62 fl, Hgb 12 g/dl).[path.upmc.edu] In homozygotes, a mild microcytic anemia with prominent target cells exists. Diagnosis of hemoglobin E disorders is by hemoglobin electrophoresis.[merckmanuals.com]

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