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349 Possible Causes for Ankle Pain, C-Reactive Protein Increased, Hepatomegaly, Serositis, Swollen Knee

  • Juvenile Onset Stills Disease

    You may especially feel the joint pain in your hands, wrists, elbows, shoulders, knees and ankles.[disabilitycasereview.com] Laboratory findings may reveal increased white blood cell count and markers of inflammation such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and fibrinogen[symptoma.com] The initial signs of arthritis, which can be subtle or noticeable, may include walking difficulties, tender wrist, finger, or knee.[dovemed.com] […] days, with at least one of the following manifestations: skin rash (evanescent, non-fixed erythematous rash that accompanies fever spikes), generalized lymphadenopathy, hepatomegaly[stillsdisease.org] […] serum ferritin or C-reactive protein levels. 5 , 7 These findings suggest that elevated serum concentrations of IL-18 would be closely specific for AOSD among systemic inflammatory[nature.com]

  • Adult-Onset Still Disease

    Joint pain - The involvement of knees, wrists, or ankles is another important manifestation of AOSD.[symptoma.com] […] serum ferritin or C-reactive protein levels. 5 , 7 These findings suggest that elevated serum concentrations of IL-18 would be closely specific for AOSD among systemic inflammatory[doi.org] The lymph nodes in your neck might be swollen and tender. Achy and swollen joints. Your joints — especially your knees and wrists — might be stiff, painful and inflamed.[mayoclinic.org] Liver involvement was observed in all cases, with hepatomegaly in 81.3%, increased liver enzymes in 50.0%, and hypergammaglobulinemia in 68.8%.[ncbi.nlm.nih.gov] Other joints in pain include the elbow joints, shoulder joints and ankle joints.[drburkeortho.com]

  • Muckle Wells Syndrome

    Back pain, joint and ankle pain, GI issues, some headaches, plugged ears and ear infections, fatigue are def. daily and some are weekly issues.[rareshare.org] Also, they have increased erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and serum amyloid A (SAA).[symptoma.com] Usually, only one joint is affected at a time, most commonly an ankle or a knee. The joint may be so swollen and painful that the child cannot walk.[my.clevelandclinic.org] Chest radiograph (x-ray) for infection, inflammatory lung disease or serositis.[clinicaladvisor.com] CASE 2 Female patient, aged 24, with episodes of pain and edema on the ankles, associated with non-pruriginous urticaria, related to the cold, since infancy.[scielo.br]

  • CINCA Syndrome

    These overgrowth arthropathies can cause gross deformity of the joints, with pain and limited range of motion.[printo.it] […] amyloid A and C-reactive protein in the blood and an increase in the erythrocyte sedimentation rate (blood tests used to measure elevations of these markers can detect or[rarediseases.org] The photograph below shows swollen knees in CINCA[pmmonlineindia.org] […] with retinal scarring, corneal haze or vision loss. [6] , [26] Cardiopulmonary: Some may have a pericardial effusion, or pericarditis. [1] Abdominal: Some patients have hepatomegaly[autoinflammatory-search.org] Drug Indication Risks Benefits NSAIDS Arthritis; pain, fever Adverse reactions Reduce fever, pain, arthritis Corticosteroids Fever, arthritis, serositis, urticaria, vasculitis[cancertherapyadvisor.com]

  • Oligoarthritis

    In September she was referred to the rheumatology outpatient department with a three month history of painful swollen ankles, chest pains, and generalised weakness.[pmj.bmj.com] C-reactive protein (CRP) is a protein that the liver releases into the blood at the start of infection or inflammation; this level can rise if a person is having an arthritis[m.kidshealth.org] A limp in the morning and a swollen knee may be the only sign that something is wrong; sometimes a visiting grandmother notices what the parents have overlooked.[mdedge.com] Individuals with systemic arthritis may also have a skin rash or enlargement of the lymph nodes (lymphadenopathy), liver (hepatomegaly), or spleen (splenomegaly).[ghr.nlm.nih.gov] Sometimes the swelling can spread to the internal organs, affecting the heart, liver, spleen, and the tissue that surrounds the organs (serositis).[healthline.com]

  • Polyarticular Juvenile Idiopathic Arthritis

    Affects four or fewer joints, often the knee or ankle. Symptoms include pain, stiffness, or swelling in the joints.[kidshealth.org] Symptoms are swollen, painful joints, particularly the knees and/or ankles. Eye inflammation is common and specialist eye checks are needed.[contact.org.uk] (Still's Disease) High daily Relapsing Fever 39 degrees persists over 2 weeks (most distinguishes this type from others) Polyarticular involvement with 4 joints involved Hepatomegaly[fpnotebook.com] […] limited range of motion tenderness to palpation uveitis visceral involvement in cases of systemic JIA such as evanescent and salmon-colored macular rash hepatosplenomegaly serositis[medbullets.com] Hepatomegaly and/or splenomegaly. Serositis (pericarditis, pleuritis, peritonitis).[patient.info]

  • Enthesitis-Related Arthritis

    The enthesitis is commonly around the kneecaps and the heels, and joints—usually spine, hips, knees, and ankles—are stiff and painful. ERA is more common in boys.[myhealth.alberta.ca] C-reactive protein (CRP) is a protein that the liver releases into the blood at the start of infection or inflammation; this level can rise if a person is having an arthritis[kidshealth.org] The photograph shows polyarthritis of the hands and wrists The photograph below shows swollen knees and quadriceps wasting The photograph below shows swollen small joints[pmmonline.org] Individuals with systemic arthritis may also have a skin rash or enlargement of the lymph nodes (lymphadenopathy), liver (hepatomegaly), or spleen (splenomegaly).Oligoarticular[icdlist.com] The enthesitis is usually around the knee-caps, heels, and joint parts – usually backbone, hips, ankles and knees are painful and stiff.[enthesitis.org]

  • Familial Mediterranean Fever

    FMF flares lasting from a few hours to 3-4 days can involve the following symptoms: [5,7,8] Fever Abdominal and/or chest pain Inflammation of a joint e.g. , knee, ankle, wrist[periodicfevers.com] […] white blood cell count ( leukocytosis ), erythrocyte sedimentation rate ( ESR ), serum fibrinogen , C-reactive protein ( CRP ) Increased serum IgD in 10% X-rays of abdomen[dermnetnz.org] Signs and symptoms of familial Mediterranean fever include: Fever Abdominal pain Chest pain Achy, swollen joints A red rash on your legs, especially below your knees Muscle[mayoclinic.org] At age 6 months she was admitted with pericarditis, followed by further admissions with episodic vomiting, lethargy, poor feeding, diarrhea, and hepatomegaly.[bloodjournal.org] Abstract Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation.[ncbi.nlm.nih.gov]

  • Tuberculosis

    […] paralysis, in as many as half of patients with undiagnosed Pott disease Tuberculous arthritis, usually involving only 1 joint (most often the hip or knee, followed by the ankle[emedicine.medscape.com] Laboratory test revealed increased C-reactive protein level and erythrocyte sedimentation rate.[ncbi.nlm.nih.gov] She also had tender hepatomegaly and free fluid in the abdomen. Her oxygen saturation was 85% on pulse oximetry.[pubmedcentral.nih.gov] Paradoxical TB IRIS is a clinical diagnosis, characterized by new or worsening enlarged lymph nodes, radiographic features of TB, serositis, or CNS manifestations, and often[hivinsite.org] Decreases in erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) ( P 1.24 10 12 ) and an increase in serum albumin concentration ( P 5.17 10 21 ) were also seen[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    […] swelling and fluid accumulation Pain in the chest when breathing deeply ( pleurisy ) A butterfly-shaped rash across the cheeks and nose Hair loss Sensitivity to the sun and[webmd.com] Laboratory test revealed increased C-reactive protein level and erythrocyte sedimentation rate.[ncbi.nlm.nih.gov] Other signs are: Pancreatitis, Lupus Enteropathy, Hepatitis and Hepatomegaly 5. Systemic Fever, Malaise/Fatigue, Lymphadenopathy, Weight loss 6.[fidanoski.ca] ESRp, serositis, and anti-dsDNA antibodies were related to disease activity regardless of infections.[ncbi.nlm.nih.gov] In the general population, increased serum levels of C-reactive protein, intracellular adhesion molecule 1, and CD40 ligand are associated with an increased risk of cardiovascular[dx.doi.org]

    Missing: Swollen Knee

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