Antinuclear Autoantibodies: Causes & Reasons

Possible Causes for Antinuclear Autoantibodies

KEYWORDS: Autoimmune hepatitis; anti smooth muscle antibodies; antinuclear antibodies; autoantibodies; hypergammaglobulinemia; interface hepatitis; liver kidney microsome [ncbi.nlm.nih.gov]

The diagnosis is established by detecting high titers of autoantibodies such as antinuclear antibodies, anti-smooth muscle antibodies, and elevated immunoglobulins. [ncbi.nlm.nih.gov]

Autoantibodies Data regarding autoantibodies at diagnosis, including antinuclear antibody, smooth muscle antibody, liver/kidney microsomal, and LC1 antibodies, are provided [pediatrics.aappublications.org]

Discoid Lupus Erythematosus

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz -- Part I: Introduction [worldcat.org]

Routine laboratory tests were normal, tests for autoantibodies (antinuclear antibody, extractable nuclear antigen, and anti-Ro/ SSA and anti-La/SSB) were negative and immunohistochemistry [scielo.br]

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz --Part I: Introduction. [worldcat.org]

Dermatomyositis

Auto-antibodies A variety of auto-antibodies are associated with the disease and include Antinuclear Autoantibodies (ANA), Rheumatoid Factor (RF), and more specific myositis-associated [pathwaymedicine.org]

Patients frequently have circulating autoantibodies antinuclear antibodies (ANAs) and more specific antibodies may be present (e.g. anti-Mi2, anti-Tiff1gamma, anti-MDA5). [orpha.net]

Primary Biliary Cirrhosis

Patients with PBC have antimitochondrial autoantibodies (AMA) and additionally 50% of them have antinuclear antibodies (ANA). [doi.org]

Although drug-induced liver injury was possible, positive autoantibody tests (antinuclear antibodies >1/1280, anti-mitochondrial M2 antibodies 21 index value) also suggested [ncbi.nlm.nih.gov]

Other autoantibodies (eg, antinuclear antibodies [ANAs], anti–smooth muscle antibodies, rheumatoid factor) may be present. [msdmanuals.com]

Systemic Lupus Erythematosus

Systemic lupus erythematosus is characterised by the presence of antinuclear autoantibodies (ANA). [hungary.pure.elsevier.com]

[…] for antinuclear antibodies. [ncbi.nlm.nih.gov]

Presence of antinuclear antibodies. Certain autoantibodies (anti-dsDNA and anti-Sm) have great specificity for the diagnosis of SLE, but lack sensitivity. [accessmedicine.mhmedical.com]

Sjögren Syndrome

They include antibodies to Ro (SSA autoantibodies—see Systemic Lupus Erythematosus (SLE)) or to nuclear antigens (termed La or SSB autoantibodies), antinuclear antibodies, [msdmanuals.com]

The autoantibodies are Rheumatoid factors and antinuclear antibodies called SS-A (Ro) and SS-B (La). [youtube.com]

Autoantibodies have limited sensitivity and particularly low specificity. [msdmanuals.com]

Polymyositis

Antibody Does Not Indicate Autoantibody Negativity in Myositis: Role of Anticytoplasmic Antibody as a Screening Test for Antisynthetase Syndrome Rohit Aggarwal, Namrata Dhillon [jrheum.org]

Autoantibodies: A positive antinuclear antibody (ANA) finding is common in patients with dermatomyositis. [patient.info]

Diffuse Cutaneous Systemic Scleroderma

Autoantibody Subtype (percentage with subtype and autoantibody) Clinical associations Antinuclear antibody Limited cutaneous and diffuse cutaneous (95 percent [nucleolar [aafp.org]

Serological and genetic classification Different autoantibody profiles are associated with particular clinical features and prognosis, particularly the pattern of antinuclear [dermnetnz.org]

Particularly, the ANA, or the antinuclear antibody test, is positive, but not always. [hss.edu]

Systemic Juvenile Idiopathic Arthritis

The oligoarticular and polyarticular forms of JIA are considered as autoimmune diseases and often present with autoantibodies (antinuclear antibodies or rheumatoid factor) [smw.ch]

Evidence for abnormalities in the humoral immune system include the increased presence of autoantibodies (especially antinuclear antibodies), increased serum immunoglobulins [emedicine.medscape.com]

However, SoJIA is closer to the group of autoinflammatory diseases and the detection of positive autoantibodies is uncommon [16–18]. [smw.ch]

Psoriatic Arthritis

Use this form to apply for continuing Pharmaceutical Benefits Scheme (PBS) subsidised treatment with biological agents for psoriatic arthritis. Psoriatic arthritis - continuing PBS authority application form Biological agents refers to all of the following: adalimumab certolizumab etanercept golimumab infliximab[…] [humanservices.gov.au]

Multiple Sclerosis

Dr. Carla Rossotti (left), a general practitioner, and her health care team leave the home of the their patient, 37-year-old Osvaldo Daniel Martinez. He has the symptoms of a degenerative disease, Rossotti says, but he needs a neurologist's evaluation before he can get proper treatment. Sarah Varney/Kaiser Health[…] [npr.org]

Immune Thrombocytopenic Purpura

Immune thrombocytopenic purpura Other names Idiopathic thrombocytopenic purpura, idiopathic immune thrombocytopenia, primary immune thrombocytopenia, idiopathic thrombocytopenic purpura, primary immune thrombocytopenic purpura, autoimmune thrombocytopenic purpura Petechiae, or small bruise-like markings, may occur[…] [en.wikipedia.org]

Rheumatoid Arteritis

A 76-year-old male with a severely deforming rheumatoid arthritis, eosinophilia, polymyositis, and episcleritis developed a transient tonic pupil. The episcleritis, and a muscle biopsy revealing an occlusive arteritis with eosinophilia, suggest that a wide-spread rheumatoid arteritis caused a reversible ischemic insult to[…] [ncbi.nlm.nih.gov]

Nakajo Syndrome

Studies for autoimmunity and autoantibodies are usually negative, but some patients show increased levels of antinuclear antibodies. [frontiersin.org]

Antiphospholipid Syndrome

Antiphospholipid syndrome is an autoimmune disease that is characterized by the presence of several antiphospholipid autoantibody types. The clinical presentation involves thromboembolic events affecting vessels of all sizes, ultimately predisposing the patient to malignant hypertension and life-threatening vascular[…] [symptoma.com]

Chronic Malaria

Extensive explorations of these conditions often include the search for antinuclear autoantibodies (ANA). [ncbi.nlm.nih.gov]

Coxarthritis

Antinuclear autoantibodies, rheumatoid factor, and HLA B 27 haplotype were negative too. [ncbi.nlm.nih.gov]

Familial Behcet-Like Autoinflammatory Syndrome

Three patients from one family had lupus anticoagulants and other autoantibodies, and 3 other unrelated patients had antinuclear autoantibodies. [altmeyers.org]

Mikulicz Disease

autoantibodies, jaundice, diabetes mellitus, swollen duodenal papilla, diffuse pancreatic swelling, spontaneous remission, and relapse. [ncbi.nlm.nih.gov]

Autoantibodies, such as anti-Ro, anti-La, antinuclear antibodies (ANA) and rheumatoid factor may also be detected in the serum. [symptoma.com]

It may be an autoimmune disorder: antinuclear antibodies and autoantibodies to pancreatic antigens have been found in autoimmune pancreatitis. [dermnetnz.org]

Aortic Angiosarcoma

His medical team suspected an autoimmune vasculitis, although HIV, hepatitis, rapid plasma reagin, antineutrophilic cytoplasmic autoantibody, antinuclear antibody, and complement [pubs.rsna.org]

Wissler-Fanconi Syndrome

| Antinuclear Factor | Anti DNA Antibodies | Antibodies, Anti DNA | Antibody, Antinuclear Autoantibodies directed against various nuclear antigens including DNA, RNA, histones [icd9.chrisendres.com]

Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective [icd9.chrisendres.com]

Anetoderma Type Schweninger-Buzzi

C-reactive protein 6.8 mg/l ( Renal parameters: Cystatin C 1.26 mg/l ( Autoantibodies: Antinuclear antibodies (ANA) 1:640, homogenous pattern with prominent nucleoli (< 1: [cosmeticmedicine-online.com]

Autoantibodies: Antinuclear antibodies (ANA) 1:640, homogenous pattern with prominent nucleoli (< 1:80); double-stranded DNA antibodies 49.4 IU/ml (<25); SSA-antibodies 206 [kosmetischemedizin-online.de]

Autoimmune Disease

Serological testing is commonly used to detect autoantibodies, such as antinuclear antibodies (ANA’s) anti-extractable nuclear antigens (ENA’s) and other autoimmune associated [mblintl.com]

Important laboratory tests are antinuclear antibody tests, autoantibody tests, complete blood cound (CBC), comprehensive metabolic panel, C-reactive protein (CRP), Erythrocyte [symptoma.com]

Tests that may be done to diagnose an autoimmune disorder may include: Antinuclear antibody tests Autoantibody tests CBC Comprehensive metabolic panel C-reactive protein [web.archive.org]

Idiopathic Inflammatory Myopathy

METHODS: HLA-DRB1 and TNF promoter genotypes were determined, and serum antinuclear autoantibodies were identified in 120 adult Japanese patients with IIM [72 with dermatomyositis [ncbi.nlm.nih.gov]

Testing for the presence of antinuclear autoantibodies completes the clinical evaluation; further testing for MSA or MAA depends on the pattern of nuclear fluorescence in [err.ersjournals.com]

Autoantibodies: A positive antinuclear antibody (ANA) finding is common in patients with dermatomyositis. [patient.info]

Subacute Cutaneous Lupus Erythematosus

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz -- Part I: Introduction [worldcat.org]

Subacute cutaneous lupus erythematosus occurs in genetically predisposed individuals, most often in patients with the anti-Ro (SS-A) autoantibody, a positive antinuclear antibody [aocd.org]

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz --Part I: Introduction. [worldcat.org]

Lupus Erythematosus

Presence of antinuclear antibodies. Certain autoantibodies (anti-dsDNA and anti-Sm) have great specificity for the diagnosis of SLE, but lack sensitivity. [accessmedicine.mhmedical.com]

(2) 98% of SLE patients have antinuclear antibodies (ANA) but are non-specific anti-double-stranded DNA (dsDNA) seen in around 70% of cases is highly specific for SLE other [gpnotebook.co.uk]

Autoantibodies called antinuclear antibodies (those that bind to the nucleic acid and protein constituents of cell nuclei) are found in nearly all individuals with systemic [britannica.com]

Scleromalacia

[…] screen (including antinuclear antibodies, anti-DNA antibodies, rheumatoid factor, antineutrophil cytoplasmic antibodies), urinalysis, syphilis serology, serum uric acid and [eyewiki.aao.org]

[…] polyarteritis nodosa should be ruled out. boratory tests include complete blood count (CBC) with differential, erythrocye sedimentation rate (ESR) or C-reactive protein (CRP), serum autoantibody [eyewiki.aao.org]

Paraneoplastic Polyneuropathy

An antinuclear autoantibody, named anti-Hu antibody, has been found in patients with CN (Croft et al., 1967; Anderson et al., 1988). [ispub.com]

Autoantibody assessment: antinuclear antibody, rheumatoid factor, anti-Ro/SS-A, anti-La/SS-B, antibodies to acetylcholine receptor, paraneoplastic antibodies-anti-Hu (type [patient.info]

Antineuronal autoantibodies were found in 2 patients (one anti-Hu, one anti-Yo), antinuclear antibodies were found in 1, while in 1 patient no autoantibodies were detected [jtd.amegroups.com]

Antimalarial Medication

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz -- Part I: Introduction [worldcat.org]

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz --Part I: Introduction. [worldcat.org]

Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz -- Part IV: Treatment and [worldcat.org]

Idiopathic Interstitial Pneumonia

Antinuclear antibody was positive in 34.5% of all subjects, rheumatoid factor in 13.2%, and other specific autoantibodies were positive between 0.7%-6.8% of the cases. [ncbi.nlm.nih.gov]

Antinuclear antibody was positive in 34.5{\%} of all subjects, rheumatoid factor in 13.2{\%}, and other specific autoantibodies were positive between 0.7{\%}-6.8{\%} of the [mayoclinic.pure.elsevier.com]

All patients had either myositis-specific or myositis-associated autoantibody. [ncbi.nlm.nih.gov]