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12 Possible Causes for Antinuclear Autoantibodies, Degeneration of Epidermal Basal Cells, Syphilis

  • Discoid Lupus Erythematosus

    Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz -- Part I: Introduction[worldcat.org] Perioral dermatitis and rosacea Sarcoidosis Lichen planus Lichen planopilaris Dermatomyositis Syphilis (see secondary syphilis ) Porphyria (see erythropoietic protoporphyria[visualdx.com] […] hydropic degeneration of the basal cell layer, thickening of the basement membrane zone, telangiectasia, superficial and deep perivascular and periadnexal lymphocytic inflammatory[scielo.br]

  • Systemic Lupus Erythematosus

    Systemic lupus erythematosus is characterised by the presence of antinuclear autoantibodies (ANA).[hungary.pure.elsevier.com] […] with lupus tested positive for syphilis.[hopkinslupus.org] […] of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with[medical-dictionary.thefreedictionary.com]

  • Lichen Sclerosus

    Autoantibodies 316 Not always reported or sought. Thyroid antimicrosomal, gastric parietal cell, and antinuclear autobodies most common.[cirp.org] […] with hydropic degeneration of basal cell, flattening of rete ridges, pronounced edema, and homogenization of collagen in upper dermis with lymphocytic infiltrate in mid-dermis[ncbi.nlm.nih.gov] Is the transmission via an insect vector (Lyme disease), sexually (venereal syphilis), or through casual person-to-person contact (endemic syphilis and pinta)?[cirp.org]

  • Lupus Erythematosus

    Presence of antinuclear antibodies. Certain autoantibodies (anti-dsDNA and anti-Sm) have great specificity for the diagnosis of SLE, but lack sensitivity.[accessmedicine.mhmedical.com] We subsequently reported structures analogous to iSALT in human secondary syphilis, suggesting that iSALT can also exist in humans.[ncbi.nlm.nih.gov] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Vasculitis

    […] antibodies, anti-DNA, anti-Ro, and anti-La antibodies, cryoglobulins, anticardiolipin, and antineutrophil cytoplasmic autoantibodies (ANCA) (indirect immunofluorescence test[jamanetwork.com] […] vasculitic workup assists in determining the organ systems involved and may include urinalysis, C-reactive protein, urea nitrogen/creatinine, CBC, ANCA and ANA testing, syphilis[arupconsult.com] There is sparse scattered lymphocytic infiltration centred around the basal layer /- vacuolar degeneration of the basal layer.[dermnetnz.org]

  • Cutaneous Lupus Erythematosus

    Wallace ; Antinuclear autoantibodies in cutaneous lupus erythematosus: biochemical and cell biological characterization of Ro/SSA / Anna von Mikecz -- Part I: Introduction[worldcat.org] One might, with reservations, compare such increased interest with that shown in the past toward the varied manifestations of syphilis.[annals.org] […] of basal cells; 4) a predominantly lymphocytic infiltrate along the dermal-epidermal junction, around the fair follicles and eccrine ducts, in an interstitial pattern; 14[scielo.br]

  • Actinic Lichen Planus

    Autoantibodies 316 Not always reported or sought. Thyroid antimicrosomal, gastric parietal cell, and antinuclear autobodies most common.[cirp.org] […] reaction frequently are absent (Table 2). 2-4 Differential diagnosis of lichen planus actinicus includes discoid lupus erythematosus, granuloma annulare, melasma, secondary syphilis[mdedge.com] Histology classically demonstrates hyperkeratosis, epidermal thinning, vacuolar degeneration of the basal cell layer, lymphohistiocytic band-like infiltrate, variable Civatte[jcadonline.com]

  • Chilblain Lupus Erythematosus

    Patients with SLE can have a wide variety of autoantibodies against nuclear and cytoplasmic cellular components.[medical-dictionary.thefreedictionary.com] Benign appendageal tumors Plaques Psoriasis Lichen planus Nummular eczema Discoid lupus erythematosus Granuloma annulare Cutaneous T-cell lymphoma Kaposi's sarcoma Secondary syphilis[aafp.org] In particular, skin histopathology of DLE shows classical features: vacuolar degeneration of basal cell layer; thickened basement membrane; orthokeratosis with follicular[ped-rheum.biomedcentral.com]

  • Dyschromatosis symmetrica hereditaria

    Recommended laboratory tests include a complete blood count; sedimentation rate; comprehensive metabolic panel, including liver function tests; and autoantibody tests (antinuclear[what-when-how.com] […] calcium, phosphorus, magnesium, serum lactate, thyroid and parathyroid function, hepatic function, and serum ceruloplasmin level, TORCH screening [Toxoplasmosis, Other (syphilis[ijdvl.com] Light microscopy and ultrastructural studies have also revealed vac-uolar degeneration of basal and parabasal keratinocytes and revealed epidermal and dermal lymphohistiocytic[what-when-how.com]

  • Reticulate Acropigmentation of Kitamura

    Recommended laboratory tests include a complete blood count; sedimentation rate; comprehensive metabolic panel, including liver function tests; and autoantibody tests (antinuclear[what-when-how.com] Arch Dermatol Syphilis 1924;147:389–393. Kitamura K, Akamatsu S, Hirokawa K: Eine besondere Form der Akropigmentation: Acropigmentatio reticularis.[karger.com] Archiv fUr Dermatologie und Syphilis,147, 389.RYCBOFT, R.J.G. (1975) Dermatopathia pigmentosa reticularis.[documents.tips]

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