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396 Possible Causes for Antiphospholipid Syndrome, Easy Bruising

  • Adrenal Insufficiency

    Signs of over-replacement include raised blood pressure, thin skin, striae, easy bruising, glucose intolerance, hyperglycaemia and electrolyte abnormalities.[] ), coagulation disorders, antiphospholipid syndrome , trauma 5 systemic fungal infection: histoplasmosis (most common in the southeastern and south-central United States[] […] or antiphospholipid syndrome ), particular infections ( tuberculosis , histoplasmosis , coccidioidomycosis ), or the deposition of abnormal protein in amyloidosis . [22][]

  • Immune Thrombocytopenic Purpura

    An 11-year-old boy presented with epistaxis, petechial hemorrhages, easy bruising, and purpuric rash.[] Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antibodies directed against phospholipid-binding proteins such as beta-2 glycoprotein[] bruising, nosebleed or bleeding in the mouth.[]

  • Systemic Lupus Erythematosus

    Sometimes changes in blood counts may contribute to symptoms of fatigue (low red blood cell count, anemia), serious infections (low white blood cell count), or easy bruising[] Secondary antiphospholipid syndrome increases the frequency and severity of cardiac valvular disease in systemic lupus erythematosus.[] Continued Sometimes, changes in blood counts (low red cell count, or anemia ), may cause fatigue , serious infections (low white cell count), or easy bruising or bleeding[]

  • Disseminated Intravascular Coagulation

    Other symptoms are: blood clots decreased blood pressure easy bruising rectal or vaginal bleeding red dots on the surface of the skin ( petechiae ) If you have cancer, DIC[] Some connective tissue disorders including antiphospholipid syndrome. [ 2 ] Complications of pregnancy including the placental problem of placental abruption , amniotic fluid[] Work-up for autoimmune disorders including antiphospholipid syndrome was negative. Heparin–platelet complex antibodies were negative.[]

  • Anticardiolipin Antibody Syndrome

    This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome[] Do you have problems with easy bruising or bleeding, or have you noticed small red spots on your skin (petechiae)? Screening for thrombocytopenia required.[] Levine JS et al: The antiphospholipid syndrome. N Engl J Med 2002;346:752. Tincani A et al: Treatment of pregnant patients with antiphospholipid syndrome.[]

  • Hypoprothrombinemia

    bruising, postoperative bleeding, epistaxis, menorrhagia, miscarriage, postpartum hemorrhage, hemarthroses and intracranial bleeding (if severe deficiency) Laboratory Prolonged[] However, bleeding due to lupus anticoagulant-hypoprothrombinemia syndrome is a rare but well-described manifestation of antiphospholipid syndrome.[] […] from antiphospholipid syndrome in that it may cause predisposition not only to thrombosis but also to severe bleeding.[]

  • Purpura Fulminans

    There is evidence of bleeding under the skin, with easy bruising and the development of petechiae.[] This is the first pediatric case of purpura fulminans due to secondary antiphospholipid syndrome of systemic lupus erythematosus.[] Antiphospholipid antibody syndrome can present in catastrophic form, often triggered by infection.[]

  • Primary Biliary Cirrhosis

    Patients may have a low platelet count because of an enlarged spleen causing easy bruising.[] Upon further investigation the patient was diagnosed with autoimmune thyroiditis and antiphospholipid syndrome.[] Cirrhosis can lead to easy bruising, nosebleeds, gallstones, intense itching, kidney failure and liver cancer. It is most commonly caused by alcoholism and hepatitis.[]

  • Factor VII Deficiency

    The symptoms listed in order of frequency were as follows: epistaxis, petechia or ecchymose, easy bruising, and oral cavity bleeding.[] syndrome are frequently associated with these particular thrombotic events, (iii) in the same way, R304Q and A294V FVII variants appear to be more prevalent than other FVII[] Uncontrolled bleeding during menstruation, during and after surgery as well as easy bruising also occur.[]

  • Henoch-Schönlein Purpura

    […] susceptibility Bruise easily Easy bruisability Easy bruising Last updated: 4/14/2013 Unfortunately, there is no cure for Henoch-Schonlein purpura (HSP).[] We report a case of a 65-year-old man with systemic lupus erythematosus (SLE) and antiphospholipid syndrome, presenting palpable purpuric lesions, necrotic blisters and swelling[] . : Primary antiphospholipid syndrome presenting as complicated Henoch-Schönlein purpura . Arch Dis Child 2002, 86 :132–133.[]

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