Antithrombin III Deficiency: Causes & Reasons

Possible Causes for Antithrombin III Deficiency

Congenital Disorder of Glycosylation Type 1J

Patients may be at increased risk of thrombosis due to decreased serum coagulation factors including factors IV, IX, and XI, antithrombin III, protein C, and protein S (29 [ncbi.nlm.nih.gov]

III, protein C, protein S deficiency), hypogammopathy Hyperechoic kidneys, cysts, proteinuria Thyroid abnormalities, IGF1 deficiency, hypogonadotropic hypogonadism, hyperinsulemic [ncbi.nlm.nih.gov]

MPI-CDG (CDG-Ib, mannosephosphate isomerase deficiency) MPI-CDG is unique because affected patients have little to no neurologic involvement and some manifestations of the [ncbi.nlm.nih.gov]

Cerebral Thrombosis

Anticoagulant therapy did not affect the pattern of AT-III on CIE. This family represents a quantitative deficiency in antithrombin III. [ncbi.nlm.nih.gov]

An Israeli Arab family with type I antithrombin III (AT-III) deficiency with several affected symptomatic members in three generations is reported. [ncbi.nlm.nih.gov]

III deficiencies; Factor V Leiden and prothrombin mutations) Acquired (Antiphospholipid antibody, Nephrotic syndrome, Hyperhomocysteinemia, Cyanotic congenital heart disease [eyewiki.aao.org]

Mesenteric Vein Thrombosis

Eleven patients with MVT were screened for protein C, protein S, and antithrombin III deficiencies. Gene analysis was performed by polymerase chain reaction. [ncbi.nlm.nih.gov]

[…] protein S deficiency antithrombin III deficiency recent abdominal surgery intra-abdominal or systemic sepsis portal hypertension mechanical narrowing due to adjacent malignancy [radiopaedia.org]

Protein S, protein C, and antithrombin III deficiencies were present in 1, 1, and 2 patients, respectively. Four patients (36.3%) had combined defects. [ncbi.nlm.nih.gov]

Superior Mesenteric Vein Thrombosis

protein S deficiency, and antithrombin III deficiency) or due to any inflammatory causes (appendicitis, diverticulitis, cholecystitis, pancreatitis, and pelvic inflammatory [surgeryijss.com]

As hematological hypercoagulable states, protein C, protein S or antithrombin III deficiency and antiphospholipid antibody syndrome are well known. [ispub.com]

Intracranial Sinus Thrombosis

III deficiencies; Factor V Leiden and prothrombin mutations) Acquired (Antiphospholipid antibody, Nephrotic syndrome, Hyperhomocysteinemia, Cyanotic congenital heart disease [eyewiki.aao.org]

III - deficiency, plasminogen deficiency, hyperhomocysteinemia, dysfibrinogenaemia, disseminated intravascular coagulation, heparin-induced thrombocytopenia II malignancy [flexikon.doccheck.com]

Muramatsu S, Mizuno Y, Murayama H, Ikemoto S: Hereditary antithrombin III deficiency with a superior sagittal sinus thrombosis: Evidence for a possible mutation starting in [anesthesiology.pubs.asahq.org]

Recurrent Thrombophlebitis due to Hereditary Disorders

Thaler E, Lechner K (1981) Antithrombin-III deficiency and thromboembolism. Clin Haematol 10: 369–390 Google Scholar 7. [link.springer.com]

Antithrombin III deficiency occurs in one of 2000 to 5000 persons. [rnceus.com]

Antithrombin III deficiency: Rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism. [hihg.med.miami.edu]

Cerebral Venous Sinus Disorder

Procoagulant states - polycythemia, prothrombin gene mutation, antiphospholipid antibody syndrome, sickle cell disease, protein S and C deficiencies, antithrombin III deficiency [drrahulchakor.com]

III deficiencies; Factor V Leiden and prothrombin mutations) Acquired (Antiphospholipid antibody, Nephrotic syndrome, Hyperhomocysteinemia, Cyanotic congenital heart disease [eyewiki.aao.org]

antithrombin III deficiency, lupus anticoagulant, or factor V Leiden mutation Cancer Collagen vascular diseases like lupus, granulomatosis with polyangiitis, and Behcet [hopkinsmedicine.org]

Protein S Deficiency

[…] acquired antithrombin III deficiency Thrombophilia due to acquired protein C deficiency Thrombophilia due to acquired protein S deficiency Thrombophilia due to antiphospholipid [icd9data.com]

Information about thrombophilia is widely available on the Internet but it tends to focus on the more common risk factors such as Factor V Leiden, Antithrombin III Deficiency [proteinsdeficiency.com]

3 deficiency Antithrombin III deficiency Factor 5 Leiden mutation Factor 5 Leiden mutation, heterozygous Factor 5 Leiden mutation, homozygous Factor V Leiden mutation Factor [icd9data.com]

Congenital Alpha-2-Antiplasmin Deficiency

Thaler E, Lechner K (1981) Antithrombin III deficiency and thromboembolism. Clin Haematol 10:369–390 PubMed Google Scholar 4. [link.springer.com]

Gomerulopathy with fibronectin deposits Antithrombin III Inhibits IIa, Xa, and other proteases Antithrombin III deficiency Protein C Inactivates Va and VIIIa Protein C Deficiency [doctorshangout.com]

[…] excess without bleeding Anticoagulant-induced bleeding Antithrombin III deficiency Bite of unidentified snake with coagulopathy Bleeds easily Bleeds profusely Blood coagulation [emedcodes.com]

Cerebral Vein Thrombosis

We report a patient with fatal cerebral vein thrombosis following myelography, in whom the cause was familial antithrombin III (AT3) deficiency. [ncbi.nlm.nih.gov]

antithrombin III deficiency, lupus anticoagulant, or factor V Leiden mutation Cancer Collagen vascular diseases like lupus, Wegener’s granulomatosis, and Behcet syndrome [hopkinsmedicine.org]

antithrombin III deficiency, lupus anticoagulant, or factor V Leiden mutation Cancer Collagen vascular diseases such as lupus, granulomatosis with polyangiitis, and Behcet [cedars-sinai.edu]

Sagittal Sinus Thrombosis

Other factors include: Primary haematological disorders antiphospholipid syndrome thrombophilia (protein S deficiency, resistance to activated protein C and antithrombin III [mrcophth.com]

The etiology of CVT is diverse but most often includes the following: ● Genetic hypercoagulable states (e.g., protein S and C deficiencies, antithrombin III deficiency, Leiden [casemed.case.edu]

III deficiencies; Factor V Leiden and prothrombin mutations) Acquired (Antiphospholipid antibody, Nephrotic syndrome, Hyperhomocysteinemia, Cyanotic congenital heart disease [eyewiki.aao.org]

Hereditary Antithrombin Deficiency Type 2

Pulmonary thromboembolectomy in congenital antithrombin III deficiency associated with acute pulmonary embolism: report of a case. [ekjm.org]

By contrast, hereditary deficiency of antithrombin III type 1 is associated with quantitative deficiencies of antithrombin III. [symptoma.com]

[cze0080837] deficience antitrombinu III [cze0080838] vrozený deficit antitrombinu III [cze0080839] See Deficiency, Antithrombin III [T059945] Antithrombin 3 Deficiency [ [medvik.cz]

Hereditary Antithrombin Deficiency

A family study spanning four generations revealed a total of 10 members with antithrombin III deficiency. [ncbi.nlm.nih.gov]

Deficiencies, Deficiencies, Antithrombin III, Deficiency, Antithrombin III, AT-III deficiency, antithrombin III deficiency, antithrombin III deficiency (diagnosis), Antithombin [fpnotebook.com]

Antithrombin III deficiency Other names ATIII deficiency Specialty Hematology Antithrombin III deficiency (abbreviated ATIII deficiency) is a deficiency of antithrombin III [en.wikipedia.org]

Hereditary Protein C Deficiency

Antithrombin (AT) III deficiency (now simply called antithrombin deficiency ) refers to a congenital lack of the endogenous anticoagulant antithrombin. [radiopaedia.org]

Antithrombin III deficiency and the antiphospholipid syndrome may also be associated with livedo reticularis, and we suggest that a thrombophilia screen may be a useful investigation [ncbi.nlm.nih.gov]

Antithrombin Deficiency

(Also known as/Synonyms) AT 3 Deficiency AT III Deficiency Hereditary Thrombophilia due to Antithrombin III Deficiency What is Antithrombin III Deficiency? [dovemed.com]

Antithrombin III deficiency (abbreviated ATIII deficiency ) is a deficiency of antithrombin III. [en.wikipedia.org]

In the United States, Antithrombin III deficiency occurs 1 in 1000 people 2 Causes of Antithrombin III Deficiency Antithrombin III is just a kind of protein in your blood. [inrtracker.com]

Thrombophilia due to Activated-Protein C Resistance

3 deficiency, antithrombin III deficiency, factor 5 Leiden mutation, factor 5 Leiden mutation heterozygous, factor 5 Leiden mutation homozygous, factor V Leiden mutation, [healthresearchfunding.org]

3 deficiency Antithrombin III deficiency Factor 5 Leiden mutation Factor 5 Leiden mutation, heterozygous Factor 5 Leiden mutation, homozygous Factor V Leiden mutation Factor [icd9data.com]

Factor II Mutation

antithrombine III deficiency or antiphospholipid syndrome are permanent factors. [scielo.isciii.es]

The same could be said for antithrombin III, protein C and protein S deficiencies. [my.clevelandclinic.org]

Other inherited thrombophilias include protein C deficiency, protein S deficiency, and antithrombin III deficiency. [cleveland.com]

Hereditary Coagulopathy

Anticoagulant-induced bleeding Anti-factor II disorder Antithrombin III deficiency Bite of unidentified snake with coagulopathy Bleeds easily Bleeds profusely Blood coagulation [icd9data.com]

deficiency α1-antitrypsin Pittsburgh (Antithrombin III Pittsburgh) deficiency ( Haematologica 2009;94:881 ) Combined factor deficiencies: combined factor V and VIII (autosomal [pathologyoutlines.com]

Hereditary Factor I Deficiency

III deficiency Hypercoagulable state NOS Primary hypercoagulable state NEC Primary thrombophilia NEC Protein C deficiency Protein S deficiency Thrombophilia NOS D68.6 Other [icd10coded.com]

Matsui, W. (2002 February 2, Updated).Congenital antithrombin III deficiency. MedlinePlus Health Information, Medical Encyclopedia [On-line information]. [labtestsonline.it]

Abdominal Aortic Thrombosis

Kauffmann RH, Veltkamp JJ, Van Tilburg NH, Van Es LA: Acquired antithrombin III deficiency and thrombosis in the nephrotic syndrome. Am J Med 1978;65:607–613. [karger.com]

III deficiency), and systemic fungal infections.[7] Generally, thromboembolic events are associated with advanced age with the thrombus arising from complex and ulcerated [medscape.com]

Acute arterial thrombosis with antithrombin III deficiency in nephrotic syndrome: Report of a case. Surg Today 2000; 30:663-6. 6. [sjkdt.org]

Protein C Deficiency

Congenital antithrombin III deficiency. MedlinePlus Medical Encyclopedia [On-line information]. [labtestsonline.org.tr]

Antithrombin III Deficiency. eMedicine. Available online through http://www.emedicine.com. Accessed on 3/9/08. Dugdale, D. (Updated 2012 June 5). Antithrombin III. [labtestsonline.org]

Hereditary Thrombophilia due to Congenital Protein S Deficiency

NOS ( E63.9 ) C D68.59 S D68.59 antithrombin D68.59 (antithrombin III) Hypercoagulable (state) D68.59 antithrombin D68.59 (III) primary NEC D68.59 protein C deficiency D68.59 [icd10data.com]

Plasma Levels of Antithrombin III, Protein C, Protein S, and Plasminogen in the Patients with Venous Thromboembolism and Protein Deficiencies.* An isolated deficiency of antithrombin [nejm.org]

There were 17 cases of protein C deficiency (PC), 15 protein S deficiency (PS), 10 antithrombin III deficiency (ATIII), 3 dyfibrinogenemia, 2 heparin cofactor II deficiency [cags.org.ae]

Budd-Chiari Syndrome

Antithrombin III deficiency was detected in 14 (58.3%) of those tested patients. Anticoagulants were used in 24 (53.3%) patients. TIPS was done in 11 (24.4%) patients. [ncbi.nlm.nih.gov]

Antithrombin III deficiency Inflammatory bowel disease Behçet syndrome Vena caval webs: more common in Asians Idiopathic membranous stenosis of inferior vena cava (IVC) Compression [unboundmedicine.com]

Clots commonly result from the following: Thrombotic conditions (eg, protein C or S deficiency, antiphospholipid syndrome, antithrombin III deficiency, factor V Leiden mutation [merckmanuals.com]

Venous Thrombosis

Other inherited causes include protein C, protein S, or antithrombin III deficiencies. [occhioclinico.it]

Postoperative investigation disclosed combined deficiency of antithrombin III and protein C. His son also showed deficiency of antithrombin III. [kci.go.kr]

Anticoagulant-induced bleeding Anti-factor II disorder Antithrombin III deficiency Bite of unidentified snake with coagulopathy Bleeds easily Bleeds profusely Blood coagulation [icd9data.com]

Renal Vein Thrombosis

[…] stats  Protein C deficiency  Protein S deficiency  Antithrombin deficiency  Factor V leiden  Disseminated malignancy 7. d/t hemostatic abnormalities Decreased level [slideshare.net]

Other causes include Diabetic nephropathy Estrogen therapy Pregnancy Primary hypercoagulability disorders (eg, antithrombin III deficiency, protein C or S deficiency, factor [merckmanuals.com]

Kauffmann RH, Veltkamp JJ, Van Tilburg NH, Van Es L: Acquired antithrombin III deficiency and thrombosis in the nephrotic syndrome. [link.springer.com]

Ischemic Bowel Disease

antithrombin III deficiency - oral contraceptive - pregnancy - polycythaemia vera - thrombocytosis Inflammation - pancreatitis - peritonitis - inflammatory bowel disease [aic.cuhk.edu.hk]

Venous thrombosis• Hypercoagulable states induced, for example, by oral contraceptive or antithrombin III deficiency,• intraperitoneal sepsis,• the postoperative state,• vascular [slideshare.net]

Knot E, Ten Cate J, Bruin T, Iburg A, Tytgat G: Antithrombin III metabolism in two colitis patients with acquired antithrombin III deficiency. [karger.com]

Superficial Phlebitis

Pregnancy and the early postpartum period as well as thrombophilic states (e.g., antithrombin III deficiency and factor V Leiden deficiency) also predispose patients to the [journals.lww.com]

Systemic lupus erythematosus Acquired immunodeficiency syndrome (AIDS) - Lupus anticoagulant Drug-induced lupus anticoagulant Antithrombin III deficiency Behçet disease [emedicine.medscape.com]

III (AT-III) deficiency protein C deficiency protein S deficiency Your doctor will examine the affected area and the skin. [healthline.com]

Idiopathic Recurrent and Disabling Cutaneous Herpes

Other risk factors for developing leg ulceration are anemia, male sex, combined HLA-B35 and HLA-Cw4, and antithrombin III deficiency. [emedicine.medscape.com]

Thrombomodulin-Related Bleeding Disorder

Matsui, W. (2002 February 2, Updated).Congenital antithrombin III deficiency. MedlinePlus Health Information, Medical Encyclopedia [On-line information]. [labtestsonline.it]

Pregnancy in women with congenital antithrombin III deficiency: experience of treatment with heparin and antithrombin. Gynecol Obstet Invest. 1982. 14(2):127-41. [emedicine.medscape.com]

The hereditary deficiency of antithrombin III is associated with an excessive tendency toward clot formation, and manifestations of this defect are recurrent thrombophlebitis [britannica.com]

Hypoplasminogenemia

The ICD code D688 is used to code Antithrombin III deficiency Antithrombin III deficiency (abbreviated ATIII deficiency) is a deficiency of antithrombin III. [icd.codes]

The first thrombotic inhibitor defect recognized was antithrombin III deficiency which was reported in 1965. [link.springer.com]

Matsui, W. (2002 February 2, Updated).Congenital antithrombin III deficiency. MedlinePlus Health Information, Medical Encyclopedia [On-line information]. [labtestsonline.it]