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12 Possible Causes for Anxiety, Cognitive Developmental Delay, Wide Space Between the First and Second Toe

  • Down Syndrome

    Preparing them for what will happen can reduce anxiety and illustrate socially appropriate behavior.[chw.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] […] variants: or Down's syndrome Definition of Down syndrome : a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in[merriam-webster.com]

  • Seckel Syndrome

    Tay-Sachs テイ・サックス Tay-Sachs disease テイ・サックス病 Warren Tay(1843- 1927) British ophthalmologist and Bernard Sachs(1858 - 1944) American neurologist Taylor テーラー Taylor manifest anxiety[jams.med.or.jp] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Dubowitz Syndrome

    In brief, Patient 1 is a 41-year-old male with metabolic syndrome, panic attacks and anxiety, primary hypogonadism, learning disabilities, and dysmorphic features.[journals.plos.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The feeding difficulties, developmental and cognitive delay, mottled skin, drug-induced long QT syndrome, short stature, microcephaly, small ears, 2–3 cutaneous syndactyly[journals.plos.org]

  • Macrocephaly-Developmental Delay Syndrome

    Since the early 2000s, PTEN germline mutation haploinsufficiency has been reported in association with autism, variable cognitive impairment and developmental delay in the[consultqd.clevelandclinic.org] The most common DSM-IV diagnosis among the Fragile X boys is ADHD (73%), followed by oppositional defiant disorder, anxiety disorders (Baumgardner et al., 1995).[intellectualdisability.info] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Russell-Silver Syndrome

    The patient was initiated on Hydroxyzine 50 mg PO every 6 hours PRN for her anxiety, Acetaminophen 650 mg PO every 6 hours PRN and Quetiapine 50 mg PO at night.[omicsonline.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Children with RSS have an increased risk for developmental delay (both motor and cognitive) and learning disabilities.[gemssforschools.org]

  • Cutis Laxa

    Beighton et al . [15] advocated plastic surgical intervention at an early age in patients with congenital cutis laxa to avoid social anxiety in school-going children and the[e-ijd.org] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] Despite delays in developmental milestones and language, affected children are said to be cheerful and outgoing. Neurologic findings Cognitive.[ncbi.nlm.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Developmental delays are common. Infancy and childhood milestones are often delayed. Many patients have cognitive delays and some are mildly retarded.[disorders.eyes.arizona.edu] (9) Anxiety disorders (2) Attention-deficit/hyperactivity disorder (10) Behavior disorders (2) Bipolar disorder (8) Bulimia nervosa (4) Cognitive-bahvioral therapy (1) Combat[innovations.ahrq.gov] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Genee-Wiedemann Syndrome

    […] dysgenesis; 107250; PITX3 Antithrombin III deficiency; 613118; AT3 Antley-Bixler syndrome; 207410; FGFR2 Antley-Bixler syndrome-like with disordered steroidogenesis; 201750; POR Anxiety-related[howlingpixel.com] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] Estimates have been made for individuals with specific clinical presentations such as developmental delay/cognitive disability and autism spectrum disorders; in these phenotypes[nature.com]

  • Trisomy 10p

    Thanksgiving will relieve the anxiety, the stress, and the depression in your life.[notearsinheaven.com] spaced, inverted nipples, mild pectus excavatum; and a sandal gap between the first and second toes.[jmg.bmj.com] The last physical examinationwas at 12months of age and a global developmental delay was established.[docslide.fr]

  • Mild Dysmorphic Features

    Body dysmorphia isn't a simple extension of low self-esteem, or bad body image; it's a much-misunderstood anxiety disorder with strong links to obsessive-compulsive traits[bustle.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com] […] impairment No Ring chromosome 4 Mental developmental delay, deafness, short stature, obesity and the onset of type 2 diabetes in adolescence No Ring chromosome 11 Ocular[raredr.com]

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