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14 Possible Causes for Anxiety, Macroglossia, Wide Space Between the First and Second Toe

  • Down Syndrome

    Preparing them for what will happen can reduce anxiety and illustrate socially appropriate behavior.[chw.org] Dental malocclusion and macroglossia are associated. Technical modifications to increase macroglossia surgery safety and efficacy have been described.[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Multiple Endocrine Neoplasia Type 2B

    Pheochromocytoma can present as sustained or episodic hypertension, along with episodic headache, diaphoresis, palpitations, tachycardia, and anxiety.[clinicaladvisor.com] Between ages 2 and 4, they develop full lips, large rounded cheeks , a broad nose , and an enlarged tongue ( macroglossia ).[ghr.nlm.nih.gov] Figure 3 The first toe is longer than the others and there is a wide space between the first and second toe.[ijponline.biomedcentral.com]

  • Genee-Wiedemann Syndrome

    […] dysgenesis; 107250; PITX3 Antithrombin III deficiency; 613118; AT3 Antley-Bixler syndrome; 207410; FGFR2 Antley-Bixler syndrome-like with disordered steroidogenesis; 201750; POR Anxiety-related[howlingpixel.com] […] repair in neonates, endotracheal intubation for insufficient airway, and use of specialized nipples or nasogastric tube feedings to manage feeding difficulties resulting from macroglossia[checkorphan.org] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com]

  • Dubowitz Syndrome

    In brief, Patient 1 is a 41-year-old male with metabolic syndrome, panic attacks and anxiety, primary hypogonadism, learning disabilities, and dysmorphic features.[journals.plos.org] […] lipodystrophy Congenital muscular dystrophy type 1A Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation Dextrocardia Peters plus syndrome Macroglossia[checkrare.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Weaver Syndrome

    Learning disabilities Frequent upper respiratory infections Behavioral disturbance (anxiety, depression, phobias, sleep disturbance, tantrums, irritability, stereotypies,[sotossyndrome.org] Macroglossia and hypothyroidism are seldom mentioned in the literature as clinical findings associated with the syndrome.[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Russell-Silver Syndrome

    The patient was initiated on Hydroxyzine 50 mg PO every 6 hours PRN for her anxiety, Acetaminophen 650 mg PO every 6 hours PRN and Quetiapine 50 mg PO at night.[omicsonline.org] Physical findings are variable and can include abdominal wall defects, macroglossia, and hemihyperplasia.[mayomedicallaboratories.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Cutis Laxa

    Beighton et al . [15] advocated plastic surgical intervention at an early age in patients with congenital cutis laxa to avoid social anxiety in school-going children and the[e-ijd.org] The facies are coarse with thick lips, macroglossia and relative macrocephaly.[caribbean.scielo.org] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br]

  • Familial Congenital Nasolacrimal Duct Obstruction

    (9) Anxiety disorders (2) Attention-deficit/hyperactivity disorder (10) Behavior disorders (2) Bipolar disorder (8) Bulimia nervosa (4) Cognitive-bahvioral therapy (1) Combat[innovations.ahrq.gov] Macroglossia is associated with several systemic conditions.[quizlet.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Seckel Syndrome

    Tay-Sachs テイ・サックス Tay-Sachs disease テイ・サックス病 Warren Tay(1843- 1927) British ophthalmologist and Bernard Sachs(1858 - 1944) American neurologist Taylor テーラー Taylor manifest anxiety[jams.med.or.jp] […] familial 池田 康行 110 61 lissencephaly syndrome 泉川 良範 115 62 Lujan-Fryns syndrome 泉川 良範 117 63 lung 泉川 良範 118 64 lymphedema 泉川 良範 121 65 Machado-Joseph disease 斉藤 伸治 122 66 macroglossia[nippon-rinsho.co.jp] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Trisomy 10p

    Thanksgiving will relieve the anxiety, the stress, and the depression in your life.[notearsinheaven.com] There may be a large tongue (macroglossia). There may be flattening of the cheek area (midface hyperplasia). Individuals are noted to have a short neck.[rarediseases.org] spaced, inverted nipples, mild pectus excavatum; and a sandal gap between the first and second toes.[jmg.bmj.com]

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