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22 Possible Causes for Anxiety, Small Face, Wide Space Between the First and Second Toe

  • Down Syndrome

    Preparing them for what will happen can reduce anxiety and illustrate socially appropriate behavior.[chw.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Morphological features (upslanting palpebral fissures, epicanthus, flat neck, round face, small nose, bilateral single palmar crease) can be mild and do not constitute a hallmark[orpha.net]

  • Dubowitz Syndrome

    In brief, Patient 1 is a 41-year-old male with metabolic syndrome, panic attacks and anxiety, primary hypogonadism, learning disabilities, and dysmorphic features.[journals.plos.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] For example, many people affected by the disease have a small face and head. Sometimes they have a high forehead that slopes as well.[wisegeek.net]

  • Russell-Silver Syndrome

    The patient was initiated on Hydroxyzine 50 mg PO every 6 hours PRN for her anxiety, Acetaminophen 650 mg PO every 6 hours PRN and Quetiapine 50 mg PO at night.[omicsonline.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The wide prominent forehead contrasts with the small, triangular face with a small pointed chin, a wide mouth with thin lips and down-turned corners, large eyes and bluish[orpha.net]

  • Ring Chromosome 10

    Questionnaire has been selected to cover important dimensional aspects of mental illness such as Behaviour and Cognition (Psychosis, Depression, Anxiety, Impulsiveness, Aggression[re3data.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] In addition, the syndrome causes a prognathism, the face is long and small and the patient has large ears.[embryology.ch]

  • Kleiner Holmes Syndrome

    J Anxiety Disord 21: 510-525.[omicsonline.org] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] ; High, flat forehead; Low frontal hairline; Maxillary hypoplasia; Facial asymmetry; Long and prominent ear crus; Small ears; Low-set ears; Apical cartilage deformity; Deafness[panelapp.genomicsengland.co.uk]

  • Seckel Syndrome

    Tay-Sachs テイ・サックス Tay-Sachs disease テイ・サックス病 Warren Tay(1843- 1927) British ophthalmologist and Bernard Sachs(1858 - 1944) American neurologist Taylor テーラー Taylor manifest anxiety[jams.med.or.jp] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] General appearance of the patient was characterized by a small, narrow face and forehead, slightly beaked nose, midfacial hypoplasia, very stunted stature with microcephaly[termedia.pl]

  • Short Stature due to Endocrine Disorder

    […] of nose Widened nasal bridge [ more ] 0000431 Percent of people who have these symptoms is not available through HPO Abnormality of the rib cage 0001547 Agitation 0000713 Anxiety[rarediseases.info.nih.gov] [from OMIM ] Anxiety MedGen UID: 1613 • Concept ID: C0003467 • Finding Apprehension of danger and dread accompanied by restlessness, tension, tachycardia, and dyspnea unattached[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Cutis Laxa

    Beighton et al . [15] advocated plastic surgical intervention at an early age in patients with congenital cutis laxa to avoid social anxiety in school-going children and the[e-ijd.org] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] […] forehead, triangular-shaped face, and large ears.[cutislaxa.pitt.edu]

  • Kenny-Caffey Syndrome Type 1

    Nervous system disorders and psychiatric disorders Other clinical features include: Clumsiness Tremors Difficulty walking Speech problems Impaired thinking ability Depression Anxiety[wikidoc.org] space between the first and second toes.[medcraveonline.com] , and frontal bossing with a triangular face.[uniprot.org]

  • Familial Congenital Nasolacrimal Duct Obstruction

    (9) Anxiety disorders (2) Attention-deficit/hyperactivity disorder (10) Behavior disorders (2) Bipolar disorder (8) Bulimia nervosa (4) Cognitive-bahvioral therapy (1) Combat[innovations.ahrq.gov] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] The face is often broad and round, the nose is beaked, the mouth is small, and the lower lip appears to pout and protrudes beyond a short upper lip.[disorders.eyes.arizona.edu]

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