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10 Possible Causes for Aortic Valve Insufficiency, Bilateral Leg Weakness

  • Hereditary ATTR Amyloidosis

    What is TTR-FAP and who gets it? Approximately 10,000, or 1.1 per 100,000 people in the world, are estimated to be living with TTR-FAP, which often shows up when patients are in their thirties or forties. TTR-CM tends to affect older males, ie., men who are 65 or older. However, many cases of both forms of the[…][pfizer.com]

  • Paraparesis

    PARAPARESIS Paraparesis refers to bilateral leg weakness.[pediatricneuro.com] If it affects the ascending aorta, it may cause cardiac complications such as myocardial infarction, aortic valve insufficiency, or cardiac tamponade.[ahajournals.org] leg weakness Applies To Paralysis of both lower limbs Paraplegia (lower) ICD-9-CM Volume 2 Index entries containing back-references to 344.1 :[icd9data.com]

  • Syncope

    The isoproterenol tilt testing is contraindicated in patients with ischemic heart disease. 2 Limitations to the head-up tilt test include: inability to stand (leg weakness[clevelandclinicmeded.com] […] or pain, severe back pain), unstable medical conditions, inability to obtain blood pressure (incompressible arm arteries, bilateral arm AV fistula, bilateral subclavian artery[clevelandclinicmeded.com]

  • Adrenal Insufficiency

    aortic valve, permitting blood to flow back into the left ventricle of the heart. cardiac insufficiency inability of the heart to perform its function properly; heart failure[medical-dictionary.thefreedictionary.com] A 65-year-old male with liver cirrhosis of alcoholic etiology was admitted to hospital with bilateral leg edema, ascites, and marked weakness.[ncbi.nlm.nih.gov] […] through the orifice (valvular regurgitation); named, according to the valve affected, aortic, mitral, pulmonary or tricuspid insufficiency. velopharyngeal insufficiency failure[medical-dictionary.thefreedictionary.com]

  • Meningovascular Syphilis

    Aortic valve insufficiency may result. Neurosyphilis has several forms. If the spirochete invades the CNS, syphilitic meningitis results.[emedicine.medscape.com] The present symptoms started with slight weakness of bilateral legs after he was awake. He felt dizzy and had difficulty in standing up from bed and walking.[file.scirp.org] The aortitis leads to slowly progressive dilation of the aortic root and arch, which causes aortic valve insufficiency and aneurysms of the proximal aorta.[humpath.com]

  • Upper Limb Hypertrophy

    Current data suggest that this risk is less likely a direct consequence of the coarctation and more likely related to a bicuspid aortic valve and associated aortopathy.[msdmanuals.com] Patient’s face showed gross lipodystropy, wasting of sternmastoid muscles and upper arms muscles, bilaterally ( figure 4A-4D ).[omicsonline.org] Symptoms and Signs If coarctation is significant, circulatory shock with renal insufficiency (oliguria or anuria) and metabolic acidosis may develop in the first 7 to 10 days[msdmanuals.com]

  • Weissenbacher-Zweymuller Syndrome

    valve disease NOTCH2 Alagille syndrome, Hajdu-Cheney syndrome NPR2 Acromesomelic dysplasia type Maroteaux, Epiphyseal chondrodysplasia, Miura, Short stature with nonspecific[genda.com.ar] Figure 7 Patient 2: Lateral radiograph of the knee with the leg internally rotated (10–20 ) showed bilateral irregularity of the apophysis with separation from the tibial[ped-rheum.biomedcentral.com] , Multiple synostosis syndrome, Stapes ankylosis with broad thumb and toes (Teunissen-Cremers syndrome), Symphalangism, proximal, Tarsal-carpal coalition syndrome NOTCH1 Aortic[genda.com.ar]

  • Hypermobility Syndrome

    Symptoms are usually bilateral, in the low back, buttocks, or thighs, although some individuals may experience only leg pain and, in a few cases, the leg pain may be unilateral[ssa.gov] Cardiovascular: Aortic root dilatation, aortic aneurysm, aortic dissection, aortic insufficiency, mitral valve prolapse, endocarditis, left ventricular dysfunction Ophthalmologic[rheumatologyadvisor.com] Pseudoclaudication, which may result from lumbar spinal stenosis, is manifested as pain and weakness, and may impair ambulation.[ssa.gov]

  • Cyclophosphamide

    Over the following 2 weeks, he developed further paraesthesia in the fingers and severe shooting pain in the right leg.[rheumatology.oxfordjournals.org] Valve Disorder / Aortic Valve Insufficiency / Aortic Valve Stenosis / Regurgitation, Aortic Valve 1 4RecruitingTreatment Aortic Valve Stenosis / Strokes 1 4RecruitingTreatment[drugbank.ca] He also developed bilateral ankle synovitis. The initial peripheral eosinophilia had resolved, but the CRP remained high at 100 mg/l.[rheumatology.oxfordjournals.org]

  • Disulfiram

    .— A 52-year-old man had rheumatic aortic insufficiency dating back at least to 1959. He had severe congestive failure.[jamanetwork.com] […] burning dysesthesias, numbness and pain in the soles of the feet and the legs below the knees; bilateral walking steppage, reduction in foot strength, absence of ankle jerk[ncbi.nlm.nih.gov] An aortic valve implant was performed Aug 23, 1966, with marked improvement in his cardiac reserve. Digitalis and warfarin were prescribed for him indefinitely.[jamanetwork.com]

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