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98 Possible Causes for Apathy, Deep White Matter Changes

  • Alcohol Dementia

    ARD patients often have symptoms of both forms, i.e. impaired ability to plan, apathy, and memory loss. ARD may occur with other forms of dementia (mixed dementia).[en.wikipedia.org] The CT showed prominent sulci and gyri with deep white matter changes. There were no other abnormalities.[gponline.com] Patients with alcoholic dementia often develop apathy, related to frontal lobe damage, that may mimic depression. [5] People with alcoholism are more likely to become depressed[en.wikipedia.org]

  • Binswanger Disease

    Patients with this disease usually present with apathy, agitation, and bilateral corticospinal or bulbar signs Tags: binswanger' , s-disease , subcortical-dementia , white-matter-atrophy[medicalvideos.com] OBJECTIVES: To analyse the diagnostic and prognostic value of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) magnetic resonance imaging ([ncbi.nlm.nih.gov] […] the forgetfulness of Alzheimer's disease), changes in speech, an unsteady gait, clumsiness or frequent falls, changes in personality or mood (most likely in the form of apathy[ninds.nih.gov]

  • Dementia

    Apathy, depression, irritability, agitation, and anxiety are the most frequently detected neuropsychiatric symptoms of AD.[ncbi.nlm.nih.gov] It may be particularly related to frontal deep white matter lesions. 16 Cognitive and behavioral changes in SVD are due to disruption of the frontal cortico-subcortical circuit[doi.org] A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized weakness, imbalance, apathy, memory decline[ncbi.nlm.nih.gov]

  • Multi-Infarct Dementia

    […] include: Forgetfulness (but not as severe as Alzheimer's disease) Urinary incontinence Difficulty walking Clumsiness Changes in personality or mood (most likely in the form of apathy[alzheimers.emedtv.com] Several pathogenic mechanisms appear implicated in the causation the deep white matter changes of Binswanger's disease, and hypoxia-ischemia resulting from watershed injury[web.archive.org] Psychiatric disorders are also common and include depression, apathy and personality changes.[orpha.net]

  • Normal Pressure Hydrocephalus

    Among 46 patients with suspicion of iNPH (77.6 6.7years; 34.8% women), 30 (65.2%) presented apathy (defined by a score 14 on the Starkstein apathy scale).[ncbi.nlm.nih.gov] White matter changes (WMC) INPH is known to be associated with deep white matter changes (DWMC) and smooth periventricular hyperintensity (PVH) [ 51 ] on MRI ( Figure 2B )[intechopen.com] White-matter changes: A distinction is drawn between periventricular and “deepwhite matter changes ( e49, e50 ); only the former are considered a sign of NPH.[ncbi.nlm.nih.gov]

  • Bipolar Disorder

    Some symptoms of OSA are the same as the symptoms of depression: daytime drowsiness, cognitive dysfunction, decreased drive, apathy, depressed mood, anhedonia.[ncbi.nlm.nih.gov] white matter abnormalities in individuals with BD ( Vederine et al. 2011 ; Torgerson et al. 2012).[ncbi.nlm.nih.gov] Over the past few months, her family had noted increasing apathy, lack of motivation, and a decline in her functional capacity, although she had denied feeling depressed.[web.archive.org]

  • Huntington's Disease

    Apathy severity increases in the motormanifest stages of Huntington's disease. HDGECs can adequately assess their level of apathy on a self-report questionnaire.[ncbi.nlm.nih.gov] Both deep grey matter and to a lesser degree white matter are involved in HD.[radiopaedia.org] KEYWORDS: Apathy; Health-Related Quality of Life; Huntington-s Disease[ncbi.nlm.nih.gov]

  • Toxic Encephalopathy

    Fluctuations of alertness and attention; Decreased concentration and coherent thought/skilled movements; Disorientation, memory, language, irritability and agitation, restlessness, apathy[quizlet.com] white matter changes may be seen, with the appearance of hyperintensity on T2 sequences in the region of internal capsule, corona radiata, and splenium of corpus callosum[neurologyindia.com] Wernicke's encephalopathy a neurological disorder characterized by confusion, apathy, drowsiness, ataxia of gait, nystagmus, and ophthalmoplegia; it is due to thiamine deficiency[medical-dictionary.thefreedictionary.com]

  • Tay-Sachs Disease

    Other features include apathy, uncontrollable seizures, spasticity and dementia. Death follows in the second or third year of life.[patient.info] MRI MRI is superior to CT in delineating deep white matter demyelination. Thalami may show changes consistent with calcification, best seen on T2* weighted sequences.[radiopaedia.org] Other features include apathy, uncontrollable seizures , spasticity and dementia . Death follows in the second or third year of life.[patient.info]

  • Creutzfeldt Jakob Disease

    Whether symptoms develop gradually or abruptly, mental decline progresses, often producing such symptoms as neglect of personal hygiene, apathy, and irritability.[web.archive.org] Some other features, such as the presence of abnormal hyperintensity in the periaqueductal gray matter and posterior deep white matter tracts, were also common, and although[ajnr.org] Clinical features Early in the illness, patients usually experience psychiatric or sensory symptoms, which most commonly take the form of depression, apathy or anxiety, and[web.archive.org]

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