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12 Possible Causes for Apathy, Difficulty Rising from a Squatting Position

  • Neurological Disorder

    FvFTD, exemplified here, often presents first to a psychiatrist, typically with a blunting of emotions, apathy, and egocentricity.[doi.org] rising from squatting position (use hands to ‘climb’ up legs – Gowers’ sign)  Pseudohypertrophy of calf muscles (muscle replaced by fatty tissue)  Progressive disability[slideshare.net] […] sclerosis), or Lou Gehrig’s disease Parkinson’s disease all forms of dementia Some of the more common symptoms of neurodegenerative diseases include: memory loss forgetfulness apathy[healthline.com]

  • Pellagra

    At the same time, there was noticeable improvement in the patient's depression and apathy.[ncbi.nlm.nih.gov] On examination, the main features are wasting, anaesthetic patches (especially over the tibia), tenderness of the calves to pressure and difficulty in rising from the squatting[fao.org] These are commonly seen as irritability, poor concentration, anxiety, fatigue, restlessness, apathy and depression.[ncbi.nlm.nih.gov]

  • Beriberi

    […] postoperative state, total parenteral nutrition and renal dialysis. [ 11 ] A loop diuretic can also increase the risk. [ 12 ] Presentation History Early features Fatigue and apathy[patient.info] The neuropathy affects the legs most markedly, and these patients have difficulty rising from a squatting position. [4] In our case, the patient had both features of wet and[jdrntruhs.org] It is accompanied by a degree of apathy – lack of interest in life or other activities that were previously enjoyable.[healthhype.com]

  • Wernicke Encephalopathy

    Manifestations of thiamine deficiency in infants are constipation, agitation, apathy, vomiting, lack of appetite, and later, diarrhea, grunting, nystagmus, convulsions, unconsciousness[emedicine.medscape.com] Calf muscle tenderness, difficulty rising from a squatting position, and decreased vibratory sensation in the toes are early signs. Muscle wasting occurs.[merckmanuals.com] May also include confabulation, apathy, lack of insight.[blog.ercast.org]

  • Infantile Beriberi

    Wernicke encephalopathy consists of psychomotor slowing or apathy, nystagmus, ataxia, ophthalmoplegia, impaired consciousness, and, if untreated, coma and death.[merckmanuals.com] . • lipid synthesis • gluconeogenesis This leads to Inadequate growth, Loss of weight , strength and apathy (due to decreased ATP synthesis). 11.[slideshare.net] The neuropathy affects the legs most markedly, and these patients have difficulty rising from a squatting position. [4] In our case, the patient had both features of wet and[jdrntruhs.org]

  • Thiamine Deficiency

    […] amnesia -inability to form new memories: anterograde amnesia -confabulation: the patient makes up stories which are taken as true due to gaps in memory -lack of insight -apathy[flipper.diff.org] The neuropathy affects the legs most markedly, and these patients have difficulty rising from a squatting position. [4] In our case, the patient had both features of wet and[jdrntruhs.org] In the remaining patients, apathy, apnea and/or seizures were the presenting symptoms. In two patients, neurologic examination revealed vertical nystagmus.[ajnr.org]

  • Cardiac Beriberi

    […] degeneration, peripheral nerves—myelinolysis and axonal degeneration, subcutaneous tissues–edema and vascular congestion and serosal linings–effusions Clinical Fatigue, apathy[medical-dictionary.thefreedictionary.com] The neuropathy affects the legs most markedly, and these patients have difficulty rising from a squatting position. [4] In our case, the patient had both features of wet and[jdrntruhs.org] Calf muscle tenderness, difficulty rising from a squatting position, and decreased vibratory sensation in the toes are early signs. Muscle wasting occurs.[namrata.co]

  • Hereditary Proximal Myopathy with Early Respiratory Failure

    Dementia (30% to 37%) Onset Mean 52 to 54 years; Range 39 to 62 years Usually after Paget's or Myopathy Frontotemporal Language: Anomia; Aphasia; Mutism Personality change: Apathy[neuromuscular.wustl.edu] They presented between the ages of 13 to 29 with proximal weakness in the lower extremities manifesting with difficulty on stairs or rising up from a squatting position (Table[bmcneurol.biomedcentral.com]

  • Distal Myopathy Type 3

    Dementia (30% to 37%) Onset Mean 52 to 54 years; Range 39 to 62 years Usually after Paget's or Myopathy Frontotemporal Language: Anomia; Aphasia; Mutism Personality change: Apathy[neuromuscular.wustl.edu] Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] […] up from a squatted position, climbing stairs.[sites.google.com]

  • Distal Myopathy

    Dementia (30% to 37%) Onset Mean 52 to 54 years; Range 39 to 62 years Usually after Paget's or Myopathy Frontotemporal Language: Anomia; Aphasia; Mutism Personality change: Apathy[neuromuscular.wustl.edu] Pelvic girdle Difficulty climbing stairs, waddling gait, difficulty rising to standing position from a squatting position (patient may demonstrate Gower sign), difficulty[sites.google.com] […] up from a squatted position, climbing stairs.[sites.google.com]

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